Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Meili Hou"'
Autor:
Yi Tian, Yilin Liu, Jingpeng Han, Lei Liu, Han Luo, Meili Hou, Ruopeng Bai, Yu Lan, Baosheng Li
Publikováno v:
Organometallics. 41:3504-3513
Autor:
Meili Hou, Mengjie Ye, Lei Liu, Mingchuan Xu, Hongmei Liu, Hengbo Zhang, Yangfeng Li, Zhigang Xu, Baosheng Li
Publikováno v:
Molecular Pharmaceutics. 19:3279-3287
Fabrication of self-delivery drug systems can surmount low drug bioavailability and achieve a precise therapeutic process. In this study, a hydrogen sulfide-responsive (H
Autor:
Mingchuan Xu, Lei Liu, Tao Wang, Han Luo, Meili Hou, Luan Du, Xiaolan Xin, Qixing Lu, Baosheng Li
Publikováno v:
Organic Chemistry Frontiers. 9:1065-1069
A direct ring-opening/semipinacol rearrangement reaction catalyzed by the Brønsted acid of 4-(1-hydroxycyclobutyl)-1,2,3-triazole is reported, in which the usage of metal catalysts and the reservation of sulfonyl groups are avoided.
Publikováno v:
Chemistry – An Asian Journal. 14:3840-3844
Owing to the naturally high toxicity, poor water solubility, and other side effects of podophyllotoxin (PPT), its applications are limited. To address these issues, we developed a new PPT delivery system, in which the hydrophilic drug methotrexate (M
Autor:
Zhigang Xu, Yuejun Kang, Panpan Ma, Xiaoying Si, Lijun Ma, Bo Xiao, Meili Hou, Qiubing Chen, Jianglin Wang
Publikováno v:
Current Cancer Drug Targets. 19:304-311
Background: Oral administrations of microparticles (MPs) and nanoparticles (NPs) have been widely employed as therapeutic approaches for the treatment of ulcerative colitis (UC). However, no previous study has comparatively investigated the therapeut
Autor:
Shuang Bai, Peng Xue, Xiaoqian Ma, Meili Hou, Yuejun Kang, Yong-E Gao, Xiaoxiao Shi, Zhigang Xu
Publikováno v:
Carbohydrate Polymers. 182:235-244
We report a new reduction-responsive amphiphilic polymeric prodrug based on a linear dextran (DEX) backbone, which was conjugated with an hydrophobic camptothecin (CPT) prodrug block and an hydrophilic poly[poly(ethylene glycol) methyl ether methacry
Autor:
Peng Xue, Xiaoqian Ma, Jianjian Zhang, Zhigang Xu, Shuang Bai, Meili Hou, Baosheng Li, Xiaoxiao Shi, Tian Zhang, Yuejun Kang
Publikováno v:
Chemical Communications. 54:6252-6255
Fluorescent unimolecular micelles (FUMs) with multicolor emission acting as fluorescent nanoagents for optical fluorescence imaging have, for the first time, been reported. The FUMs show good water-solubility, ultra-small size, and enhanced biocompat
Autor:
Zhigang Xu, Meili Hou, Cangjie Yang, Xiaoqian Ma, Peng Xue, Shuang Bai, Chang Ming Li, Xiaoxiao Shi, Jiucun Chen, Yuejun Kang
Publikováno v:
Journal of Materials Chemistry B. 6:5549-5561
Nanomedicines based on unimolecular micelles (UMs) have shown unique advantages such as high micellar stability, programmed cargo delivery and enhanced therapeutic efficiency. Herein, we report an acid-activated amphiphilic prodrug based on a dextran
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 159:484-492
A stimuli-triggered drug release strategy could considerably reduce side effects while improving the bioavailability of chemotherapeutics. Here, we report that a series of ultra-pH-responsive copolymers are highly efficient drug delivery systems for
Publikováno v:
Tetrahedron Letters. 71:153044
To improve drug efficiency and reduce side effects in cancer therapy, precision therapy with small molecular prodrugs is urgently needed. Podophyllotoxin (PPT) is known as a chemotherapeutic drug. It is often designed as a prodrug to restrain adverse