Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Mei-I Chung"'
Autor:
Linh T. Bui, Nichelle I. Winters, Mei-I Chung, Chitra Joseph, Austin J. Gutierrez, Arun C. Habermann, Taylor S. Adams, Jonas C. Schupp, Sergio Poli, Lance M. Peter, Chase J. Taylor, Jessica B. Blackburn, Bradley W. Richmond, Andrew G. Nicholson, Doris Rassl, William A. Wallace, Ivan O. Rosas, R. Gisli Jenkins, Naftali Kaminski, Jonathan A. Kropski, Nicholas E. Banovich, Human Cell Atlas Lung Biological Network
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Patients with chronic lung disease (CLD) have an increased risk for severe coronavirus disease-19 and poor outcomes. Here the authors compare the transcriptomes of single cells isolated from healthy and CLD lungs to identify molecular characteristics
Externí odkaz:
https://doaj.org/article/8c96b7d10ceb4972b8de290313cf45fb
Autor:
Taejoon Kwon, Mei-I Chung, Rakhi Gupta, Julie C. Baker, John B. Wallingford, Edward M. Marcotte
Publikováno v:
Genomics Data, Vol 2, Iss C, Pp 192-194 (2014)
Recently, using the frog Xenopus laevis as a model system, we showed that the transcription factor Rfx2 coordinates many genes involved in ciliogenesis and cell movement in multiciliated cells (Chung et al., 2014). To our knowledge, it was the first
Externí odkaz:
https://doaj.org/article/c53eee1d7f934b31ab864d472c7ae07e
Autor:
Mei-I Chung, Taejoon Kwon, Fan Tu, Eric R Brooks, Rakhi Gupta, Matthew Meyer, Julie C Baker, Edward M Marcotte, John B Wallingford
Publikováno v:
eLife, Vol 3 (2014)
The mechanisms linking systems-level programs of gene expression to discrete cell biological processes in vivo remain poorly understood. In this study, we have defined such a program for multi-ciliated epithelial cells (MCCs), a cell type critical fo
Externí odkaz:
https://doaj.org/article/c3a6cc19af7c42d98759270e42cfea86
Autor:
Mei-I Chung, 鍾美儀
93
Epigenetics is the study of heritable changes in gene expression that are not mediated at the DNA sequence level. The human and mouse HIC1 (hypermethylated in cancer-1) genes are composed of two alternative transcripts, both of which have a l
Epigenetics is the study of heritable changes in gene expression that are not mediated at the DNA sequence level. The human and mouse HIC1 (hypermethylated in cancer-1) genes are composed of two alternative transcripts, both of which have a l
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/61634782498677949503
Autor:
Heini M Natri, Christina B Del Azodi, Lance Peter, Chase J Taylor, Sagrika Chugh, Robert Kendle, Mei-i Chung, David K Flaherty, Brittany K Matlock, Carla L Calvi, Timothy S Blackwell, Lorraine B Ware, Matthew Bacchetta, Rajat Walia, Ciara M Shaver, Jonathan A Kropski, Davis J McCarthy, Nicholas E Banovich
Publikováno v:
bioRxiv
Common genetic variants confer substantial risk for chronic lung diseases, including pulmonary fibrosis (PF). Defining the genetic control of gene expression in a cell-type-specific and context-dependent manner is critical for understanding the mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb33f8d2914884f147f02fc19d6ac0f
https://europepmc.org/articles/PMC10055257/
https://europepmc.org/articles/PMC10055257/
Autor:
Malte Luecken, Lisa Sikkema, Daniel Strobl, Luke Zappia, Elo Madissoon, Nikolay Markov, Laure-Emmanuelle Zaragosi, Meshal Ansari, Marie-Jeanne Arguel, Leonie Apperloo, Christophe Becavin, Marijn Berg, Evgeny Chichelnitskiy, Mei-i Chung, Antoine Collin, Aurore Gay, Baharak Hooshiar Kashani, Manu Jain, Theodore Kapellos, Tessa Kole, Christoph Mayr, Michael von Papen, Lance Peter, Ciro Ramírez-Suástegui, Janine Schniering, Chase Taylor, Thomas Walzthoeni, Chuan Xu, Linh Bui, Carlo de Donno, Leander Dony, Minzhe Guo, Austin Gutierrez, Lukas Heumos, Ni Huang, Ignacio Ibarra Del Río, Nathan Jackson, Preetish Kadur Lakshminarasimha Murthy, Mohammad Lotfollahi, Tracy Tabib, Carlos Talavera-Lopez, Kyle Travaglini, Anna Wilbrey-Clark, Kaylee Worlock, Masahiro Yoshida, Tushar Desai, Orit