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Pharmacologic targeting of renal ischemia-reperfusion injury using a normothermic machine perfusion platform.

Autor: Hameed AM; Department of Surgery, Westmead Hospital, Sydney, Australia.; Westmead Institute for Medical Research, Sydney, Australia.; Sydney Medical School, University of Sydney, Sydney, Australia., Lu DB; Westmead Institute for Medical Research, Sydney, Australia., Burns H; Westmead Institute for Medical Research, Sydney, Australia., Byrne N; Westmead Institute for Medical Research, Sydney, Australia., Chew YV; Westmead Institute for Medical Research, Sydney, Australia., Julovi S; Westmead Institute for Medical Research, Sydney, Australia., Ghimire K; Westmead Institute for Medical Research, Sydney, Australia., Zanjani NT; Westmead Institute for Medical Research, Sydney, Australia., P'ng CH; Institute for Clinical Pathology and Medical Research, Westmead Hospital, Sydney, Australia., Meijles D; St George's, University of London, London, UK., Dervish S; Westmead Institute for Medical Research, Sydney, Australia., Matthews R; Department of Animal Care, Westmead Hospital, Sydney, Australia., Miraziz R; Department of Anesthesia, Westmead Hospital, Sydney, Australia., O'Grady G; Department of Surgery, The University of Auckland, Auckland, New Zealand., Yuen L; Department of Surgery, Westmead Hospital, Sydney, Australia.; Sydney Medical School, University of Sydney, Sydney, Australia., Pleass HC; Department of Surgery, Westmead Hospital, Sydney, Australia.; Sydney Medical School, University of Sydney, Sydney, Australia., Rogers NM; Westmead Institute for Medical Research, Sydney, Australia. natasha.rogers@sydney.edu.au.; Sydney Medical School, University of Sydney, Sydney, Australia. natasha.rogers@sydney.edu.au.; Department of Transplant/Renal Medicine, Westmead Hospital, Sydney, Australia. natasha.rogers@sydney.edu.au., Hawthorne WJ; Department of Surgery, Westmead Hospital, Sydney, Australia. wayne.hawthorne@sydney.edu.au.; Westmead Institute for Medical Research, Sydney, Australia. wayne.hawthorne@sydney.edu.au.; Sydney Medical School, University of Sydney, Sydney, Australia. wayne.hawthorne@sydney.edu.au.

Publikováno v: Scientific reports [Sci Rep] 2020 Apr 24; Vol. 10 (1), pp. 6930. Date of Electronic Publication: 2020 Apr 24.

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Akademický článek

The alarmin, interleukin-33, increases vascular tone via extracellular signal regulated kinase-mediated Ca ²⁺ sensitization and endothelial nitric oxide synthase inhibition.

Autor: DeVallance E; Department of Physiology, Pharmacology & Toxicology, Health Sciences Center, West Virginia University, Morgantown, WV, USA.; Center for Inhalation Toxicology, West Virginia University School of Medicine, Morgantown, WV, USA., Bowdridge E; Department of Physiology, Pharmacology & Toxicology, Health Sciences Center, West Virginia University, Morgantown, WV, USA.; Center for Inhalation Toxicology, West Virginia University School of Medicine, Morgantown, WV, USA., Garner K; Department of Physiology, Pharmacology & Toxicology, Health Sciences Center, West Virginia University, Morgantown, WV, USA.; Center for Inhalation Toxicology, West Virginia University School of Medicine, Morgantown, WV, USA., Griffith J; Department of Physiology, Pharmacology & Toxicology, Health Sciences Center, West Virginia University, Morgantown, WV, USA.; Center for Inhalation Toxicology, West Virginia University School of Medicine, Morgantown, WV, USA., Seman M; Department of Physiology, Pharmacology & Toxicology, Health Sciences Center, West Virginia University, Morgantown, WV, USA., Batchelor T; Department of Physiology, Pharmacology & Toxicology, Health Sciences Center, West Virginia University, Morgantown, WV, USA.; Center for Inhalation Toxicology, West Virginia University School of Medicine, Morgantown, WV, USA., Velayutham M; Department of Biochemistry and Molecular Medicine, Health Sciences Center, West Virginia University, Morgantown, WV, USA., Goldsmith WT; Department of Physiology, Pharmacology & Toxicology, Health Sciences Center, West Virginia University, Morgantown, WV, USA.; Center for Inhalation Toxicology, West Virginia University School of Medicine, Morgantown, WV, USA., Hussain S; Department of Physiology, Pharmacology & Toxicology, Health Sciences Center, West Virginia University, Morgantown, WV, USA.; Center for Inhalation Toxicology, West Virginia University School of Medicine, Morgantown, WV, USA., Kelley EE; Department of Physiology, Pharmacology & Toxicology, Health Sciences Center, West Virginia University, Morgantown, WV, USA.; Center for Inhalation Toxicology, West Virginia University School of Medicine, Morgantown, WV, USA., Nurkiewicz TR; Department of Physiology, Pharmacology & Toxicology, Health Sciences Center, West Virginia University, Morgantown, WV, USA.; Center for Inhalation Toxicology, West Virginia University School of Medicine, Morgantown, WV, USA.

