Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Meijun, Si"'
Autor:
Hongchun Lin, Hui Peng, Yuxiang Sun, Meijun Si, Jiao Wu, Yanlin Wang, Sandhya S. Thomas, Zheng Sun, Zhaoyong Hu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract A comprehensive atlas of cis-regulatory elements and their dynamic activity is necessary to understand the transcriptional basis of cellular structure maintenance, metabolism, and responses to the environment. Here we show, using matched sin
Externí odkaz:
https://doaj.org/article/c86830292466481f874cfda853c81584
Autor:
Yuewen Luo, Xiantao Zhang, Ran Chen, Rong Li, Yang Liu, Junsong Zhang, Qin liu, Meijun Si, Jun Liu, Bolin Wu, Xuemei Wang, Shijian Wu, Yiwen Zhang, Xu Zhang, Deyin Guo, Xin He, Ting Pan, Hui Zhang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-15 (2022)
Abstract Activation-induced cytidine deaminase (AID) initiates class-switch recombination and somatic hypermutation (SHM) in antibody genes. Protein expression and activity are tightly controlled by various mechanisms. However, it remains unknown whe
Externí odkaz:
https://doaj.org/article/96ef8a1d3cc04e908e9202a402f6c0e5
Autor:
Wanshan Du, Cai-Yue Gao, Xing You, Liang Li, Zhi-Bin Zhao, Mengting Fang, Zhiming Ye, Meijun Si, Zhe-Xiong Lian, Xueqing Yu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IgA nephropathy (IgAN) is the most common primary glomerulonephritis, characterized by glomerular deposition of IgA immune complexes, mainly produced by B cells under the regulation of CD4+T cells. However, the alterations of specific CD4+T cell subs
Externí odkaz:
https://doaj.org/article/6f0c37540c0945dc8283aa4b81456e87
Autor:
Yuhua Zhang, Xingchen Zhao, Cuili Li, Yan Yang, Luan Li, Yingwen Chen, Qingying Shi, Zhilian Li, Yanhua Wu, Li Zhang, Ruizhao Li, Meijun Si, Xinling Liang, Yuanhan Chen
Publikováno v:
Biochemical and Biophysical Research Communications. 643:61-68
Nicotinamide adenine dinucleotide (NAD) is an essential coenzyme in the kidney. The first step in de novo NAD synthesis is regulated by indoleamine 2,3-dioxygenase (IDO), a tryptophan-catabolizing enzyme. Here, we investigated NAD synthetic flux and
Autor:
Lijing Sun, Meijun Si, Xinyan Liu, Jong Min Choi, Yanlin Wang, Sandhya S. Thomas, Hui Peng, Zhaoyong Hu
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 9, Iss 5, Pp 962-974 (2018)
Abstract Background Chronic kidney disease (CKD) is commonly associated with cachexia, a condition that causes skeletal muscle wasting and an unfavourable prognosis. Although mechanisms leading to cachexia have been intensively studied, the advance o
Externí odkaz:
https://doaj.org/article/a76b9170fe9544b88b907ee96004d212
Autor:
Sandhya S. Thomas, Lijing Sun, Xinyan Liu, Yanlin Wang, Zhaoyong Hu, Meijun Si, Jong Min Choi, Hui Peng
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle. 9:962-974
BACKGROUND Chronic kidney disease (CKD) is commonly associated with cachexia, a condition that causes skeletal muscle wasting and an unfavourable prognosis. Although mechanisms leading to cachexia have been intensively studied, the advance of biologi
Autor:
Xianrui Dou, Wenbo Zhao, Zhaoyong Hu, Yin Li, Jun Liu, Tanqi Lou, Hongchun Lin, Qianqian Wang, Yong Huang, Meijun Si, Hui Zhang, Dan Luo, Hui Peng
Publikováno v:
Science Translational Medicine. 11
Progressive peritoneal fibrosis affects patients receiving peritoneal dialysis (PD) and has no reliable treatment. The mechanisms that initiate and sustain peritoneal fibrosis remain incompletely elucidated. To overcome these problems, we developed a
Publikováno v:
BMJ Case Rep
Ethambutol (EMB) and isoniazid (INH) are the first-line antituberculosis (anti-TB) drugs. However, their neurotoxicity could cause adverse effect and the patients with end-stage renal disease are especially vulnerable due to the reduction in renal dr
Publikováno v:
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi. 28(6)
The aim of this study is to investigate the growth and proliferation of bone marrow mesenchymal stem cells (BMSCs) three-dimensionally cultured in Pluronic F-127 gel, in order to explore the cellular compatibility of gel and to investigate the feasib