Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mei-Qin Xue"'
Autor:
Siqi Wu, En-Duo Wang, Xiao-Long Zhou, Mei-Qin Xue, Jing-Bo Zhou, Pengfei Fang, Yong Wang, Qi-Yu Zeng
Publikováno v:
Science China Life Sciences. 63:1227-1239
Aminoacyl-tRNA synthetases (aaRSs) are ubiquitously expressed, essential enzymes, synthesizing aminoacyl-tRNAs for protein synthesis. Functional defects of aaRSs frequently cause various human disorders. Human KARS encodes both cytosolic and mitochon
Autor:
Mei-Qin Xue, Jing-Bo Zhou, En-Duo Wang, Xiao-Long Zhou, Gui-Xin Peng, Wen-Qiang Zheng, Qi-Yu Zeng, Guang Li
Publikováno v:
Nucleic Acids Research
Alanyl-tRNA synthetases (AlaRSs) from three domains of life predominantly rely on a single wobble base pair, G3-U70, of tRNAAla as a major determinant. However, this base pair is divergent in human mitochondrial tRNAAla, but instead with a translocat
Publikováno v:
Nucleic Acids Research
TARS and TARS2 encode cytoplasmic and mitochondrial threonyl-tRNA synthetases (ThrRSs) in mammals, respectively. Interestingly, in higher eukaryotes, a third gene, TARSL2, encodes a ThrRS-like protein (ThrRS-L), which is highly homologous to cytoplas
Autor:
En-Duo Wang, Ru-Juan Liu, Yun Chen, Zhi-Rong Ruan, Mei-Qin Xue, Zhi-Peng Fang, Xiao-Long Zhou, Yong Wang
Publikováno v:
Journal of Biological Chemistry. 291:21208-21221
Translational fidelity mediated by aminoacyl-tRNA synthetases ensures the generation of the correct aminoacyl-tRNAs, which is critical for most species. Threonyl-tRNA synthetase (ThrRS) contains multiple domains, including an N2 editing domain. Of th
Publikováno v:
Fitoterapia. 83:1281-1285
An aqueous ethanol extract of Artemisia argyi inhibited the aminoacylation activity of LeuRS from Giardia lamblia (GlLeuRS). The bioassay-guided fractionation of the extract led to the isolation of 3,5-dicaffeoylquinic acid (1), with an IC₅₀ of 5
Publikováno v:
The Journal of biological chemistry. 283(33)
Leucyl-tRNA synthetase (LeuRS) contains an editing domain that discriminates leucine from noncognate amino acids to ensure translational fidelity. In this study, a knock-out strain for Saccharomyces cerevisiae LeuRS was constructed to analyze in vivo
Autor:
Xiao-Long Zhou1, Yun Chen1, Zhi-Peng Fang1, Zhi-Rong Ruan1, Yong Wang2, Ru-Juan Liu1, Mei-Qin Xue1, En-Duo Wang1,2 edwang@sibcb.ac.cn
Publikováno v:
Journal of Biological Chemistry. 9/30/2016, Vol. 291 Issue 40, p21208-21221. 14p.
Autor:
Peng Yao1, Xiao-Long Zhou1, Ran He1, Mei-Qin Xue1, Yong-Gang Zheng1, Yue-Fei Wang1, En-Duo Wang1 edwang@sibs.ac.cn
Publikováno v:
Journal of Biological Chemistry. 8/15/2008, Vol. 283 Issue 33, p22591-22600. 10p. 1 Diagram, 1 Chart, 5 Graphs.