Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Meiheng Sun"'
Autor:
Tao Xiaohui, Luyao Wang, Xin Yang, Hewen Jiang, Ning Zhang, Huarui Zhang, Dijie Li, Xiaofei Li, Yihao Zhang, Shenghang Wang, Chuanxin Zhong, Sifan Yu, Meishen Ren, Meiheng Sun, Nanxi Li, Tienan Chen, Yuan Ma, Fangfei Li, Jin Liu, Yuanyuan Yu, Hua Yue, Zhenlin Zhang, Ge Zhang
Publikováno v:
Journal of Orthopaedic Translation, Vol 47, Iss , Pp 39-49 (2024)
Sclerostin emerges as a novel target for bone anabolic therapy in bone diseases. Osteogenesis imperfecta (OI) and X-linked hypophosphatemia (XLH) are rare bone diseases in which therapeutic potential of sclerostin inhibition cannot be ignored. In OI,
Externí odkaz:
https://doaj.org/article/af3deae3ca544e9785bfc76fae85e201
Autor:
Yuanyuan Yu, Luyao Wang, Shuaijian Ni, Dijie Li, Jin Liu, Hang Yin Chu, Ning Zhang, Meiheng Sun, Nanxi Li, Qing Ren, Zhenjian Zhuo, Chuanxin Zhong, Duoli Xie, Yongshu Li, Zong-Kang Zhang, Huarui Zhang, Mei Li, Zhenlin Zhang, Lin Chen, Xiaohua Pan, Weibo Xia, Shu Zhang, Aiping Lu, Bao-Ting Zhang, Ge Zhang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Antibodies targeting sclerostin can ameliorate postmenopausal osteoporosis but present some cardiovascular risk. Here the authors show that the cardiovascular and skeletal effects of sclerostin are mediated by different loops, suggesting ways to pres
Externí odkaz:
https://doaj.org/article/ff38f6e32b034261a6747ac670344b44
Autor:
Sifan Yu, Dijie Li, Ning Zhang, Shuaijian Ni, Meiheng Sun, Luyao Wang, Huan Xiao, Dingdong Liu, Jin Liu, Yuanyuan Yu, Zongkang Zhang, Samuel Tin Yui Yeung, Shu Zhang, Aiping Lu, Zhenlin Zhang, Baoting Zhang, Ge Zhang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 5, Pp 2150-2170 (2022)
Sclerostin, a protein secreted from osteocytes, negatively regulates the WNT signaling pathway by binding to the LRP5/6 co-receptors and further inhibits bone formation and promotes bone resorption. Sclerostin contributes to musculoskeletal system-re
Externí odkaz:
https://doaj.org/article/c0e2422c0f3d479ab42ed5320b3ed31a
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13539 (2023)
The members of the cytokine interleukin 17 (IL-17) family, along with their receptors (IL-17R), are vital players in a range of inflammatory diseases and cancer. Although generally regarded as proinflammatory, the effects they exhibit on cancer progr
Externí odkaz:
https://doaj.org/article/bbaab48f905b49f781ae21bca4a51805
The Roles of Sclerostin in Immune System and the Applications of Aptamers in Immune-Related Research
Autor:
Meiheng Sun, Zihao Chen, Xiaoqiu Wu, Yuanyuan Yu, Luyao Wang, Aiping Lu, Ge Zhang, Fangfei Li
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Wnt signaling is one of the fundamental pathways that play a major role in almost every aspect of biological systems. In addition to the well-known influence of Wnt signaling on bone formation, its essential role in the immune system also attracted i
Externí odkaz:
https://doaj.org/article/5e414474b9b2457699b03075008d1490
Autor:
Meiheng Sun, Xiaoqiu Wu, Yuanyuan Yu, Luyao Wang, Duoli Xie, Zhenlin Zhang, Lin Chen, Aiping Lu, Ge Zhang, Fangfei Li
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Since calcium and phosphorus play vital roles in a multitude of physiologic systems, disorders of calcium and phosphorus metabolism always lead to severe consequences such as skeletal-related and cardiovascular morbidity, or even life-threatening. Ph
Externí odkaz:
https://doaj.org/article/36def5e7ffef4af0a6c9402dbf8ff4fb
Autor:
Qing Chen1, Meiheng Sun1, Xu Han1, Hongfei Xu1 hongfei.xu@ucsf.edu, Yongjian Liu1,2 yjliu@pitt.edu
Publikováno v:
Journal of Biomedical Research. Nov2023, Vol. 37 Issue 6, p492-506. 15p.
Autor:
Luyao Wang, Yuanyuan Yu, Shuaijian Ni, Dijie Li, Jin Liu, Duoli Xie, Hang Yin Chu, Qing Ren, Chuanxin Zhong, Ning Zhang, Nanxi Li, Meiheng Sun, Zong-Kang Zhang, Zhenjian Zhuo, Huarui Zhang, Shu Zhang, Mei Li, Weibo Xia, Zhenlin Zhang, Lin Chen, Peng Shang, Xiaohua Pan, Aiping Lu, Bao-Ting Zhang, Ge Zhang
Publikováno v:
Theranostics. 12:5645-5674
Autor:
Luyao Wang, Ning Zhang, Jin Liu, Xin Yang, Yuanyuan Yu, Dijie Li, Hewen Jiang, Meiheng Sun, Nanxi LI, Daqing Ma, Yu Huang, Aiping Lu, Baoting Zhang, Ge Zhang
Publikováno v:
Metabolism. 142:155427