Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Meiqian Qian"'
Autor:
Haiyan Zheng, Jennifer A. Wiseman, Winnie Xin, Rosemary Barone, Katherine B. Sims, Dirk F. Moore, Istvan Sohar, David E. Sleat, Caifeng Zhao, Peter Lobel, Meiqian Qian, Abla Tannous
Publikováno v:
Journal of Proteome Research. 16:3787-3804
Clinical trials have been conducted for the neuronal ceroid lipofuscinoses (NCLs), a group of neurodegenerative lysosomal diseases that primarily affect children. Whereas clinical rating systems will evaluate long-term efficacy, biomarkers to measure
Autor:
Meiqian Qian, Marielle Boonen, Nan Wang, Haiyan Zheng, Caifeng Zhao, Jacqueline Thirion, David E. Sleat, Peter Lobel, Michel Jadot, Jinchuan Xing, Abla Tannous, Dirk F. Moore, John K. Everett
Publikováno v:
Jadot, M, Boonen, M, Thirion, J, Wang, N, Xing, J, Zhao, C, Tannous, A, Qian, M, Zheng, H, Everett, J K, Moore, D F, Sleat, D E & Lobel, P 2017, ' Accounting for protein subcellular localization : A compartmental map of the rat liver proteome ', Molecular & cellular proteomics : MCP, vol. 16, no. 2, pp. 194-212 . https://doi.org/10.1074/mcp.M116.064527
Accurate knowledge of the intracellular location of proteins is important for numerous areas of biomedical research including assessing fidelity of putative proteinprotein interactions, modeling cellular processes at a system-wide level and investiga
Autor:
Patrick Chu, Robert J. Hariri, Dariani Maghsoud, Sushmita Mimi Roy, Meiqian Qian, Haiyan Zheng, Alex Tess, Neerav D. Padliya
Publikováno v:
Food & Function. 6:2303-2314
Chicken egg yolk is a rich source of nutrients providing high quality proteins, vitamins, minerals, carotenoids and antioxidants. Chicken egg yolk, recovered from whole egg within 24 hours post-lay has been utilized as a starting material in the prep
Autor:
Yi Qian, Peter Lobel, Mariko Kudo, Stuart Kornfeld, Meiqian Qian, Wang Sik Lee, William M. Canfield, Intaek Lee
Publikováno v:
Journal of Biological Chemistry. 285:3360-3370
UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase is an alpha(2)beta(2)gamma(2) hexamer that mediates the first step in the synthesis of the mannose 6-phosphate recognition marker on lysosomal acid hydrolases. Using a multifaceted
Publikováno v:
Molecular & Cellular Proteomics. 7:58-70
Most mammalian cells contain two types of mannose 6-phosphate (Man-6-P) receptors (MPRs): the 300 kDa cation-independent (CI) MPR and 46 kDa cation-dependent (CD) MPR. The two MPRs have overlapping function in intracellular targeting of newly synthes
Publikováno v:
Microbial Cell Factories
Background The methylotrophic yeast, Pichia pastoris, is widely used as a useful experimental tool in protein engineering and production. It is common for proteins expressed in P. pastoris to exhibit N-glycosylation. In recent years, glycosylation st
Autor:
Swapan Roy, Matthew Kuruc, Haiyan Zheng, Meiqian Qian, Caifeng Zhao, Amenah Soherwardy, Absari Arpa
Publikováno v:
Journal of Proteomics & Bioinformatics.
For cancer research, serum and plasma are especially attractive sample types as collection of blood is common, simple and only minimally invasive. Yet serum samples can offer unique challenges in LC-MS proteomic analyses. The two biggest challenges b
Publikováno v:
Molecular & Cellular Proteomics. 5:686-701
Most newly synthesized soluble lysosomal proteins contain mannose 6-phosphate (Man-6-P), a specific carbohydrate modification that is recognized by Man-6-P receptors (MPRs) that direct targeting to the lysosome. A number of proteomic studies have foc
Autor:
Minghua Yang, Xiangyin Kong, Landian Hu, Guangyong Zheng, Meiqian Qian, Shangxi Xiao, Jing Liu, Liqin Zhu, Lei Bu, Guoping Zhao
Publikováno v:
Genomics. 74:180-185
Gingival fibromatosis ( GINGF ) is an oral disorder characterized by enlargement of the gingiva. It occurs either as the sole phenotype or combined with other symptoms. Thus far, one GINGF locus has been mapped on chromosome 2, at 2p21, and a second
Autor:
Landian Hu, Zhu Chen, Lei Bu, Xueming Chou, Jun J. Yang, Gang Fu, Xiangyin Kong, Guoping Zhao, Wenjuan Yuan, Ying Wang, Chuan Yu, Zhengmin Wang, Wei Huang, Yaozhou Shi, Bin Han, Meiqian Qian, Shangxi Xiao, Jing Liu
Publikováno v:
Nature Genetics. 27:201-204
Dentinogenesis imperfecta 1 (DGI1, MIM 125490) is an autosomal dominant dental disease characterized by abnormal dentin production and mineralization. The DGI1 locus was recently refined to a 2-Mb interval on 4q21 (ref. 1). Here we study three Chines