Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Meimi Zhao"'
Autor:
Bing Xu, Sherif Bahriz, Victoria R. Salemme, Ying Wang, Chaoqun Zhu, Meimi Zhao, Yang K. Xiang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 12 (2024)
Background Chronic sympathetic stimulation drives desensitization and downregulation of β1 adrenergic receptor (β1AR) in heart failure. We aim to explore the differential downregulation subcellular pools of β1AR signaling in the heart. Methods and
Externí odkaz:
https://doaj.org/article/4b237769ac1048998f02d9e4c2aae20f
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-11 (2022)
Highlights Design a FRET-based biosensor to monitor PKA dynamics at the RyR2 nanodomains in myocytes Stimulation of β1AR promotes PKA activity at both RyR2 and SERCA2a nanodomains whereas stimulation of β2AR does not Inhibition of PDE3 and PDE4 enh
Externí odkaz:
https://doaj.org/article/7111e54852a64d15b0c529b3d9cf71da
Publikováno v:
Cells, Vol 12, Iss 12, p 1667 (2023)
Pathological cardiac hypertrophy is one of the notable causes of heart failure. Circular RNAs (circRNAs) have been studied in association with cardiac hypertrophy; however, the mechanisms by which circRNAs regulate cardiac hypertrophy remain unclear.
Externí odkaz:
https://doaj.org/article/47f6d7bebac443ee87dcc2deba7a80b3
Autor:
Jingyuan Li, Qinghua Gao, Siqi Wang, Ze Kang, Zhuo Li, Shuai Lei, Xuefei Sun, Meimi Zhao, Xiye Chen, Guangyu Jiao, Huiyuan Hu, Liying Hao
Publikováno v:
Journal of Pharmacological Sciences, Vol 144, Iss 1, Pp 30-42 (2020)
To understand the mechanism underlying the regression of cardiac hypertrophy, we investigated the pathological changes after isoproterenol (ISO) withdrawal in ISO-induced cardiomyopathy models in rats and neonatal cardiomyocytes. Cardiac hypertrophy
Externí odkaz:
https://doaj.org/article/17f06f195f894fa68612b8332a63b4bf
Publikováno v:
Cells, Vol 11, Iss 5, p 777 (2022)
Heart failure is a major global health concern. Noncoding RNAs (ncRNAs) are involved in physiological processes and in the pathogenesis of various diseases, including heart failure. ncRNAs have emerged as critical components of transcriptional regula
Externí odkaz:
https://doaj.org/article/595aeae9c0fc4eb0855acf488086138c
Autor:
Meimi Zhao, Rui Feng, Dongxue Shao, Shuyuan Liu, Ming Lei, Hongmei Wang, Xuefei Sun, Feng Guo, Huiyuan Hu, Masaki Kameyama, Liying Hao
Publikováno v:
Journal of Pharmacological Sciences, Vol 129, Iss 3, Pp 143-149 (2015)
This study aimed to investigate the intracellular Mg2+ regulation of the L-type Ca2+ channels in guinea pig ventricular myocytes. By adopting the inside-out configuration of the patch clamp technique, single channel currents of the L-type Ca2+ channe
Externí odkaz:
https://doaj.org/article/cdbe2d1cba1a42c18af7429e014154e5
Autor:
Runzhen Zhao, Xinrong Liang, Meimi Zhao, Shan-Lu Liu, Yao Huang, Steven Idell, Xiumin Li, Hong-Long Ji
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109725 (2014)
Links between epithelial ion channels and chronic obstructive pulmonary diseases (COPD) are emerging through animal model and in vitro studies. However, clinical correlations between fluid-regulating channel proteins and lung function in COPD remain
Externí odkaz:
https://doaj.org/article/10b751d1df5e487f9b32cb00dbf5e83d
Autor:
Bing Xu, Sherif Bahriz, Salemme, Victoria R., Ying Wang, Chaoqun Zhu, Meimi Zhao, Xiang, Yang K.
Publikováno v:
Journal of the American Heart Association; 6/18/2024, Vol. 13 Issue 12, p1-17, 17p
Publikováno v:
Physiology. 38
Objective: Cardiac beta2-adrenoceptor (β2AR) has been suggested functions a protective role in defending myocyte apoptosis and cardiac damage induced by various stress. Our recent studies indicate divergent roles of cardiac β2AR in cardiomyocytes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::287ab683018a2352f24628b5cb5290a6
https://doi.org/10.1152/physiol.2023.38.s1.5734697
https://doi.org/10.1152/physiol.2023.38.s1.5734697
