Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Meiji, Itakura"'
Autor:
Yuya Terashima, Etsuko Toda, Meiji Itakura, Mikiya Otsuji, Sosuke Yoshinaga, Kazuhiro Okumura, Francis H. W. Shand, Yoshihiro Komohara, Mitsuhiro Takeda, Kana Kokubo, Ming-Chen Chen, Sana Yokoi, Hirofumi Rokutan, Yutaka Kofuku, Koji Ohnishi, Miki Ohira, Toshihiko Iizasa, Hirofumi Nakano, Takayoshi Okabe, Hirotatsu Kojima, Akira Shimizu, Shiro Kanegasaki, Ming-Rong Zhang, Ichio Shimada, Hiroki Nagase, Hiroaki Terasawa, Kouji Matsushima
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The cytoplasmic protein FROUNT can bind to chemokine receptors and enhance chemokine signalling. Here, the authors show that inhibiting FROUNT in macrophages either by knockdown of the gene or using the anti-alcoholism drug disulfiram, results in a r
Externí odkaz:
https://doaj.org/article/a4d75cebbb8f47a985d666129063bb6d
Autor:
Sana Yokoi, Takayoshi Okabe, Ichio Shimada, Toshihiko Iizasa, Etsuko Toda, Koji Ohnishi, Francis H. W. Shand, Shiro Kanegasaki, Hiroki Nagase, Meiji Itakura, Hirofumi Nakano, Mitsuhiro Takeda, Sosuke Yoshinaga, Miki Ohira, Ming-Rong Zhang, Kazuhiro Okumura, Yuya Terashima, Hirotatsu Kojima, Kana Kokubo, Ming Chen Chen, Mikiya Otsuji, Yoshihiro Komohara, Yutaka Kofuku, Hirofumi Rokutan, Hiroaki Terasawa, Kouji Matsushima, Akira Shimizu
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Tumor-associated macrophages affect tumor progression and resistance to immune checkpoint therapy. Here, we identify the chemokine signal regulator FROUNT as a target to control tumor-associated macrophages. The low level FROUNT expression in patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be5ea522550499798f4ebb8e0eda0242
https://doi.org/10.1038/s41467-020-14338-5
https://doi.org/10.1038/s41467-020-14338-5
Autor:
Toshihiko Iizasa, Meiji Itakura, Ikuo Sekine, Yasushi Yoshida, Masato Shingyoji, Yoshihiko Sakashita, Hironori Ashinuma
Publikováno v:
International Journal of Clinical Oncology. 22:455-460
It is not uncommon for patients with lung cancer to receive supportive care alone. However, the clinical characteristics of these patients have not been fully studied. We conducted a retrospective study to identify the clinical characteristics of def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c8beb718692ee0de1ef605af2252ad2
https://doi.org/10.1007/s10147-017-1094-1
https://doi.org/10.1007/s10147-017-1094-1
Autor:
Takayoshi Okabe, Ichio Shimada, Koji Ohnishi, Francis H. W. Shand, Etsuko Toda, Hiroki Nagase, Toshihiko Iizasa, Hirofumi Nakano, Hiroaki Terasawa, Kouji Matsushima, Yoshihiro Komohara, Hirotatsu Kojima, Meiji Itakura, Yutaka Kofuku, Sana Yokoi, Kazuhiro Okumura, Ming-Rong Zhang, Hirofumi Rokutan, Mikiya Otsuji, Shiro Kanegasaki, Yuya Terashima, Miki Ohira, Sosuke Yoshinaga
Publikováno v:
SSRN Electronic Journal.