Rozenblatt-Rosen, Christine Falk, Naftali Kaminski, Mark Krasnow, Robert Lafyatis, Marko Nikolic, Joseph Powell, Jay Rajagopal, Max Seibold, Dean Sheppard, Douglas Shepherd, Sarah Teichmann, Alexander Tsankov, Jeffrey Whitsett, Yan Xu, Nicholas Banovich, Pascal Barbry, Thu Duong, Kerstin Meyer, Jonathan Kropski, Dana Pe'er, Herbert Schiller, Purushothama Rao Tata, Joachim Schultze, Maarten van den Berge, Yuexin Chen, James Hagood, Ahmed Hassan, Peter Horvath, Joakim Lundeberg, Sylvie Leroy, Charles Marquette, Gloria Pryhuber, Christos Samakovlis, Xin Sun, Lorraine Ware, Kun Zhang, Alexander Misharin, Martijn Nawijn, Fabian Theis
Organ- and body-scale cell atlases have the potential to transform our understanding of human biology. To capture the variability present in the population, these atlases must include diverse demographics such as age and ethnicity from both healthy a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c225b8ec842494e3c796c31c793715c
https://doi.org/10.21203/rs.3.rs-1438584/v1
https://doi.org/10.21203/rs.3.rs-1438584/v1
Autor:
Nichelle I. Winters, Taylor Adams, Jessica B. Blackburn, Mei-I Chung, Andrew G. Nicholson, William A Wallace, Bradley W. Richmond, Naftali Kaminski, Jonas C. Schupp, Sergio Poli, Linh T. Bui, Austin J. Gutierrez, Lance M. Peter, Chase J. Taylor, Chitra Joseph, Ivan O. Rosas, Jonathan A. Kropski, R. Gisli Jenkins, Arun C. Habermann, Doris Rassl, Nicholas E. Banovich
Publikováno v:
Nature Communications, 12(1):4314. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Patients with chronic lung disease (CLD) have an increased risk for severe coronavirus disease-19 (COVID-19) and poor outcomes. Here, we analyze the transcriptomes of 611,398 single cells isolated from healthy and CLD lungs to identify molecular char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93c3c96e7485734a7e7e44b05fc005a3
https://research.rug.nl/en/publications/ad01d54a-3745-4a72-9ee7-b5193dd49e2c
https://research.rug.nl/en/publications/ad01d54a-3745-4a72-9ee7-b5193dd49e2c
Autor:
Linh T. Bui, Heini M. Natri, Lance M. Peter, Bianca Argente, Austin J. Gutierrez, Arnold Federico, Mei-I Chung, Jonathan Keats, Nicholas E. Banovich
Publikováno v:
Cancer Research. 82:5780-5780
Multiple myeloma (MM) is a malignancy of plasma cells in the bone marrow and the second most common hematological malignancy. MM is characterized by a high degree of heterogeneity and has a hereditary genetic component with relatives of MM patients h
Autor:
Christine E. Brown, Sophia Zhang, Renate Starr, Austin J. Gutierrez, Lance M. Peter, Nicholas E. Banovich, Darya Alizadeh, Stephanie L. Yahn, Mei-I Chung
Publikováno v:
Neuro Oncol
Recent advances in immunotherapy, particularly chimeric antigen receptor (CAR)-engineered T cell therapy, have shown promise for the treatment of many tumor types including progressive recurrent glioblastoma (GBM). While early phase clinical trials h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8346bcb2d33a2cd431a8afbf13822f79
https://europepmc.org/articles/PMC7651225/
https://europepmc.org/articles/PMC7651225/
Autor:
Nichelle I. Winters, Jennifer M.S. Sucre, Carla L. Calvi, Linh T. Bui, Ana P. Serezani, Ross M. Bremner, Simon B. Mallal, Rajat Walia, Matthew J. Bacchetta, Lorraine B. Ware, Chase J. Taylor, Jamie Roberson, Wyatt J. McDonnell, Ciara M. Shaver, Bradley W. Richmond, Austin J. Gutierrez, Lance M. Peter, James E. Loyd, Christopher S. Jetter, Timothy S. Blackwell, Jonathan A. Kropski, Nicholas E. Banovich, Stephanie L. Yahn, Latha Raju, Lori Wood, Guixiao Ding, Arun C. Habermann, Mei-I Chung
Publikováno v:
Science Advances
Single-cell RNA sequencing provides new insights into pathologic epithelial and mesenchymal remodeling in the human lung.
Pulmonary fibrosis (PF) is a form of chronic lung disease characterized by pathologic epithelial remodeling and accumulatio
Pulmonary fibrosis (PF) is a form of chronic lung disease characterized by pathologic epithelial remodeling and accumulatio