Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Mei-Yao Lin"'
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Little is known about the pathways that maintain mitochondrial structure and function under neuronal stress conditions. Here, authors demonstrate that the Mul1-Mfn2 pathway plays a checkpoint role in maintaining mitochondrial integrity and energy mai
Externí odkaz:
https://doaj.org/article/6f1424b4200a43308728c4d36f509016
Autor:
Kuei-Min Chung, Shu-Ching Hsu, Yue-Ru Chu, Mei-Yao Lin, Weir-Tong Jiaang, Ruey-Hwa Chen, Xin Chen
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88772 (2014)
BACKGROUND: The ability of human bone marrow mesenchymal stem cells (BM-MSCs) to migrate and localize specifically to injured tissues is central in developing therapeutic strategies for tissue repair and regeneration. Fibroblast activation protein (F
Externí odkaz:
https://doaj.org/article/0dea8211f5234ba4babed624c9e07f72
Autor:
Mei-Yao Lin, 林美瑤
104
Modern discovery of anti-cancer therapeutics emphasizes the significance of molecular targets, i.e. oncoproteins, in the early process, since these targets should be used as the structural and functional basis for screening of chemicals or b
Modern discovery of anti-cancer therapeutics emphasizes the significance of molecular targets, i.e. oncoproteins, in the early process, since these targets should be used as the structural and functional basis for screening of chemicals or b
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/69096877629364013041
Autor:
Mei-Yao Lin, 林美瑤
99
The induction of neurite outgrowth and arborization is critical for developmental and regenerative processes. Here we report that the BTB-kelch protein KLHL20 promoted neurite outgrowth and arborization in hippocampal and cortical neurons thr
The induction of neurite outgrowth and arborization is critical for developmental and regenerative processes. Here we report that the BTB-kelch protein KLHL20 promoted neurite outgrowth and arborization in hippocampal and cortical neurons thr
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/40561246296220242260
Autor:
Mei-Yao Lin, 林美瑤
93
The accumulated evidences show that the dynamic behaviors (fission and fusion) of mitochondria are crucial for many cellular functions. Mitochondrial fusion serves to mix and to unify the mitochondrial compartment, which are important in cell
The accumulated evidences show that the dynamic behaviors (fission and fusion) of mitochondria are crucial for many cellular functions. Mitochondrial fusion serves to mix and to unify the mitochondrial compartment, which are important in cell
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/54626194590054301664
Autor:
Xiu-Tang Cheng, Zu-Hang Sheng, Tamar Farfel-Becker, Frances M. Platt, Ning Huang, Mei-Yao Lin, Yuxiang Xie, Sunan Li, Joseph C. Roney, Tao Sun
Publikováno v:
Autophagy. 17:1796-1798
Efficient degradation of autophagic vacuoles (AVs) generated at axon terminals by mature lysosomes enriched in the cell body represents an exceptional challenge that neurons face in maintaining cellular homeostasis. Here, we discuss our recent findin
Autor:
Zu-Hang Sheng, Ning Huang, Tao Sun, Gui-Jing Xiong, Yuxiang Xie, Mei-Yao Lin, Xiu-Tang Cheng, Sunan Li
Publikováno v:
Molecular psychiatry
The formation and maintenance of synapses require long-distance delivery of newly synthesized synaptic proteins from the soma to distal synapses, raising the fundamental question of whether impaired transport is associated with neurodevelopmental dis
Publikováno v:
Autophagy
Chronic mitochondrial stress is associated with major neurodegenerative diseases; and thus, the recovery of those mitochondria constitutes a critical step of energy maintenance in early stages of neurodegeneration. Our recent study provides the first
Autor:
Frances M. Platt, Xiu-Tang Cheng, Sunan Li, Zu-Hang Sheng, Joseph C. Roney, Tao Sun, Tamar Farfel-Becker, Mei-Yao Lin, Ning Huang, Yuxiang Xie
Publikováno v:
Autophagy
Dev Cell
Dev Cell
Efficient degradation of autophagic vacuoles (AVs) generated at axon terminals by mature lysosomes enriched in the cell body represents an exceptional challenge that neurons face in maintaining cellular homeostasis. Here, we discuss our recent findin
Autor:
Hsuan An Chen, Ruey-Hwa Chen, Si Tse Jiang, Chun Ming Chen, Yu Ching Lin, Pei Rung Wu, Yu-Hsuan Chen, Liang Yu Pang, Ting Fen Tsai, Chin Chih Liu, Mei-Yao Lin
Publikováno v:
Molecular Cell. 61:84-97
Summary Autophagy, a cellular self-eating mechanism, is important for maintaining cell survival and tissue homeostasis in various stressed conditions. Although the molecular mechanism of autophagy induction has been well studied, how cells terminate