Tumor-associated macrophages influence tumor progression and resistance to immune checkpoint therapy. Chemokine signaling is a key regulator of macrophage accumulation and activity. Here, we report that the chemokine receptor-binding protein FROUNT m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffbf6bac390edf006cf70b5b5170b6a7
https://doi.org/10.2139/ssrn.3155880
https://doi.org/10.2139/ssrn.3155880
Autor:
Takahiro Nakajima, Masato Shingyoji, Mitsuru Yoshino, Koichiro Tatsumi, Toshihiko Iizasa, Meiji Itakura, Hironori Ashinuma, Yasushi Yoshida
Publikováno v:
The Annals of Thoracic Surgery. 98:1762-1767
Background Integrated positron emission tomography (PET) with computed tomography (CT) is a useful modality to investigate lymph node metastases for non-small cell lung cancer, but is less sensitive for normal-sized lymph nodes. We sometimes encounte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71efe7baaf94efc3da9476f100e14ae3
https://doi.org/10.1016/j.athoracsur.2014.05.078
https://doi.org/10.1016/j.athoracsur.2014.05.078
Autor:
Yuzo Hasegawa, Hironori Ashinuma, K. Kawasaki, Yasumitsu Moriya, T. Sakaida, Toshihiko Iuchi, Toshihiko Iizasa, Meiji Itakura, Hajime Tamura, Masato Shingyoji, Sana Yokoi, Yasushi Yoshida
Publikováno v:
International Journal of Clinical Oncology. 20:674-679
The brain is a frequent site of metastases from non-small-cell lung cancer (NSCLC). We analyzed the frequency of brain metastases (BMs) from NSCLC in the era of magnetic resonance images, and evaluated the correlation between epidermal growth factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04862e40b106c2f21b74e5af353a80c8
https://doi.org/10.1007/s10147-014-0760-9
https://doi.org/10.1007/s10147-014-0760-9
Autor:
Yuzo Hasegawa, T. Sakaida, Toshihiko Iizasa, O. Nagano, Sana Yokoi, Hajime Kageyama, K. Kawasaki, Masato Shingyoji, Kazuo Hatano, Meiji Itakura, Toshihiko Iuchi
Publikováno v:
Lung Cancer. 82:282-287
Background Brain metastases (BM) are a common in patients with lung cancer. Although whole-brain radiation therapy (WBRT) is the standard therapy, it may have a risk of decline in cognitive function of patients. In this study, we evaluated the effica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1881211aac61e4a1f4a32e7d576c5da9
https://doi.org/10.1016/j.lungcan.2013.08.016
https://doi.org/10.1016/j.lungcan.2013.08.016
Autor:
Hiroyuki Mano, Hideki Kimura, Kengo Takeuchi, Sana Yokoi, Takahiro Nakajima, Manabu Soda, Akira Nakagawara, Meiji Itakura, Hajime Kageyama, Yukiko Matsui, Toshihiko Iizasa, Miki Ohira, Masato Shingyoji, Makiko Itami, Mitsuru Yoshino, Dai Ikebe
Publikováno v:
Lung Cancer. 75:66-72
Background Anaplastic lymphoma kinase (ALK) fusion gene-positive lung cancer accounts for 4–5% of non-small cell lung carcinoma. A clinical trial of the specific inhibitor of ALK fusion-type tyrosine kinase is currently under way. Methods ALK fusio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ca5adae25e61ec3f254a96c4b83321
https://doi.org/10.1016/j.lungcan.2011.05.027
https://doi.org/10.1016/j.lungcan.2011.05.027
Autor:
Meiji Itakura, Takahiro Nakajima, Kazuhiro Yasufuku, Tetsushi Hirata, Masato Shingyoji, Makiko Itami, Hideki Kimura, Toshihiko Iizasa, Ryo Takahashi, Yukiko Matsui
Publikováno v:
Respirology. 16:90-94
Background and objective: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has typically been performed using the 22gauge (G) dedicated TBNA needle. Recently a new 21G TBNA needle has been introduced. The efficacy of using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba6d7b4b1e7fd11c9e824137e6e26096
https://doi.org/10.1111/j.1440-1843.2010.01871.x
https://doi.org/10.1111/j.1440-1843.2010.01871.x
Autor:
Meiji Itakura, Toshihiko Iizasa, Masato Singyoji, Koichiro Tatsumi, Hironori Ashinuma, Yasushi Yoshida
Publikováno v:
Internal medicine (Tokyo, Japan). 54(21)
We herein report two cases of thymomas diagnosed by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). In both cases, the tumor was adjacent to the central airway. Therefore, we attempted to perform EBUS-TBNA in order to ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508661aff55735a83d169654492bd274
https://pubmed.ncbi.nlm.nih.gov/26521902
https://pubmed.ncbi.nlm.nih.gov/26521902