Publikováno v: The Journal of physiology [J Physiol] 2024 Nov; Vol. 602 (22), pp. 6087-6107. Date of Electronic Publication: 2024 Nov 14.

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Akademický článek

Vascular TSP1-CD47 signaling promotes sickle cell-associated arterial vasculopathy and pulmonary hypertension in mice.

Autor: Novelli EM; Heart, Lung, Blood, and Vascular Medicine Institute and Division of Hematology/Oncology, UPMC Department of Medicine, University of Pittsburgh , Pittsburgh, Pennsylvania., Little-Ihrig L; Heart, Lung, Blood, and Vascular Medicine Institute and Division of Hematology/Oncology, UPMC Department of Medicine, University of Pittsburgh , Pittsburgh, Pennsylvania., Knupp HE; UPMC Children's Hospital of Pittsburgh , Pittsburgh, Pennsylvania., Rogers NM; Department of Medicine, Westmead Clinical School, University of Sydney , Sydney, New South Wales , Australia., Yao M; Department of Pharmaceutical Science, Midwestern University , Glendale, Arizona., Baust JJ; Heart, Lung, Blood, and Vascular Medicine Institute and Division of Hematology/Oncology, UPMC Department of Medicine, University of Pittsburgh , Pittsburgh, Pennsylvania., Meijles D; School of Biological Sciences, University of Reading , Reading , United Kingdom., St Croix CM; Center for Biologic Imaging, University of Pittsburgh , Pittsburgh, Pennsylvania., Ross MA; Center for Biologic Imaging, University of Pittsburgh , Pittsburgh, Pennsylvania., Pagano PJ; Heart, Lung, Blood, and Vascular Medicine Institute and Division of Hematology/Oncology, UPMC Department of Medicine, University of Pittsburgh , Pittsburgh, Pennsylvania., DeVallance ER; Heart, Lung, Blood, and Vascular Medicine Institute and Division of Hematology/Oncology, UPMC Department of Medicine, University of Pittsburgh , Pittsburgh, Pennsylvania., Miles G; Department of Molecular and Human Genetics, Baylor College of Medicine , Houston, Texas., Potoka KP; Heart, Lung, Blood, and Vascular Medicine Institute and Division of Hematology/Oncology, UPMC Department of Medicine, University of Pittsburgh , Pittsburgh, Pennsylvania.; UPMC Children's Hospital of Pittsburgh , Pittsburgh, Pennsylvania., Isenberg JS; Heart, Lung, Blood, and Vascular Medicine Institute and Division of Hematology/Oncology, UPMC Department of Medicine, University of Pittsburgh , Pittsburgh, Pennsylvania., Gladwin MT; Heart, Lung, Blood, and Vascular Medicine Institute and Division of Hematology/Oncology, UPMC Department of Medicine, University of Pittsburgh , Pittsburgh, Pennsylvania.

Publikováno v: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2019 Jun 01; Vol. 316 (6), pp. L1150-L1164. Date of Electronic Publication: 2019 Mar 20.

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