A network-based computational and experimental framework for repurposing compounds toward the treatment of non-alcoholic fatty liver disease

Autor: Zareifi, D.S. Chaliotis, O. Chala, N. Meimetis, N. Sofotasiou, M. Zeakis, K. Pantiora, E. Vezakis, A. Matsopoulos, G.K. Fragulidis, G. Alexopoulos, L.G.

Non-alcoholic fatty liver disease (NAFLD) is among the most common liver pathologies, however, none approved condition-specific therapy yet exists. The present study introduces a drug repositioning (DR) approach that combines in vitro steatosis model

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::e728658441ccc737d66e15c81f568be7
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3056185

Accurate SARS-CoV-2 seroprevalence surveys require robust multi-antigen assays

Autor: Fotis, C. Meimetis, N. Tsolakos, N. Politou, M. Akinosoglou, K. Pliaka, V. Minia, A. Terpos, E. Trougakos, I.P. Mentis, A. Marangos, M. Panayiotakopoulos, G. Dimopoulos, M.A. Gogos, C. Spyridonidis, A. Alexopoulos, L.G.

There is a plethora of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) serological tests based either on nucleocapsid phosphoprotein (N), S1-subunit of spike glycoprotein (S1) or receptor binding domain (RBD). Although these single-antig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::f60129a9ba21bc60269b5d2c3c37d460
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3056237

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Author Correction: AutoTransOP: translating omics signatures without orthologue requirements using deep learning.

Autor: Meimetis N; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Pullen KM; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Zhu DY; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Nilsson A; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, SE, 41296, Sweden., Hoang TN; School of Electrical Engineering and Computer Science, Washington State University, Pullman, WA, 99164-236, USA., Magliacane S; Institute of Informatics, University of Amsterdam, Amsterdam, The Netherlands.; MIT-IBM Watson AI Lab, Cambridge, MA, 02139, USA., Lauffenburger DA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. lauffen@mit.edu.

Publikováno v: NPJ systems biology and applications [NPJ Syst Biol Appl] 2024 Dec 13; Vol. 10 (1), pp. 148. Date of Electronic Publication: 2024 Dec 13.