Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Meike Lüdemann"'
Autor:
Renate Lüllmann-Rauch, Markus Damme, Annika Ericsson, Judith Blanz, Paul Saftig, Michelle Rothaug, Rudi D'Hooge, Claes Andersson, Jens Fogh, Hans Christian Beck, Meike Lüdemann, Stijn Stroobants
Publikováno v:
Damme, M, Stroobants, S, Lüdemann, M, Rothaug, M, Lüllmann-Rauch, R, Beck, H C, Ericsson, A, Andersson, C, Fogh, J, D’Hooge, R, Saftig, P & Blanz, J 2015, ' Chronic enzyme replacement therapy ameliorates neuropathology in alpha-mannosidosis mice ', Annals of Clinical and Translational Neurology, vol. 2, no. 11, pp. 987-1001 . https://doi.org/10.1002/acn3.245
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology
OBJECTIVE: The lysosomal storage disease alpha-mannosidosis is caused by the deficiency of the lysosomal acid hydrolase alpha-mannosidase (LAMAN) leading to lysosomal accumulation of neutral mannose-linked oligosaccharides throughout the body, includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cafe9edce6c251b2c9548ef01ec5d45
https://doi.org/10.1002/acn3.245
https://doi.org/10.1002/acn3.245
Autor:
Stijn Stroobants, Paul Saftig, Renate Lüllmann-Rauch, Claes Andersson, Rudi D'Hooge, Meike Lüdemann, Jens Fogh, Willy Morelle, Judith Blanz, Helena Reuterwall, Jean Claude Michalski
Publikováno v:
Human Molecular Genetics. 17:3437-3445
Despite the progress in the treatment of lysosomal storage disorders (LSDs) mainly by enzyme replacement therapy, only limited success was reported in targeting the appropriate lysosomal enzyme into the brain. This prevents efficient clearance of neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51acf80c245b71f8984f1039a0421e08
https://doi.org/10.1093/hmg/ddn237
https://doi.org/10.1093/hmg/ddn237