Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Mei Chee Tai"'
Autor:
Weang-Kee Ho, Nur Tiara Hassan, Sook-Yee Yoon, Xin Yang, Joanna M.C. Lim, Nur Diana Binte Ishak, Peh Joo Ho, Eldarina A. Wijaya, Patsy Pei-Sze Ng, Craig Luccarini, Jamie Allen, Mei-Chee Tai, Jianbang Chiang, Zewen Zhang, Mee-Hoong See, Meow-Keong Thong, Yin-Ling Woo, Alison M. Dunning, Mikael Hartman, Cheng-Har Yip, Nur Aishah Mohd Taib, Douglas F. Easton, Jingmei Li, Joanne Ngeow, Antonis C. Antoniou, Soo-Hwang Teo
Publikováno v:
The Lancet Regional Health. Western Pacific, Vol 44, Iss , Pp 101017- (2024)
Summary: Background: Clinical management of Asian BRCA1 and BRCA2 pathogenic variants (PV) carriers remains challenging due to imprecise age-specific breast (BC) and ovarian cancer (OC) risks estimates. We aimed to refine these estimates using six mu
Externí odkaz:
https://doaj.org/article/98fce87ebcdf49c88046d79e3ec0f863
Autor:
Peh Joo Ho, Weang Kee Ho, Alexis J. Khng, Yen Shing Yeoh, Benita Kiat-Tee Tan, Ern Yu Tan, Geok Hoon Lim, Su-Ming Tan, Veronique Kiak Mien Tan, Cheng-Har Yip, Nur-Aishah Mohd-Taib, Fuh Yong Wong, Elaine Hsuen Lim, Joanne Ngeow, Wen Yee Chay, Lester Chee Hao Leong, Wei Sean Yong, Chin Mui Seah, Siau Wei Tang, Celene Wei Qi Ng, Zhiyan Yan, Jung Ah Lee, Kartini Rahmat, Tania Islam, Tiara Hassan, Mei-Chee Tai, Chiea Chuen Khor, Jian-Min Yuan, Woon-Puay Koh, Xueling Sim, Alison M. Dunning, Manjeet K. Bolla, Antonis C. Antoniou, Soo-Hwang Teo, Jingmei Li, Mikael Hartman
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background Family history, and genetic and non-genetic risk factors can stratify women according to their individual risk of developing breast cancer. The extent of overlap between these risk predictors is not clear. Methods In this case-onl
Externí odkaz:
https://doaj.org/article/a1cd5204e97c4a85a285a67209cba529
Autor:
Peh Joo Ho, Alexis J. Khng, Hui Wen Loh, Weang-Kee Ho, Cheng Har Yip, Nur Aishah Mohd-Taib, Veronique Kiak Mien Tan, Benita Kiat-Tee Tan, Su-Ming Tan, Ern Yu Tan, Swee Ho Lim, Suniza Jamaris, Yirong Sim, Fuh Yong Wong, Joanne Ngeow, Elaine Hsuen Lim, Mei Chee Tai, Eldarina Azfar Wijaya, Soo Chin Lee, Ching Wan Chan, Shaik Ahmad Buhari, Patrick M. Y. Chan, Juliana J. C. Chen, Jaime Chin Mui Seah, Wai Peng Lee, Chi Wei Mok, Geok Hoon Lim, Evan Woo, Sung-Won Kim, Jong Won Lee, Min Hyuk Lee, Sue K. Park, Alison M. Dunning, Douglas F. Easton, Marjanka K. Schmidt, Soo-Hwang Teo, Jingmei Li, Mikael Hartman
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-14 (2021)
Abstract Background Mutations in certain genes are known to increase breast cancer risk. We study the relevance of rare protein-truncating variants (PTVs) that may result in loss-of-function in breast cancer susceptibility genes on tumor characterist
Externí odkaz:
https://doaj.org/article/324c3e5f19e348da8ee1b7ac569530b9
Autor:
Weang-Kee Ho, Min-Min Tan, Nasim Mavaddat, Mei-Chee Tai, Shivaani Mariapun, Jingmei Li, Peh-Joo Ho, Joe Dennis, Jonathan P. Tyrer, Manjeet K. Bolla, Kyriaki Michailidou, Qin Wang, Daehee Kang, Ji-Yeob Choi, Suniza Jamaris, Xiao-Ou Shu, Sook-Yee Yoon, Sue K. Park, Sung-Won Kim, Chen-Yang Shen, Jyh-Cherng Yu, Ern Yu Tan, Patrick Mun Yew Chan, Kenneth Muir, Artitaya Lophatananon, Anna H. Wu, Daniel O. Stram, Keitaro Matsuo, Hidemi Ito, Ching Wan Chan, Joanne Ngeow, Wei Sean Yong, Swee Ho Lim, Geok Hoon Lim, Ava Kwong, Tsun L. Chan, Su Ming Tan, Jaime Seah, Esther M. John, Allison W. Kurian, Woon-Puay Koh, Chiea Chuen Khor, Motoki Iwasaki, Taiki Yamaji, Kiak Mien Veronique Tan, Kiat Tee Benita Tan, John J. Spinelli, Kristan J. Aronson, Siti Norhidayu Hasan, Kartini Rahmat, Anushya Vijayananthan, Xueling Sim, Paul D. P. Pharoah, Wei Zheng, Alison M. Dunning, