Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Mei Dang"'
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
Background3-caffeoylquinic acid (3-CQA), a member of the chlorogenic acid family, possesses diverse pharmacological properties, such as scavenging, antioxidant, and antiapoptotic activity, rendering substantial value to alimentary consumables and the
Externí odkaz:
https://doaj.org/article/506a9e5b49a2404cbfc205b49837e783
Publikováno v:
Scientific African, Vol 23, Iss , Pp e02019- (2024)
Egg yolk immunoglobulin Y (IgY) is a promising class of antibodies with applications in several areas including food safety, disease diagnosis, prevention and treatment. The technology involving IgY manipulation is relatively simple, yet powerful, du
Externí odkaz:
https://doaj.org/article/11299cab9311442cb8448d38e4ded1e1
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
An NMR-centered approach demonstrates that the liquid-liquid phase separation behavior of the SARS-CoV-2 nucleocapsid (N) protein is modulated by competitive interactions with ATP and nucleic acids.
Externí odkaz:
https://doaj.org/article/267d4e46261347688e35b2d113ff9789
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
Probing ssDNA binding to TAR-DNA-binding protein-43 (TDP-43) prion-like domain (PLD) through NMR shows key interactions for nucleic acid to drive liquid-liquid phase separation (LLPS) of intrinsically-disordered proteins.
Externí odkaz:
https://doaj.org/article/4e92a078f7c0437ea9dc62815d3b2f1a
Autor:
Xiaoying Zhang, Murtala Bindawa Isah, Mei Dang, Patricia M. Morgan, Marcin Sienczyk, David Bradley, Pablo Chacana
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/030bd31296624e60b771472a88daab18
Publikováno v:
ACS Omega, Vol 7, Iss 3, Pp 2798-2808 (2022)
Externí odkaz:
https://doaj.org/article/658b5b65ca724bb9b7086133b7a67440
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Dang Mei et al. use NMR and microscopy approaches to examine how ATP impacts the liquid-liquid phase separation (LLPS) of prion-like domains in TDP-43, a RNA-binding protein that is implicated in ALS and other neurological disorders. Their results su
Externí odkaz:
https://doaj.org/article/f4adf49a14ff4b13b8c5014276353840
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract TDP-43 and hnRNPA1 contain tandemly-tethered RNA-recognition-motif (RRM) domains, which not only functionally bind an array of nucleic acids, but also participate in aggregation/fibrillation, a pathological hallmark of various human diseases
Externí odkaz:
https://doaj.org/article/eca78a45f8f6463b9a44674beaad4482
Publikováno v:
ACS Omega, Vol 5, Iss 40, Pp 25677-25686 (2020)
Externí odkaz:
https://doaj.org/article/27a6df04559f47c0b28bf63e81e2936a
Autor:
Mei Dang, Jianxing Song
Publikováno v:
QRB Discovery, Vol 2 (2021)
SARS-CoV-2 nucleocapsid (N) protein plays the essential roles in key steps of the viral life cycle, thus representing a top drug target. Functionality of N protein including liquid–liquid phase separation (LLPS) depends on its interaction with nucl
Externí odkaz:
https://doaj.org/article/b91799aca4874726b9edb703cc581487