Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Meifeng Tao"'
Autor:
Penghui Dai, Yuyao Qin, Luyuan Li, Haidi Li, Lihuo Lv, Danying Xu, Yuqing Song, Tingting Huang, Shuangjun Lin, Zixin Deng, Meifeng Tao
Publikováno v:
Synthetic and Systems Biotechnology, Vol 8, Iss 3, Pp 486-497 (2023)
Tylosin is a 16-membered macrolide antibiotic widely used in veterinary medicine to control infections caused by Gram-positive pathogens and mycoplasmas. To improve the fermentation titer of tylosin in the hyperproducing Streptomyces xinghaiensis str
Externí odkaz:
https://doaj.org/article/68d358aafc374df6b09aae27d4af8924
Autor:
Yong Sheng, Hengyu Wang, Yixin Ou, Yingying Wu, Wei Ding, Meifeng Tao, Shuangjun Lin, Zixin Deng, Linquan Bai, Qianjin Kang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract CRISPR-Cas immunity systems safeguard prokaryotic genomes by inhibiting the invasion of mobile genetic elements. Here, we screened prokaryotic genomic sequences and identified multiple natural transpositions of insertion sequences (ISs) into
Externí odkaz:
https://doaj.org/article/3ba99588949d43d9b6f109ea27b45e01
Publikováno v:
Marine Drugs, Vol 22, Iss 4, p 189 (2024)
Polyene macrolactams are a special group of natural products with great diversity, unique structural features, and a wide range of biological activities. Herein, a cryptic gene cluster for the biosynthesis of putative macrolactams was disclosed from
Externí odkaz:
https://doaj.org/article/13e5ead930c94bd083168b224d5e7412
Autor:
Jin Lü, Qingshan Long, Zhilong Zhao, Lu Chen, Weijun He, Jiali Hong, Kai Liu, Yemin Wang, Xiuhua Pang, Zixin Deng, Meifeng Tao
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Bacteria of the genus Saccharopolyspora produce important polyketide antibiotics, including erythromycin A (Sac. erythraea) and spinosad (Sac. spinosa). We herein report the development of an industrial erythromycin-producing strain, Sac. erythraea H
Externí odkaz:
https://doaj.org/article/62326e3587994f01be17ae109d7ef475
Autor:
Qinying Peng, Guixi Gao, Jin Lü, Qingshan Long, Xuefei Chen, Fei Zhang, Min Xu, Kai Liu, Yemin Wang, Zixin Deng, Zhiyong Li, Meifeng Tao
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Streptomyces lividans is a suitable host for the heterologous expression of biosynthetic gene clusters (BGCs) from actinomycetes to discover “cryptic” secondary metabolites. To improve the heterologous expression of BGCs, herein we optimized S. l
Externí odkaz:
https://doaj.org/article/2955ad01e267477e808676c5e27246a9
Autor:
Peipei Zhang, Lili Wu, Yanping Zhu, Meng Liu, Yemin Wang, Guangxiang Cao, Xiu-Lan Chen, Meifeng Tao, Xiuhua Pang
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
The developmental life cycle of Streptomyces species includes aerial hyphae formation and spore maturation, two distinct developmental processes that are controlled, respectively, by two families of developmental regulatory genes, bld and whi. In thi
Externí odkaz:
https://doaj.org/article/7b398355b58a4e00ae7af950c5c43cf4
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 6, Pp 10855-10867 (2014)
To improve the efficacy and safety of dural repair in neurosurgical procedures, a new dural material derived from bacterial cellulose (BC) was evaluated in a rabbit model with dural defects. We prepared artificial dura mater using bacterial cellulose
Externí odkaz:
https://doaj.org/article/2e1ef6de6286491aa466ea61802d3e2e
Publikováno v:
Environmental Microbiology. 24:3081-3096
Our previous study using transposon mutagenesis indicated that disruption of the putative response regulator gene orrA impacted antibiotic production in Streptomyces coelicolor. In this study, the role of OrrA was further characterized by comparing t
Autor:
Meifeng Tao, Yixin Ou, Qianjin Kang, Linquan Bai, Hengyu Wang, Xiaojing Hu, Zixin Deng, Yong Sheng, Xing Li
Publikováno v:
ACS Synthetic Biology. 10:2210-2221
Great efforts have been made to improve Streptomyces chassis for efficient production of targeted natural products. Moenomycin family antibiotics, represented by moenomycin (Moe) and nosokomycin, are phosphoglycolipid antibiotics that display extraor
Autor:
Yanping Zhu, Yinhua Lu, Peipei Zhang, Aiying Li, Meifeng Tao, Xiuhua Pang, Ting Lu, Xinyuan Wang
Publikováno v:
Environmental Microbiology. 23:6907-6923
Phosphate metabolism is known to be regulated by the PhoPR regulatory system in Streptomyces and some other bacteria. In this study, we report that MtrA also regulates phosphate metabolism in Streptomyces. Our data showed that, in Streptomyces coelic