Shen-Zhi-Ling oral liquid ameliorates cerebral glucose metabolism disorder in early AD via insulin signal transduction pathway in vivo and in vitro

Autor: Gaofeng Qin, Yunfang Dong, Zhenhong Liu, Zhuoyan Gong, Chenyan Gao, Mingcui Zheng, Meijing Tian, Yannan He, Liqun Zhong, Pengwen Wang

Publikováno v: Chinese Medicine, Vol 16, Iss 1, Pp 1-19 (2021)

Abstract Background Shen-Zhi-Ling oral liquid (SZL) is an herbal formula known for its efficacy of nourishing “heart and spleen”, and is used for the treatment and prevention of middle- and early-stage dementia. This study investigated the effect

Externí odkaz: https://doaj.org/article/79db202da7114cc9863f3133d9d29846

Banxia Xiexin Decoction Ameliorates Cognition Deficits by Activating Autophagy-induced Clearance of Aβ in APP/PS1 Mice

Autor: Chenyan Gao, Zhuoyan Gong, Meijing Tian, Gaofeng Qin, Mingcui Zheng, Yannan He, Pengwen Wang

The purpose of this study aimed to explore the potential mechanism of the Chinese herbal compound Banxia Xiexin decoction (BXD) concerning autophagy in the treatment of Alzheimer’s disease (AD). Amyloid-β (Aβ) clearance of AD mice is weakened by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::56fb2f3c0bc0382a30fb401bfe4b84ba
https://doi.org/10.21203/rs.3.rs-1574557/v1

Shenzhiling oral liquid protects the myelin sheath against Alzheimer's disease through the PI3K/Akt-mTOR pathway

Autor: Shuaiyang Huang, Zhenhong Liu, Mingcui Zheng, Zhuoyan Gong, Gaofeng Qin, Yannan He, Meijing Tian, Lulu Mana, Pengwen Wang

Publikováno v: Journal of ethnopharmacology. 278

Ethnopharmacological relevance Shenzhiling oral liquid (SZL), a traditional Chinese medicine (TCM) compound, is firstly approved by the Chinese Food and Drug Administration (CFDA) for the treatment of mild to moderate Alzheimer's disease (AD). SZL is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2fa43bc7d88ec560c1070cfbf28d31
https://pubmed.ncbi.nlm.nih.gov/34082015

Chinese herbal compound Jinsiwei improves synaptic plasticity in mice with sporadic Alzheimer's disease induced by streptozotocin.

Autor: Meijing T; Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China., Yannan HE; Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China., Mingcui Z; Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China., Gaofeng Q; Department of Traditional Chinese Medicine, Affiliated Hospital of Binzhou Medical College, Shandong 256603, China., Zhuoyan G; Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China., Shuaiyang H; Department of Respiratory Medicine, the Third Affiliated Hospital of Beijing University of Chinese Medicine, Beijing 100029, China., Pengwen W; Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China.

Publikováno v: Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan [J Tradit Chin Med] 2023 Feb; Vol. 43 (1), pp. 78-86.