Exploiting Translation Machinery for Cancer Therapy: Translation Factors as Promising Targets.

Autor: Sehrawat, Urmila¹ (AUTHOR) sehrawu@mskcc.org

Publikováno v: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 19, p10835. 24p.

Synthesis of 4- and 5-arylthiazolinethiones as inhibitors of indoleamine 2,3-dioxygenase.

Autor: Balti M; NAMEDIC-NARILIS, University of Namur, 61 Rue de Bruxelles, 5000 Namur, Belgium; Laboratory of Organic Synthesis and Heterocyclic Chemistry, Department of Chemistry, College of Sciences at Tunis, El Manar University, Campus, 1060 Tunis, Tunisia., Plas A; NAMEDIC-NARILIS, University of Namur, 61 Rue de Bruxelles, 5000 Namur, Belgium., Meinguet C; NAMEDIC-NARILIS, University of Namur, 61 Rue de Bruxelles, 5000 Namur, Belgium., Haufroid M; NAMEDIC-NARILIS, University of Namur, 61 Rue de Bruxelles, 5000 Namur, Belgium., Thémans Q; NAMEDIC-NARILIS, University of Namur, 61 Rue de Bruxelles, 5000 Namur, Belgium., Efrit ML; Laboratory of Organic Synthesis and Heterocyclic Chemistry, Department of Chemistry, College of Sciences at Tunis, El Manar University, Campus, 1060 Tunis, Tunisia., Wouters J; NAMEDIC-NARILIS, University of Namur, 61 Rue de Bruxelles, 5000 Namur, Belgium., Lanners S; NAMEDIC-NARILIS, University of Namur, 61 Rue de Bruxelles, 5000 Namur, Belgium. Electronic address: steve.lanners@unamur.be.

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2017 Aug 01; Vol. 27 (15), pp. 3607-3610. Date of Electronic Publication: 2016 Jun 18.

Data in support of a harmine-derived beta-carboline in vitro effects in cancer cells through protein synthesis.

Autor: Carvalho A; Laboratoire de Cancérologie et Toxicologie Expérimentale, Faculté de Pharmacie, Université Libre de Bruxelles, Brussels, Belgium., Chu J; Department of Biochemistry, McGill University, Montreal, Québec, Canada., Meinguet C; Namur Medicine and Drug Innovation Center (NAMEDIC-NARILIS), Université de Namur, Namur, Belgium., Kiss R; Laboratoire de Cancérologie et Toxicologie Expérimentale, Faculté de Pharmacie, Université Libre de Bruxelles, Brussels, Belgium., Vandenbussche G; Laboratory for the Structure and Function of Biological Membranes, Faculté des Sciences, Université Libre de Bruxelles, Brussels, Belgium., Masereel B; Namur Medicine and Drug Innovation Center (NAMEDIC-NARILIS), Université de Namur, Namur, Belgium., Wouters J; Namur Medicine and Drug Innovation Center (NAMEDIC-NARILIS), Université de Namur, Namur, Belgium., Kornienko A; Department of Chemistry and Biochemistry, Texas State University, 601 University Drive, San Marcos, TX 78666, USA., Pelletier J; Department of Biochemistry, McGill University, Montreal, Québec, Canada., Mathieu V; Laboratoire de Cancérologie et Toxicologie Expérimentale, Faculté de Pharmacie, Université Libre de Bruxelles, Brussels, Belgium.

Publikováno v: Data in brief [Data Brief] 2017 May 05; Vol. 12, pp. 546-551. Date of Electronic Publication: 2017 May 05 (Print Publication: 2017).

3D-QSAR, design, synthesis and characterization of trisubstituted harmine derivatives with in vitro antiproliferative properties.

Autor: Meinguet C; Namur Medicine & Drug Innovation Center (NAMEDIC-NARILIS), University of Namur (Unamur), 61, rue de Bruxelles, 5000 Namur, Belgium. Electronic address: celine.meinguet@unamur.be., Bruyère C; Laboratoire de Cancérologie et de Toxicologie Expérimentale, Faculté de Pharmacie, Université Libre de Bruxelles (ULB), Boulevard du Triomphe, 1050 Brussels, Belgium., Frédérick R; Medicinal Chemistry Research Group (CMFA), University of Louvain (UCL), 73, Avenue Mounier, 1200 Bruxelles, Belgium., Mathieu V; Laboratoire de Cancérologie et de Toxicologie Expérimentale, Faculté de Pharmacie, Université Libre de Bruxelles (ULB), Boulevard du Triomphe, 1050 Brussels, Belgium., Vancraeynest C; Namur Medicine & Drug Innovation Center (NAMEDIC-NARILIS), University of Namur (Unamur), 61, rue de Bruxelles, 5000 Namur, Belgium., Pochet L; Namur Medicine & Drug Innovation Center (NAMEDIC-NARILIS), University of Namur (Unamur), 61, rue de Bruxelles, 5000 Namur, Belgium., Laloy J; Namur Medicine & Drug Innovation Center (NAMEDIC-NARILIS), University of Namur (Unamur), 61, rue de Bruxelles, 5000 Namur, Belgium., Mortier J; Institute of Pharmacy, Freie Universität Berlin, 2+4 Königin Luise Straβe, 14195 Berlin, Germany., Wolber G; Institute of Pharmacy, Freie Universität Berlin, 2+4 Königin Luise Straβe, 14195 Berlin, Germany., Kiss R; Laboratoire de Cancérologie et de Toxicologie Expérimentale, Faculté de Pharmacie, Université Libre de Bruxelles (ULB), Boulevard du Triomphe, 1050 Brussels, Belgium., Masereel B; Namur Medicine & Drug Innovation Center (NAMEDIC-NARILIS), University of Namur (Unamur), 61, rue de Bruxelles, 5000 Namur, Belgium., Wouters J; Namur Medicine & Drug Innovation Center (NAMEDIC-NARILIS), University of Namur (Unamur), 61, rue de Bruxelles, 5000 Namur, Belgium.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2015 Apr 13; Vol. 94, pp. 45-55. Date of Electronic Publication: 2015 Feb 24.

Indoleamine 2,3-dioxygenase inhibitory activity of derivatives of marine alkaloid tsitsikammamine A.

Autor: Dolušić E; Namur Medicine & Drug Innovation Center, Namur Research Institute for Life Sciences, University of Namur, 61 Rue de Bruxelles, B-5000 Namur, Belgium. eduard.dolusic@fundp.ac.be, Larrieu P, Meinguet C, Colette D, Rives A, Blanc S, Ferain T, Pilotte L, Stroobant V, Wouters J, Van den Eynde B, Masereel B, Delfourne E, Frédérick R

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2013 Jan 01; Vol. 23 (1), pp. 47-54. Date of Electronic Publication: 2012 Nov 22.