The human equilibrative nucleoside transporter I mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia

Autor: Hubeek, I., Stam, R. W., Peters, G. J., Broekhuizen, R., Meijerink, J. P.P., Van Wering, E. R., Gibson, B. E.S., Creutzig, U., Zwaan, C. M., Cloos, J., Kuik, D. J., Pieters, R., Kaspers, G. J.L.

Publikováno v: Hubeek, I, Stam, R W, Peters, G J, Broekhuizen, R, Meijerink, J P P, Van Wering, E R, Gibson, B E S, Creutzig, U, Zwaan, C M, Cloos, J, Kuik, D J, Pieters, R & Kaspers, G J L 2005, ' The human equilibrative nucleoside transporter I mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia ', British Journal of Cancer, vol. 93, no. 12, pp. 1388-1394 . https://doi.org/10.1038/sj.bjc.6602881
British Journal of Cancer, 93(12), 1388-1394. Nature Publishing Group

Cytarabine (ara-C) is the most effective agent for the treatment of acute myeloid leukaemia (AML). Aberrant expression of enzymes involved in the transport/metabolism of ara-C could explain drug resistance. We determined mRNA expression of these fact

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