Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Meike Paschen"'
Autor:
Barbara Leibiger, Tilo Moede, Ismael Valladolid-Acebes, Meike Paschen, Montse Visa, Ingo B. Leibiger, Per-Olof Berggren
Publikováno v:
Metabolites, Vol 11, Iss 6, p 387 (2021)
The pancreatic islets of Langerhans consist of endocrine cells that secrete peptide hormones into the blood circulation in response to metabolic stimuli. When transplanted into the anterior chamber of the eye (ACE), pancreatic islets engraft and main
Externí odkaz:
https://doaj.org/article/6669e463aece4bb4b111a710db503a85
Autor:
Barbara Leibiger, Tilo Moede, Meike Paschen, Na-Oh Yunn, Jong Hoon Lim, Sung Ho Ryu, Teresa Pereira, Per-Olof Berggren, Ingo B. Leibiger
Publikováno v:
Cell Reports, Vol 13, Iss 1, Pp 15-22 (2015)
Insulin resistance is a syndrome that affects multiple insulin target tissues, each having different biological functions regulated by insulin. A remaining question is to mechanistically explain how an insulin target cell/tissue can be insulin resist
Externí odkaz:
https://doaj.org/article/579433b1afa946ba860b86f60e89c2ef
Autor:
Ingo B. Leibiger, Noah Moruzzi, Ismael Valladolid-Acebes, Meike Paschen, Per Olof Berggren, Barbara Leibiger, Francesca Lazzeri‐Barcelo, Tilo Moede
Publikováno v:
Journal of Cellular and Molecular Medicine
The two insulin receptor (IR) isoforms IR‐A and IR‐B are responsible for the pleiotropic actions of insulin and insulin‐like growth factors. Consequently, changes in IR isoform expression and in the bioavailability of their ligands will impact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63e356df8a2baab604f119f8365f050d
https://doi.org/10.1111/jcmm.16452
https://doi.org/10.1111/jcmm.16452
Autor:
Carina Ämmälä, Barbara Leibiger, Aparna Neelakandhan, Adelinn Biernath, Ismael Valladolid-Acebes, Meike Paschen, Joan Mir-Coll, Burcak Yesildag, Ingo B. Leibiger, Per Olof Berggren, Tilo Moede
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1813, p 1813 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences
Volume 22
Issue 4
Loss of pancreatic β-cell function is a critical event in the pathophysiology of type 2 diabetes. However, studies of its underlying mechanisms as well as the discovery of novel targets and therapies have been hindered due to limitations in availabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60eb83116f49e14502870ab0c81c270c
https://www.mdpi.com/1422-0067/22/4/1813
https://www.mdpi.com/1422-0067/22/4/1813
Autor:
Meike Paschen, Ingo B. Leibiger, Barbara Leibiger, Kerstin Brismar, Stefan Jacob, Concha F. García-Prieto, Noah Moruzzi, Per Olof Berggren, Tilo Moede, Ismael Valladolid-Acebes
Publikováno v:
The FASEB Journal
Although convincing in genetic models, the relevance of β-cell insulin resistance in diet-induced type 2 diabetes (T2DM) remains unclear. Exemplified by diabetes-prone, male, C57B1/6J mice being fed different combinations of Western-style diet, we s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f61cdcab9663121cd3e20f8f4de922f
http://europepmc.org/articles/PMC6355083
http://europepmc.org/articles/PMC6355083
Autor:
Sung Ho Ryu, Na Oh Yunn, Ingo B. Leibiger, Per Olof Berggren, Barbara Leibiger, Teresa Pereira, Jong Hoon Lim, Meike Paschen, Tilo Moede
Publikováno v:
Cell Reports, Vol 13, Iss 1, Pp 15-22 (2015)
Insulin resistance is a syndrome that affects multiple insulin target tissues, each having different biological functions regulated by insulin. A remaining question is to mechanistically explain how an insulin target cell/tissue can be insulin resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fdb43edcbcfb438af9f382d756735b6
http://www.sciencedirect.com/science/article/pii/S2211124715009559
http://www.sciencedirect.com/science/article/pii/S2211124715009559
Autor:
Meike Paschen, Per Olof Berggren, Ingo B. Leibiger, Barbara Leibiger, Galyna Bryzgalova, Stefan Jacob, Tilo Moede
Publikováno v:
Scientific Reports
Insulin resistance contributes to the development of cardio-vascular disease and diabetes. An important but unresolved task is to study the dynamics of insulin resistance in selective cell types of insulin target tissues in vivo. Here we present a no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aeef2d05e1e89a551403835456b1c7f
https://doi.org/10.1038/srep21448
https://doi.org/10.1038/srep21448
Autor:
Vanessa Shi Yun Tay, Martin Köhler, Karin Åvall, Mark J. Graham, Lars Selander, Stefan K. Nilsson, Barbara Leibiger, Rosanne M. Crooke, Essam Refai, Midhat H. Abdulreda, Lisa Juntti-Berggren, Per Olof Berggren, Elisabetta Daré, Yusuf Ali, Stefan Jacob, Andrea Dicker, Erwin Ilegems, Ingo B. Leibiger, Tilo Moede, Meike Paschen
Publikováno v:
Proceedings of the National Academy of Sciences. 112
Insulin resistance and β-cell failure are the major defects in type 2 diabetes mellitus. However, the molecular mechanisms linking these two defects remain unknown. Elevated levels of apolipoprotein CIII (apoCIII) are associated not only with insuli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9e79cb6a3f150326c2e3d302f36412
https://doi.org/10.1073/pnas.1423849112
https://doi.org/10.1073/pnas.1423849112