Zobrazeno 1 - 10
of 324
pro vyhledávání: '"Meiwan, Chen"'
Publikováno v:
Bioactive Materials, Vol 36, Iss , Pp 83-95 (2024)
Abnormal proliferation of aggressive fibroblast-like synoviocytes (FLS) and perpetuate synovial inflammation can inevitably accelerate the progression of rheumatoid arthritis (RA). Herein, a strategy of simultaneously promoting FLS apoptosis and inhi
Externí odkaz:
https://doaj.org/article/4a66ba84ac64424cb7dfcb80de756935
Autor:
Yupei Zhang, Songhui Zhai, Hai Huang, Shugang Qin, Min Sun, Yuting Chen, Xing Lan, Guohong Li, Zhiying Huang, Denggang Wang, Yaoyao Luo, Wen Xiao, Hao Li, Xi He, Meiwan Chen, Xingchen Peng, Xiangrong Song
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract The signal sequence played a crucial role in the efficacy of mRNA vaccines against virus pandemic by influencing antigen translation. However, limited research had been conducted to compare and analyze the specific mechanisms involved. In th
Externí odkaz:
https://doaj.org/article/8320420af43a40c6a212131d7d5098fe
Autor:
Zhiting Liu, Jiaying Huang, Danqiao Fang, Bohua Feng, Jianxu Luo, Peixuan Lei, Xiaoling Chen, Qingchun Xie, Meiwan Chen, Peihong Chen
Publikováno v:
Materials Today Bio, Vol 27, Iss , Pp 101153- (2024)
The advantage of low-temperature forming through direct ink writing (DIW) 3D printing is becoming a strategy for the construction of innovative drug delivery systems (DDSs). Optimization of the complex formulation, including factors such as the print
Externí odkaz:
https://doaj.org/article/dbcf9450881f404a94372ac08e8d1638
Autor:
Ke-Gang Linghu, Tian Zhang, Guang-Tao Zhang, Peng Lv, Wen-Jun Zhang, Guan-Ding Zhao, Shi-Hang Xiong, Qiu-Shuo Ma, Ming-Ming Zhao, Meiwan Chen, Yuan-Jia Hu, Chang-Sheng Zhang, Hua Yu
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 3, Pp 401-415 (2024)
Activation of nuclear factor erythroid 2-related factor 2 (Nrf2) by Kelch-like ECH-associated protein 1 (Keap1) alkylation plays a central role in anti-inflammatory therapy. However, activators of Nrf2 through alkylation of Keap1-Kelch domain have no
Externí odkaz:
https://doaj.org/article/f75993c98ed24cf58861ad94efe72201
Autor:
Qiwei Jiang, Yong Li, Songwang Cai, Xingyuan Shi, Yang Yang, Zihao Xing, Zhenjie He, Shengte Wang, Yubin Su, Meiwan Chen, Zhesheng Chen, Zhi Shi
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 2, Pp 698-711 (2024)
Glutamate-ammonia ligase (GLUL, also known as glutamine synthetase) is a crucial enzyme that catalyzes ammonium and glutamate into glutamine in the ATP-dependent condensation. Although GLUL plays a critical role in multiple cancers, the expression an
Externí odkaz:
https://doaj.org/article/ad5ca24d1e9e498fa1b7c96486c8f313
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 12, Pp 5016-5029 (2023)
Normalizing inflamed soils including reactive oxygen species (ROS), nitric oxide (NO), cell-free DNA, and regulating inflammation-related seeds such as macrophages, neutrophils, fibroblasts, represent a promising strategy to maintain synovial tissu
Externí odkaz:
https://doaj.org/article/23649abf9e4d4d25a4851d39502cdacd
Publikováno v:
Chinese Medicine, Vol 18, Iss 1, Pp 1-14 (2023)
Abstract Background The integration of photodynamic therapy with a chemical drug-delivery system has displayed great potential in enhancing anticancer therapy. However, the solubility and non-specific biodistribution of both chemotherapeutic agents a
Externí odkaz:
https://doaj.org/article/f50ea49e7f5845b196f44c56f6e6d6ed
Autor:
Ke-Gang Linghu, Qiushuo Ma, Shi-Hang Xiong, Mingming Zhao, Qiling Chen, Wen Xu, Meiwan Chen, Jian-Ye Zhang, Yuanjia Hu, Wei Xu, Hua Yu
Publikováno v:
Chinese Medicine, Vol 17, Iss 1, Pp 1-12 (2022)
Abstract Background Ulcerative colitis (UC) is a common inflammatory intestinal disease. Astragali Radix (AR) is one of the traditional Chinese medicines used in clinic for UC treatment. In our previous study, the whole ingredient extract (WIE) from
Externí odkaz:
https://doaj.org/article/ebfb32eafe194791b0c07b8d7d53cdbd
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 9, Pp 3567-3593 (2022)
As an emerging cancer therapeutic target, non-apoptotic cell death such as ferroptosis, necroptosis and pyroptosis, etc., has revealed significant potential in cancer treatment for bypassing apoptosis to enhance the undermined therapeutic efficacy tr
Externí odkaz:
https://doaj.org/article/a57c1a2b0b16463c8d39fd111639efae
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 17, Iss 4, Pp 475-490 (2022)
Dihydroartemisinin (DHA), a first-line antimalarial drug, has demonstrated great anticancer effects in many types of tumors, including liver cancer, glioblastoma, and pancreatic cancer. Due to its abilities to induce programmed cell death (PCD; apopt
Externí odkaz:
https://doaj.org/article/0d57855d8d5841e19d72b72c885a3ecb