Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Meilang, Xue"'
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 7, p 2030 (2024)
Endothelial Protein C Receptor (EPCR) is a key regulator of the activated protein C anti-coagulation pathway due to its role in the binding and activation of this protein. EPCR also binds to other ligands such as Factor VII and X, γδ T-cells, plasm
Externí odkaz:
https://doaj.org/article/d2745e8dbe994114bd72b2dcb89a43d7
Autor:
Meilang Xue, Christopher J. Jackson, Haiyan Lin, Ruilong Zhao, Hai Po H. Liang, Hartmut Weiler, John H. Griffin, Lyn March
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1255 (2024)
Endothelial protein C receptor (EPCR) is a receptor for the natural anti-coagulant activated protein C (aPC). It mediates the anti-inflammatory and barrier-protective functions of aPC through the cleavage of protease-activated receptor (PAR)1/2. Alle
Externí odkaz:
https://doaj.org/article/e08203ffcafc4f3191c95b87fadfeb7c
Autor:
Sohel M. Julovi, Kelly McKelvey, Nikita Minhas, Yee-Ka Agnes Chan, Meilang Xue, Christopher J. Jackson
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 370 (2023)
We previously reported that human keratinocytes express protease-activated receptor (PAR)-2 and play an important role in activated protein C (APC)-induced cutaneous wound healing. This study investigated the involvement of PAR-2 in the production of
Externí odkaz:
https://doaj.org/article/64a3978cb3124b2799dda6c030927416
Autor:
Christopher David Roche, Poonam Sharma, Anthony Wayne Ashton, Chris Jackson, Meilang Xue, Carmine Gentile
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Background3D bioprinting cardiac patches for epicardial transplantation are a promising approach for myocardial regeneration. Challenges remain such as quantifying printability, determining the ideal moment to transplant, and promoting vascularisatio
Externí odkaz:
https://doaj.org/article/0a4063a799e945c59203d3263ef41d8e
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 516 (2022)
Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with excessive inflammation and defective skin barrier function. Activated protein C (APC) is a natural anticoagulant with anti-inflammatory and barrier protective functions. Ho
Externí odkaz:
https://doaj.org/article/7be0045fdd394a47a1c8a2005dcc97ae
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10841 (2021)
The skin barrier is broadly composed of two elements—a physical barrier mostly localised in the epidermis, and an immune barrier localised in both the dermis and epidermis. These two systems interact cooperatively to maintain skin homeostasis and o
Externí odkaz:
https://doaj.org/article/451a17562a1144998bcbaf3d27610c3a
Autor:
Meilang Xue, Haiyan Lin, Helena Liang, Lara Bereza-Malcolm, Tom Lynch, Premarani Sinnathurai, Hartmut Weiler, Christopher Jackson, Lyn March
Publikováno v:
Rheumatology.
Objectives Endothelial protein C receptor (EPCR) is highly expressed in synovial tissues of patients with rheumatoid arthritis (RA), but the function of this receptor remains unknown in RA. This study investigated the effect of EPCR on the onset and
Autor:
John Vandervord, Christopher J. Jackson, Albert Kim, Thomas Charles Lang, Haiyan Lin, Meilang Xue, Aruna Wijewardana, Rachel T. McGrath, Gregory R. Fulcher, Duo Wang, Ruilong Zhao
Publikováno v:
European Burn Journal
Volume 2
Issue 4
Pages 17-237
Volume 2
Issue 4
Pages 17-237
The protein C (PC) system has proven to be a crucial cascade in systemic inflammatory and coagulopathic disorders such as severe sepsis and, more recently, in severe burns. We aimed to conflate our recent systemic findings with further investigations
Autor:
Christopher D. Roche, Haiyan Lin, Yizhou Huang, Charles E. de Bock, Dominik Beck, Meilang Xue, Carmine Gentile
Publikováno v:
Bioprinting. 30:e00263
Autor:
Susan M. Smith, Rodger Laurent, Anthony M. Sammel, Christopher B. Little, Elisabeth Karsten, Meilang Xue, Katherine Nguyen
Publikováno v:
International Journal of Rheumatic Diseases. 24:781-788
AIM Diagnosing and monitoring vascular activity in giant cell arteritis (GCA) is difficult due to the paucity of specific serological biomarkers. We assessed the utility of 8 novel biomarkers in an inception cohort of newly suspected GCA patients. ME