Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Meiyu Qv"'
Autor:
Ling-Hui Zeng, Chao Tang, Minli Yao, Qiangqiang He, Meiyu Qv, Qianlei Ren, Yana Xu, Tingyu Shen, Weizhong Gu, Chengyun Xu, Chaochun Zou, Xing Ji, Ximei Wu, Jirong Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Aberrant activation of sonic hedgehog (SHH) signaling and its effector transcriptional factor GLI1 are essential for oncogenesis of SHH-dependent medulloblastoma (MBSHH) and basal cell carcinoma (BCC). Here, we show that SHH inactivates p38
Externí odkaz:
https://doaj.org/article/28574c1ec61742cea958ccacabc3e043
Autor:
Wei Shi, Chengyun Xu, Ying Gong, Jirong Wang, Qianlei Ren, Ziyi Yan, Liu Mei, Chao Tang, Xing Ji, Xinhua Hu, Meiyu Qv, Musaddique Hussain, Ling-Hui Zeng, Ximei Wu
Publikováno v:
Cell Regeneration, Vol 13, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/e6933c1d92d444458daca4911b160ca4
Autor:
Dan Tan, Meiping Lu, Yuqing Cai, Weibo Qi, Fugen Wu, Hangyang Bao, Meiyu Qv, Qiangqiang He, Yana Xu, Xiangzhi Wang, Tingyu Shen, Jiahao Luo, Yangxun He, Junsong Wu, Lanfang Tang, Muhammad Qasim Barkat, Chengyun Xu, Ximei Wu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Allergic asthma is characterized by goblet cell metaplasia and subsequent mucus hypersecretion that contribute to the morbidity and mortality of this disease. Here, we explore the potential role and underlying mechanism of protein SUMOylatio
Externí odkaz:
https://doaj.org/article/ef3e5e6745f94651a9907aa6ed60281f
Autor:
Yingying Shu, Chaochun Zou, Yuqing Cai, Qiangqiang He, Xiaowei Wu, Haibin Zhu, Meiyu Qv, Yunqi Chao, Chengyun Xu, Lanfang Tang, Ximei Wu
Publikováno v:
Redox Biology, Vol 56, Iss , Pp 102420- (2022)
Vitamin C (VC, l-ascorbic acid) is an essential nutrient that plays a key role in metabolism and functions as a potent antioxidant in regulating the S-nitrosylation and denitrosylation of target proteins. The precise function of VC deprivation in glu
Externí odkaz:
https://doaj.org/article/f05bb5293ebc4f0291eeaafc12a0200b
Autor:
Wei Shi, Chengyun Xu, Ying Gong, Jirong Wang, Qianlei Ren, Ziyi Yan, Liu Mei, Chao Tang, Xing Ji, Xinhua Hu, Meiyu Qv, Musaddique Hussain, Ling-Hui Zeng, Ximei Wu
Publikováno v:
Cell Regeneration, Vol 10, Iss 1, Pp 1-19 (2021)
Abstract The Wnt/β-catenin signaling pathway appears to be particularly important for bone homeostasis, whereas nuclear accumulation of β-catenin requires the activation of Rac1, a member of the Rho small GTPase family. The aim of the present study
Externí odkaz:
https://doaj.org/article/e626f1c66e1342058ad04833055f8769
Autor:
Liu, Mei, Meiyu, Qv, Hangyang, Bao, Qiangqiang, He, Yana, Xu, Qin, Zhang, Wei, Shi, Qianlei, Ren, Ziyi, Yan, Chengyun, Xu, Chao, Tang, Musaddique, Hussain, Ling-Hui, Zeng, Ximei, Wu
Publikováno v:
Oncogene. 40(35)
Large tumour suppressor (LATS) 1/2, the core kinases of Hippo signalling, are critical for maintaining tissue homeostasis. Here, we investigate the role of SUMOylation in the regulation of LATS activation. High cell density induces the expression of
Autor:
Ling-Hui Zeng, Dan Tan, Junsong Wu, Meiyu Qv, Xiaotian Du, Liu Mei, Qin Zhang, Qiangqiang He, Wei Shi, Ximei Wu
Publikováno v:
Life sciences. 264
Aim Large tumor suppressor 1 (LATS1) is a Ser/Thr kinase to mediate Hippo signaling pathway and plays a pivotal role in tumor suppression. By searching the COSMIC database, we found a somatic missense mutation (NM_004690.4:c.2552C>T) of human LATS1 (