Výsledky vyhledávání

Elevated expression of Foxp3 in tumor-infiltrating Treg cells suppresses T-cell proliferation and contributes to gastric cancer progression in a COX-2-dependent manner

Autor: Tong tong Zhang, Jian Wang, Feng Min Zhang, Mei Xing Li, Lei Chen, Xiangliang Yuan, Hai Liang Ge, Dakang Xu, Ping Dong, Xing an Wang, Jian Xue, Li Song Shen

Publikováno v: Clinical Immunology. 134:277-288

The transcription factor Foxp3 plays a key role in CD4(+)CD25(+) regulatory T (Treg) cell function. A correlation has been shown between survival and the frequency of tumor-infiltrating Foxp3-positive Treg cells in cancer patients. However, few studi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355c98ebca09d417b05c56627b3dca16
https://doi.org/10.1016/j.clim.2009.10.005

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RNA interference targeting CML66, a novel tumor antigen, inhibits proliferation, invasion and metastasis of HeLa cells

Autor: Lisong Shen, Shujun Wang, Guohua Xie, Hui-zhen Zhang, Hailiang Ge, Zheng-Chun Liu, Yong Zhang, Ying Wang, Shu Jin, Qing-Fei Wang, Mei-xing Li

Publikováno v: Cancer Letters. 269:127-138

CML66 is a novel, promising tumor antigen; however, its biological roles remain unclear. In present study, we applied a short hairpin RNA triggered RNA interfering to suppress CML66 expression in HeLa cervical carcinoma cells. Knockdown of CML66 inhi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dcf54c968cd5cc722723d1a143f93d8
https://doi.org/10.1016/j.canlet.2008.04.035

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CD4(+)CD25(+)CD127(low/-) regulatory T cells express Foxp3 and suppress effector T cell proliferation and contribute to gastric cancers progression

Autor: Dakang Xu, Ding Feng Shen, Jian Wang, Feng Min Zhang, Jian Xue, Li Song Shen, Xiangliang Yuan, Mei Xing Li, Hai Liang Ge, Ping Dong

Publikováno v: Clinical immunology (Orlando, Fla.). 131(1)

Increased populations of regulatory T cells (Tregs) impair anti-tumor immunity. Recently, the transcription factor Foxp3 has been reported to play a key role in CD4(+)CD25(+) regulatory T cell function and represents a specific marker for these cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1777faf135c1ae2532a96265bd883331
https://pubmed.ncbi.nlm.nih.gov/19153062

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[The effects of tumor antigen gene OVA66 on biological characteristics of tumor cells]

Autor: Mei-xing, Li, Shu-jun, Wang, Ying, Wang, Hui-zhen, Zhang, Qiang, You, Guang-yan, Zhou, Hai-liang, Ge

Publikováno v: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. 22(2)

To explore the effects of tumor antigen gene OVA66 on the biological characteristics of tumor cells.The eukaryotic expression vector pcDNA3.1-mock and recombined vector pcDNA3.1-OVA66 were transfected into hepatoma cell line SMMC-7721 by LipofectAMIN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a3fa1a1657c97f440f174b917c65c52a
https://pubmed.ncbi.nlm.nih.gov/16507255

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Akademický článek

Plasmon-Enhanced Electrochemiluminescence for Nucleic Acid Detection Based on Gold Nanodendrites.

Autor: Mei-Xing Li, Qiu-Mei Feng, Zhen Zhou, Wei Zhao, Jing-Juan Xu, Hong-Yuan Chen

Publikováno v: Analytical Chemistry; 1/16/2018, Vol. 90 Issue 2, p1340-1347, 8p

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[Identification of a novel HLA-A2-restrictive CTL epitope of an ovary cancer-associated antigen OVA66]

Autor: Shu, Jin, Ying, Wang, Shu-jun, Wang, Hui-zhen, Zhang, Mei-xing, Li, Ying, Chen, Hai-liang, Ge

Publikováno v: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. 21(2)

To identify a novel HLA-A2-restrictive CTL epitope of an ovary cancer-associated antigen OVA66.Dendritic cells (DCs), induced from peripheral blood mononuclear cells(PBMCs) by cytokines, were confirmed by morphological observation and FACS. Mature DC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::15153fb262c53053742c1993a5250edf
https://pubmed.ncbi.nlm.nih.gov/15766414

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