Zobrazeno 1 - 10
of 482
pro vyhledávání: '"Meindert Danhof"'
Autor:
Meindert Danhof, Piet H. van derGraaf, Teun M. Post, Sandra A. G. Visser, Klaas P. Zuideveld, Stephan Schmidt
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 10, Pp 1611-1614 (2024)
Externí odkaz:
https://doaj.org/article/7229f7d712ec49b281cac6965351a005
Autor:
Heleen J. Blussé van Oud-Alblas, Margreke J. E. Brill, Mariska Y. M. Peeters, Dick Tibboel, Meindert Danhof, Catherijne A. J. Knibbe
Publikováno v:
BMC Anesthesiology, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background In adolescents limited data are available on the pharmacokinetics (PK) and pharmacodynamics (PD) of propofol. In this study we derived a PK-PD model for propofol in adolescents undergoing idiopathic scoliosis surgery with an intra
Externí odkaz:
https://doaj.org/article/2e21509f15884249a1bf9c8f16b20547
Autor:
Amit Taneja, An Vermeulen, Dymphy R.H. Huntjens, Meindert Danhof, Elizabeth C.M. De Lange, Johannes H. Proost
Publikováno v:
Data in Brief, Vol 8, Iss , Pp 1433-1437 (2016)
We provide the reader with relevant data related to our recently published paper, comparing two mathematical models to describe prolactin turnover in rats following one or two doses of the dopamine D2 receptor antagonists risperidone, paliperidone an
Externí odkaz:
https://doaj.org/article/64448badcc4a41b9b559f9d8583b6b3d
Autor:
Chi Hse Tang, Mathieu Peyrou, Jonathan P. Mochel, Meindert Danhof, Dean F. Rigel, Jérôme M. Giraudel
Publikováno v:
European Journal of Pharmaceutical Sciences. 128:103-111
Simultaneous blockade of angiotensin receptors and enhancement of natriuretic peptides (NP) by the first-in-class angiotensin receptor neprilysin (NEP) inhibitor sacubitril/valsartan constitutes an effective approach to treating heart failure. This s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc9b80df68ea7b340913c67e41c7eaf
https://doi.org/10.1016/j.ejps.2018.11.037
https://doi.org/10.1016/j.ejps.2018.11.037
Autor:
Meindert Danhof, Sheraz Gul, Dymphy Huntjens, Piet H. van der Graaf, Solene Rolland, Maria Kuzikov, Wilhelmus E. A. de Witte, Victoria Georgi, Amaury Ernesto Fernandez-Montalvan, Philip Gribbon, Joost W Versfelt, Gesa Witt, Elizabeth C. M. de Lange
Publikováno v:
British Journal of Pharmacology
and the cAMP turnover.\n .\n receptor antagonists, it has been hypothesized that fast receptor binding kinetics cause fewer side effects, because part of the dynamics of the dopaminergic system is preserved by displacement of these antagonists.\n rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e527343b7a7356185c4a4adf14aa78a0
https://doi.org/10.1111/bph.14456
https://doi.org/10.1111/bph.14456
Autor:
Meindert Danhof, Piet H. van der Graaf, Elizabeth C. M. de Lange, Lambertus A. Peletier, Vivi Rottschäfer, Wilhelmus E. A. de Witte
Publikováno v:
Journal of Pharmacokinetics and Pharmacodynamics
Journal of Pharmacokinetics and Pharmacodynamics, 45(4), 621-635
Journal of Pharmacokinetics and Pharmacodynamics, 45(4), 621-635
Drug–target binding kinetics (as determined by association and dissociation rate constants, kon and koff) can be an important determinant of the kinetics of drug action. However, the effect compartment model is used most frequently instead of a tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531a32e4c4efba32fd8afe34aae0001a
https://doi.org/10.1007/s10928-018-9593-x
https://doi.org/10.1007/s10928-018-9593-x
Autor:
Julie A. Stone, Huub Jan Kleijn, Eline M. T. van Maanen, Mary J. Savage, Maria S. Michener, Matthew E. Kennedy, Tamara J. van Steeg, Maurice J. Ahsman, Meindert Danhof
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 365:507-518
The abnormal accumulation of amyloid-β (Aβ) in the brain parenchyma has been posited as a central event in the pathophysiology of Alzheimer's disease. Recently, we have proposed a systems pharmacology model of the amyloid precursor protein (APP) pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73ed61ef3a7f9abe38bdca2d3a0add1f
https://doi.org/10.1124/jpet.117.244699
https://doi.org/10.1124/jpet.117.244699
Autor:
Huixin Yu, Pyry A. J. Välitalo, Dick Tibboel, Piet H. van der Graaf, Trevor N. Johnson, Amin Rostami-Hodjegan, Elisa A. M. Calvier, Catherijne A. J. Knibbe, Elke H. J. Krekels, Meindert Danhof
Publikováno v:
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
For scaling drug plasma clearance (CLp) from adults to children, extrapolations of population pharmacokinetic (PopPK) covariate models between drugs sharing an elimination pathway have enabled accelerated development of pediatric models and dosing re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da2030bb7b75dd112ba65f1045fe8012
https://doi.org/10.1002/psp4.12273
https://doi.org/10.1002/psp4.12273
Autor:
Nico C. B. de Jager, Meindert Danhof, Sven C. van Dijkman, Oscar Della Pasqua, Willem M. Rauwé
Publikováno v:
Clinical Pharmacokinetics. 57:1039-1053
In this study, we evaluate the performance of allometric concepts to predict the implications of age and size on the pharmacokinetics of lamotrigine, and assess the dose rationale across different age groups from 0.2 to 91 years.An allometrically sca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2f012b0ecee20bec6b756c573e85671
https://doi.org/10.1007/s40262-017-0614-5
https://doi.org/10.1007/s40262-017-0614-5
Publikováno v:
British Journal of Clinical Pharmacology. 84:97-111
Aims Population pharmacokinetic modelling has been widely used across many therapeutic areas to identify sources of variability, which are incorporated into models as covariate factors. Despite numerous publications on pharmacokinetic drug–drug int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4e217ce3568a4bd7e94922a71fe5a69
https://doi.org/10.1111/bcp.13400
https://doi.org/10.1111/bcp.13400