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A rapid, semi-quantitative assay to screen for modulators of alpha-synuclein oligomerization ex vivo
Autor:
Marion eDelenclos, Teodora eTrendafilova, Daryl R Jones, Simon eMoussaud, Ann Marie eBaine, Mei eYue, Warren D Hirst, Pamela J McLean
Publikováno v:
Frontiers in Neuroscience, Vol 9 (2016)
Alpha synuclein (αsyn) aggregates are associated with the pathogenesis of Parkinson’s disease and others related disorders. Although modulation of αsyn aggregation is an attractive therapeutic target, new powerful methodologies are desperately ne
Externí odkaz:
https://doaj.org/article/36f24f5922ca4f87941ffdef1124687b
