Výsledky vyhledávání - "Meike Simann"

Canonical FGFs Prevent Osteogenic Lineage Commitment and Differentiation of Human Bone Marrow Stromal Cells Via ERK1/2 Signaling

Autor: Meike, Simann, Solange, Le Blanc, Verena, Schneider, Viola, Zehe, Martin, Lüdemann, Norbert, Schütze, Franz, Jakob, Tatjana, Schilling

Publikováno v: Journal of cellular biochemistry. 118(2)

Controlling the adipo-osteogenic lineage decision of trabecular human bone marrow stromal cells (hBMSCs) in favor of osteogenesis represents a promising approach for osteoporosis therapy and prevention. Previously, Fibroblast Growth Factor 1 (FGF1) a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3e96179c139c0b70e2a366f296c9ef6b
https://pubmed.ncbi.nlm.nih.gov/27305863

Zobrazit plný text záznamu

Fibroblast growth factors 1 and 2 inhibit adipogenesis of human bone marrow stromal cells in 3D collagen gels

Autor: Franz Jakob, Meike Simann, Norbert Schütze, Tatjana Schilling, Solange Le Blanc

Publikováno v: Experimental cell research. 338(2)

Multipotent human bone marrow stromal cells (hBMSCs) are the common progenitors of osteoblasts and adipocytes. A shift in hBMSC differentiation in favor of adipogenesis may contribute to the bone loss and marrow fat accumulation observed in aging and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cabef72e6d523014df9d8e041b43f202
https://pubmed.ncbi.nlm.nih.gov/26384550

Zobrazit plný text záznamu

Heparin affects human bone marrow stromal cell fate: Promoting osteogenic and reducing adipogenic differentiation and conversion

Autor: Franz Jakob, Tatjana Schilling, Julia Dotterweich, Verena Schneider, Norbert Schütze, Solange Le Blanc, Viola Zehe, Meike Simann, Melanie Krug

Publikováno v: Bone. 78

Heparins are broadly used for the prevention and treatment of thrombosis and embolism. Yet, osteoporosis is considered to be a severe side effect in up to one third of all patients on long-term treatment. However, the mechanisms underlying this clini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8efd01787423ef030543977da3d704c2
https://pubmed.ncbi.nlm.nih.gov/25959412

Zobrazit plný text záznamu

Decrease of mineralization by FGF1 is linked to up-regulation of ANKH and OP in osteogenic differentiation and conversion

Autor: Solange LeBlanc, Tatjana Schilling, Franz Jakob, Meike Simann, Norbert Schütze

Publikováno v: Bone Abstracts.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d31d50e675f639edf19762292c8b12dc
https://doi.org/10.1530/boneabs.3.pp130

Zobrazit plný text záznamu

Quality of Cell Products: Authenticity, Identity, Genomic Stability and Status of Differentiation

Autor: Meike Simann, Wilhelm G. Dirks, Werner Lindenmaier, Konstantin Miller, Kurt E.J. Dittmar, Oliver Schön, Wilhelm Meyring, Henk S.P. Garritsen, Horst Hannig, N. Zghoul, Lars Macke

Publikováno v: Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie. 37(2)

Cellular therapies that either use modifications of a patient's own cells or allogeneic cell lines are becoming in vogue. Besides the technical issues of optimal isolation, cultivation and modification, quality control of the generated cellular produ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abcd32e69bac626c4de6a5299b13db74
https://pubmed.ncbi.nlm.nih.gov/20737047

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání