Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Mei-Shu Shih"'
Autor:
Mei-Shu Shih
Publikováno v:
Journal of Orthopaedic Translation, Vol 3, Iss 2, Pp 85-88 (2015)
Transitional medicine/science is shifting the medical research paradigm from compound-based to evidence-based drug/device discovery. It is increasing interdisciplinary collaborations, enhancing usage of advanced technologies, and facilitating therape
Externí odkaz:
https://doaj.org/article/fc17856a6aea43c4be1908ad47e67c9b
Autor:
Mei-Shu Shih, Julie O'Connell, Andrew L. Raines, Chen-Wei Su, Scheffer C.G. Tseng, Lorraine Chua
Publikováno v:
Tissue Engineering Part A. 23:12-19
Osteoarthritis (OA) is a progressive degenerative joint disease, and to date, no disease-modifying OA drug exists. Amniotic membrane and umbilical cord products have been used clinically in several diseases due to their anti-inflammatory and antiscar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e334675e032a244e44b00b890e3112d2
https://doi.org/10.1089/ten.tea.2016.0088
https://doi.org/10.1089/ten.tea.2016.0088
Autor:
Mei-Shu Shih, Mary Belfast, Brenda L Pennypacker, Helen Zheng, Le T. Duong, Rana Samadfam, Charles Chen
Publikováno v:
Journal of Bone and Mineral Research. 29:1847-1858
Treatment with the cathepsin K (CatK) inhibitor odanacatib (ODN) protects against bone loss and maintains normal biomechanical properties in the spine and hip of ovariectomized (OVX) preclinical models. Here, we characterized the effects of ODN on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74b1d8504bce165ac7abddd129147af3
https://doi.org/10.1002/jbmr.2211
https://doi.org/10.1002/jbmr.2211
Autor:
Bei Tao, Hong-yan Zhao, Dong-mei Liu, Pei-lin Jiao, Lin Zhao, Dian-dian Zhao, Ting-ting Liu, Li-hao Sun, Jian-min Liu, Mei-Shu Shih
Publikováno v:
Bone. 90
Mammalian target of rapamycin (mTOR) is a Ser/Thr kinase conserved through evolution that coordinates extra cellular signals associated with cell growth. Main functions of mTOR present in the form of two complexes, namely mTORC1 and mTORC2, which are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b109e6005710a049cff77eeb2d5ec6
https://pubmed.ncbi.nlm.nih.gov/27262777
https://pubmed.ncbi.nlm.nih.gov/27262777
Publikováno v:
Journal of Bone and Mineral Research. 5:1257-1263
We describe a young woman who acquired a painful, diffuse osteosclerosis of the cervical, thoracic, and lumbar spine, pelvis, and long bones of the legs as an adult. Bone densitometry showed a large increase in apparent bone density. Skeletal radiogr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2de20d46dfb726f243091d2191a5892
https://doi.org/10.1002/jbmr.5650051211
https://doi.org/10.1002/jbmr.5650051211
Autor:
Jerome Connor, Qing-Qing Qiu, Patricia A. Murphy, Sana C. Roesch, Kimberly Stock, Teri Panzitta, Mei-Shu Shih
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. :239-245
Demineralized bone matrix (DBM) has been investigated as a bone graft substitute for spinal fusion with less morbidity. Various carriers have been added to DBM to enhance its handling characteristics. This study investigates the spinal fusion induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db7261e1256eba33f0d677cd93b8b9d9
https://doi.org/10.1002/jbm.b.30726
https://doi.org/10.1002/jbm.b.30726
Autor:
Steven A. Martinez, James D. Lincoln, Joanne Hughes, Mei-Shu Shih, Michael A Nawrocki, Hellen Zheng, William J Carroll
Publikováno v:
Veterinary and Comparative Orthopaedics and Traumatology. 19:72-80
SummarySpinal fusion surgery for alleviation of intractable lower back pain in humans is currently a primary therapeutic technique, with failure rates averaging between 5 to 35%. Implanted and external source-based electrical stimulation devices have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c39ddf55ae05085cc3aac8a1c718dafc
https://doi.org/10.1055/s-0038-1632978
https://doi.org/10.1055/s-0038-1632978
Autor:
Mei-Shu Shih
Publikováno v:
Current Osteoporosis Reports. 10:187-189
Osteoporosis is a clinical manifestation of fracture from weakened bone tissues. Fracture is the result of incompatibility between biomechanical loading forces and material properties of bone tissues. Bone tissues constantly renew themselves and reno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128f260c0957b562dd0f07dc522da0eb
https://doi.org/10.1007/s11914-012-0107-2
https://doi.org/10.1007/s11914-012-0107-2
Autor:
Mei-Shu Shih
Publikováno v:
Journal of Orthopaedic Translation
Journal of Orthopaedic Translation, Vol 3, Iss 2, Pp 85-88 (2015)
Journal of Orthopaedic Translation, Vol 3, Iss 2, Pp 85-88 (2015)
Summary Transitional medicine/science is shifting the medical research paradigm from compound-based to evidence-based drug/device discovery. It is increasing interdisciplinary collaborations, enhancing usage of advanced technologies, and facilitating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::457338af32d2353ccc8f6db0dfd61a3c
https://pubmed.ncbi.nlm.nih.gov/30035044
https://pubmed.ncbi.nlm.nih.gov/30035044
Autor:
Mislav Jelić, Don Jin, Vanja Bašić, Nikolina Bašić, Susan Ryan, Haimanti Dorai, J. Maliakal, B. Dattatreyamurty, Ana Stavljenić, Alyssa A. Shepard, Dunja Rogić, Denise Griffiths, T. K. Sampath, Mei-Shu Shih, Slobodan Vukicevic, W. Jones, M. Pastorcic
Publikováno v:
Journal of Clinical Investigation. 102:202-214
We have shown that osteogenic protein-1 (OP-1) (bone morphogenetic protein-7) is responsible for the induction of nephrogenic mesenchyme during embryonic kidney development. Gene knock-out studies showed that OP-1 null mutant mice die of renal failur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9fbf7880c1ef8462db0cff75f7fc442
https://doi.org/10.1172/jci2237
https://doi.org/10.1172/jci2237