Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Meijun Z. Lundberg"'
Autor:
Wen-Bin Ou, Meijun Z. Lundberg, Shuihao Zhu, Nacef Bahri, Anastasios Kyriazoglou, Liangliang Xu, Ting Chen, Adrian Mariño-Enriquez, Jonathan A. Fletcher
Publikováno v:
Oncogenesis, Vol 10, Iss 5, Pp 1-9 (2021)
Abstract Endometrial stromal sarcoma (ESS) is the second most common subtype of uterine mesenchymal cancer, after leiomyosarcoma, and oncogenic fusion proteins are found in many ESS. Our previous studies demonstrated transforming properties and diagn
Externí odkaz:
https://doaj.org/article/895d9a80b1a14ec68af5a84662df19cf
Autor:
Inga-Marie Schaefer, Matthew L. Hemming, Meijun Z. Lundberg, Matthew P. Serrata, Isabel Goldaracena, Ninning Liu, Peng Yin, Joao A. Paulo, Steven P. Gygi, Suzanne George, Jeffrey A. Morgan, Monica M. Bertagnolli, Ewa T. Sicinska, Chen Chu, Shanshan Zheng, Adrian Mariño-Enríquez, Jason L. Hornick, Chandrajit P. Raut, Wen-Bin Ou, George D. Demetri, Sinem K. Saka, Jonathan A. Fletcher
Publikováno v:
British Journal of Cancer. 127:2072-2085
Advanced gastrointestinal stromal tumour (GIST) is characterised by genomic perturbations of key cell cycle regulators. Oncogenic activation of CDK4/6 results in RB1 inactivation and cell cycle progression. Given that single-agent CDK4/6 inhibitor th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99728f31140a073b466bed2211d43e19
https://doi.org/10.1038/s41416-022-01990-5
https://doi.org/10.1038/s41416-022-01990-5
Autor:
Jonathan A. Fletcher, Liangliang Xu, Ting Chen, Wen-Bin Ou, Nacef Bahri, Meijun Z. Lundberg, Adrián Mariño-Enríquez, Anastasios Kyriazoglou, Shuihao Zhu
Publikováno v:
Oncogenesis, Vol 10, Iss 5, Pp 1-9 (2021)
Oncogenesis
Oncogenesis
Endometrial stromal sarcoma (ESS) is the second most common subtype of uterine mesenchymal cancer, after leiomyosarcoma, and oncogenic fusion proteins are found in many ESS. Our previous studies demonstrated transforming properties and diagnostic rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c153907e2f6d952648d7e15def840b
https://doaj.org/article/895d9a80b1a14ec68af5a84662df19cf
https://doaj.org/article/895d9a80b1a14ec68af5a84662df19cf
Autor:
Inga-Marie Schaefer, Matthew L. Hemming, Meijun Z. Lundberg, Matthew P. Serrata, Isabel Goldaracena, Ninning Liu, Peng Yin, Joao A. Paulo, Steven P. Gygi, Suzanne George, Jeffrey A. Morgan, Monica M. Bertagnolli, Ewa T. Sicinska, Adrian Mariño-Enríquez, Jason L. Hornick, Chandrajit P. Raut, George D. Demetri, Wen-Bin Ou, Sinem K. Saka, Jonathan A. Fletcher
Publikováno v:
Clinical Cancer Research. 28:A013-A013
Advanced GIST is characterized by genomic perturbations of key cell cycle regulators. Oncogenic activation of CDK4/6 results in RB1 inactivation and cell cycle progression. Given that single-agent CDK4/6 inhibitor (CDK4/6i) therapy failed to show cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e67df8021f6ef404e7df3593d76a2a6a
https://doi.org/10.1158/1557-3265.sarcomas22-a013
https://doi.org/10.1158/1557-3265.sarcomas22-a013
Autor:
Inga-Marie Schaefer, Meijun Z. Lundberg, Matthew L. Hemming, Sinem K. Saka, Matthew P. Serrata, Isabel Goldaracena, Ninning Liu, Peng Yin, Joao A. Paulo, Steven Gygi, George D. Demetri, Ewa Sicinska, Adrian Mariño-Enríquez, Jason L. Hornick, Chandrajit P. Raut, Wen-Bin Ou, Jonathan A. Fletcher
Publikováno v:
Cancer Research. 82:5648-5648
Gastrointestinal stromal tumor (GIST) is the most common GI sarcoma and is generally initiated by KIT or PDGFRA mutations which are compelling therapeutic targets for tyrosine kinase inhibitors (TKI). However, the emergence of secondary mutations res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7578e742f8444f94b6cccf6aeb739722
https://doi.org/10.1158/1538-7445.am2022-5648
https://doi.org/10.1158/1538-7445.am2022-5648
Autor:
Sebastian Bauer, Wei-Lien Wang, Jonathan A. Fletcher, Davis R. Ingram, Inga-Marie Schaefer, Matt van de Rijn, Elizabeth G Demicco, Alexander J. Lazar, Meijun Z. Lundberg, Laurence H. Baker, Magdalena Matusiak, Joanna Przybyl, Jason L. Hornick, Adrián Mariño-Enríquez, Frédéric Chibon
Publikováno v:
Cancer
BACKGROUND: Leiomyosarcoma (LMS) is the most common soft tissue and uterine sarcoma, but no standard therapy is available for recurrent or metastatic LMS. TP53, p16/RB1, and PI3K/mTOR pathway dysregulations are recurrent events, and some LMS express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51fbef4f8083e91182e44ae01be98d3a
https://pubmed.ncbi.nlm.nih.gov/33788262
https://pubmed.ncbi.nlm.nih.gov/33788262