Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Meizhu Zhang"'
Autor:
Xiaopeng Peng, Zhihao Hu, Limei Zeng, Meizhu Zhang, Congcong Xu, Benyan Lu, Chengpeng Tao, Weiming Chen, Wen Hou, Kui Cheng, Huichang Bi, Wanyi Pan, Jianjun Chen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 2, Pp 533-578 (2024)
Epigenetic pathways play a critical role in the initiation, progression, and metastasis of cancer. Over the past few decades, significant progress has been made in the development of targeted epigenetic modulators (e.g., inhibitors). However, epigene
Externí odkaz:
https://doaj.org/article/e9f9f251319d4fdf92ac3cb5930c5c4c
Autor:
Xiaopeng Peng, Ziwen Yu, Goverdhan Surineni, Bulian Deng, Meizhu Zhang, Chuan Li, Zhiqiang Sun, Wanyi Pan, Yao Liu, Shenglan Liu, Bin Yu, Jianjun Chen
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
In this study, a novel series of histone deacetylases 6 (HDAC6) inhibitors containing polycyclic aromatic rings were discovered and evaluated for their pharmacological activities. The most potent compound 10c exhibited high HDAC6 inhibitory activity
Externí odkaz:
https://doaj.org/article/88ad33862024465eabf4c987c34fa3eb
Publikováno v:
Computers and Geotechnics. 158:105339
Publikováno v:
Arabian Journal for Science and Engineering.
Publikováno v:
Bulletin of Engineering Geology and the Environment. 80:1617-1634
Hard rock often performs as brittle failures, such as cracking, spalling, and rockburst, induced by excavation in deep underground engineering. To understand the effect of the minimum principal stress and unloading rate on the spalling and rockburst
Publikováno v:
Arabian Journal of Geosciences. 14
In carbonate fracture-cavity reservoirs, the resource of gas/oil mainly distributes in natural fractures and caves; therefore, it is critical to understand the property of the pre-existing caves. However, currently it is still lack of direct method t
Publikováno v:
CrystEngComm. 20:3550-3558
Surface-enhanced Raman scattering (SERS) is one of the most promising methods in detecting trace amounts of molecules owing to its high sensitivity, fast response, and high molecular specificity. One of the key issues for SERS applications is to fabr
Publikováno v:
Applied Geochemistry. 24:172-183
Relatively abundant C30 17α(H)-diahopane has been detected in oils and rock extracts in the Fushan Depression, a Tertiary lacustrine basin of the Northern South China Sea. C30 17α(H)-diahopane/(C30 17α(H)-diahopane + C30 17α(H)-hopane) ratios (DI
Publikováno v:
Science in China Series D: Earth Sciences. 51:138-145
The condensates are generally characterized by high maturity, low concentration of steranes and terpanes biomarkers and low content of non-hydrocarbon fraction. In this case commonly used steranes, terpanes and carbazoles parameters cannot be effecti
Publikováno v:
Acta Geologica Sinica (English Edition); Oct2010, Vol. 84 Issue 5, p1294-1305, 12p, 3 Diagrams, 3 Charts, 6 Graphs, 2 Maps