Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mei-Guang Xiong"'
Autor:
Yong Ran, Dan Li, Mei-Guang Xiong, Hua-Nan Liu, Tao Feng, Zheng-Wang Shi, Yu-Hui Li, Huang-Ning Wu, Su-Yun Wang, Hai-Xue Zheng, Yan-Yi Wang
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1010270 (2022)
ASFV is a large DNA virus that is highly pathogenic in domestic pigs. How this virus is sensed by the innate immune system as well as why it is so virulent remains enigmatic. In this study, we show that the ASFV genome contains AT-rich regions that a
Externí odkaz:
https://doaj.org/article/71cf65a7f51d4c229f77761f2a67e503
Autor:
Yu-Hui Li, Jiang-Ling Peng, Zhi-Sheng Xu, Mei-Guang Xiong, Huang-Ning Wu, Su-Yun Wang, Dan Li, Guo-Qiang Zhu, Yong Ran, Yan-Yi Wang
Publikováno v:
Journal of Virology. 97
ASF is an acute disease in domestic pigs caused by infection with ASFV. ASF has become a global threat with devastating economic and ecological consequences.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df722f3b7e4ceb2416d1fb07ffcda4ff
https://doi.org/10.1128/jvi.01942-22
https://doi.org/10.1128/jvi.01942-22
Autor:
Yong Ran, Dan Li, Mei-Guang Xiong, Hua-Nan Liu, Tao Feng, Zheng-Wang Shi, Yu-Hui Li, Huang-Ning Wu, Su-Yun Wang, Hai-Xue Zheng, Yan-Yi Wang
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1010270 (2022)
ASFV is a large DNA virus that is highly pathogenic in domestic pigs. How this virus is sensed by the innate immune system as well as why it is so virulent remains enigmatic. In this study, we show that the ASFV genome contains AT-rich regions that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de0b512cdb5490664b6935e61b81958
https://pubmed.ncbi.nlm.nih.gov/35089988
https://pubmed.ncbi.nlm.nih.gov/35089988
Publikováno v:
The Journal of Immunology. 203:1560-1570
STING plays central roles in the innate immune response to pathogens that contain DNA. Sensing cytoplasmic DNA by cyclic GMP-AMP synthase produces cyclic GMP-AMP, which binds to and activates STING and induces STING translocation from the endoplasmic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc90fba419b51ec2200ae549e665183
https://doi.org/10.4049/jimmunol.1900387
https://doi.org/10.4049/jimmunol.1900387
Autor:
Zhi-Sheng Xu, Su-Yun Wang, Mei-Guang Xiong, Wei-Wei Li, Yan Yang, Yong Ran, Ying Nie, Yan-Yi Wang, Wei-Wei Luo
Publikováno v:
Proc Natl Acad Sci U S A
Trafficking of toll-like receptor 3 (TLR3) from the endoplasmic reticulum (ER) to endolysosomes and its subsequent proteolytic cleavage are required for it to sense viral double-stranded RNA (dsRNA) and trigger antiviral response, yet the underlying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7efc23a592d96e1605489b485ee4fe
https://pubmed.ncbi.nlm.nih.gov/32878999
https://pubmed.ncbi.nlm.nih.gov/32878999
Publikováno v:
EMBO Rep
Toll-like receptors (TLRs) are important pattern recognition receptors (PRRs) that are critical for the defense against invading pathogens. IL-1β is an important pro-inflammatory cytokine that also plays pivotal roles in shaping the adaptive immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9141a7e9dc4291e6246695b54850d50a
https://doi.org/10.15252/embr.201948860
https://doi.org/10.15252/embr.201948860
Publikováno v:
The Journal of Immunology. 208:1310-1310
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c8428346e2478f413fa5e862828058
https://doi.org/10.4049/jimmunol.2101093
https://doi.org/10.4049/jimmunol.2101093
Publikováno v:
Virologica Sinica
The cGAS-MITA pathway of cytosolic DNA sensing plays essential roles in immune response against pathogens that contain DNA or with DNA production in their life cycles. The cGAS-MITA pathway also detects leaked or aberrant accumulated self DNA in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0829ff77a83521c86593782a628ff2c8
http://europepmc.org/articles/PMC5934468
http://europepmc.org/articles/PMC5934468
Autor:
Wei-Wei Li, Ying Nie, Yan Yang, Yong Ran, Wei-Wei Luo, Mei-Guang Xiong, Su-Yun Wang, Zhi-Sheng Xu, Yan-Yi Wang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 9/22/2020, Vol. 117 Issue 38, p23707-23716, 10p
Autor:
Yong Ran1 ranyong@wh.iov.cn, Mei-guang Xiong1, Zhi-sheng Xu1, Wei-wei Luo1, Su-yun Wang1, Yan-Yi Wang1
Publikováno v:
Journal of Immunology. 9/15/2019, Vol. 203 Issue 6, p1560-1570. 11p.