Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Meik Kunz"'
Autor:
Tim Roehnisch, Mari Carmen Martos-Contreras, Mehdi Manoochehri, Mauro Nogueira, Franziska Bremm, Jan Dörrie, Jan Christoph, Meik Kunz, Wolfgang Schönharting
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
This report details a case of pancreatic cancer with liver metastasis that exhibited a positive immune response to personalized immunization therapy. Our study involved the identification of neoantigens and their corresponding immunogenic peptides us
Externí odkaz:
https://doaj.org/article/32b4c167178f42979e1b0e52467fb80f
Autor:
Elisabeth Naschberger, Maximilian Fuchs, Nicholas Dickel, Meik Kunz, Bernt Popp, Charles Gwellem Anchang, Richard Demmler, Yanmin Lyu, Steffen Uebe, Arif Bülent Ekici, Carol Immanuel Geppert, Arndt Hartmann, Christian Flierl, Katja Petter, Tobias Gass, Simon Völkl, Michael Scharl, Andreas Ramming, Claudia Günther, Susanne Merkel, Vera Simone Schellerer, Michael Stürzl
Publikováno v:
Cancer Communications, Vol 43, Iss 11, Pp 1280-1285 (2023)
Externí odkaz:
https://doaj.org/article/b5897fea14a54e958b01f425353926f6
Autor:
Katrin Peckert-Maier, Andreas B. Wild, Laura Sprißler, Maximilian Fuchs, Philipp Beck, Jean-Philippe Auger, Pia Sinner, Astrid Strack, Petra Mühl-Zürbes, Ntilek Ramadan, Meik Kunz, Gerhard Krönke, Lena Stich, Alexander Steinkasserer, Dmytro Royzman
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Alterations in macrophage (Mφ) polarization, function, and metabolic signature can foster development of chronic diseases, such as autoimmunity or fibrotic tissue remodeling. Thus, identification of novel therapeutic agents that modulate human Mφ b
Externí odkaz:
https://doaj.org/article/ebaecb1fe44b410fa7de1e8626ca690e
Autor:
Dmytro Royzman, Katrin Peckert-Maier, Lena Stich, Christina König, Andreas B. Wild, Miyuki Tauchi, Christian Ostalecki, Franklin Kiesewetter, Stefan Seyferth, Geoffrey Lee, Sabine A. Eming, Maximilian Fuchs, Meik Kunz, Ewa K. Stürmer, Eva M. J. Peters, Carola Berking, Elisabeth Zinser, Alexander Steinkasserer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
To facilitate the recovery process of chronic and hard-to-heal wounds novel pro-resolving treatment options are urgently needed. We investigated the pro-regenerative properties of soluble CD83 (sCD83) on cutaneous wound healing, where sCD83 accelerat
Externí odkaz:
https://doaj.org/article/1c5189c1d0044a92a854191e8b60e1a3
Autor:
Stevan D. Stojanović, Maximilian Fuchs, Chunguang Liang, Kevin Schmidt, Ke Xiao, Annette Just, Angelika Pfanne, Andreas Pich, Gregor Warnecke, Peter Braubach, Christina Petzold, Danny Jonigk, Jörg H. W. Distler, Jan Fiedler, Thomas Thum, Meik Kunz
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract The family of RNA-binding proteins (RBP) functions as a crucial regulator of multiple biological processes and diseases. However, RBP function in the clinical setting of idiopathic pulmonary fibrosis (IPF) is still unknown. We developed a pr
Externí odkaz:
https://doaj.org/article/757334abd2ab4df69064526720aa8b80
Autor:
Dmytro Royzman, Darja Andreev, Lena Stich, Katrin Peckert-Maier, Andreas B. Wild, Elisabeth Zinser, Petra Mühl-Zürbes, Evan Jones, Susanne Adam, Silke Frey, Maximilian Fuchs, Meik Kunz, Tobias Bäuerle, Lisa Nagel, Georg Schett, Aline Bozec, Alexander Steinkasserer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Here we show that soluble CD83 induces the resolution of inflammation in an antigen-induced arthritis (AIA) model. Joint swelling and the arthritis-related expression levels of IL-1β, IL-6, RANKL, MMP9, and OC-Stamp were strongly reduced, while Foxp
Externí odkaz:
https://doaj.org/article/576ad5b73c124cb0990703d4d392cc97
Autor:
Arne Schmidt, Maximilian Fuchs, Stevan D. Stojanović, Chunguang Liang, Kevin Schmidt, Mira Jung, Ke Xiao, Jan Weusthoff, Annette Just, Angelika Pfanne, Jörg H. W. Distler, Thomas Dandekar, Jan Fiedler, Thomas Thum, Meik Kunz
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundConstant supply of oxygen is crucial for multicellular tissue homeostasis and energy metabolism in cardiac tissue. As a first response to acute hypoxia, endothelial cells (ECs) promote recruitment and adherence of immune cells to the dysbal
Externí odkaz:
https://doaj.org/article/d9a651f1db284f5493baf7e4bc10f6af
Autor:
Wolfgang Schönharting, Tim Roehnisch, Mehdi Manoochehri, Jan Christoph, Marie Sieger, Mauro Nogueira, Mari Carmen Martos-Contreras, Meik Kunz
Publikováno v:
Vaccines, Vol 11, Iss 6, p 1023 (2023)
Cancer neoantigens that arise from somatic mutations have emerged as important targets for personalized immunization. Here, we report an improved overall survival of a HER2-positive metastatic breast cancer patient using a bioinformatic-based persona
Externí odkaz:
https://doaj.org/article/50cbc605f628487bbedcd33ae9e1ecfa
Autor:
Juliane März, Max Kurlbaum, Oisin Roche-Lancaster, Timo Deutschbein, Mirko Peitzsch, Cornelia Prehn, Dirk Weismann, Mercedes Robledo, Jerzy Adamski, Martin Fassnacht, Meik Kunz, Matthias Kroiss
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
ContextPheochromocytomas and paragangliomas (PPGL) cause catecholamine excess leading to a characteristic clinical phenotype. Intra-individual changes at metabolome level have been described after surgical PPGL removal. The value of metabolomics for
Externí odkaz:
https://doaj.org/article/e39dfe42b66b4b66a1834875d69cf9dc
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Inflammatory bowel disease describes chronic inflammatory disorders. The incidence of the disease is rising. A major step in disease development is the breakdown of the epithelial cell barrier. Numerous blood vessels are directly located underneath t
Externí odkaz:
https://doaj.org/article/1ce5b47548c44dc58b47fd8c924cf81a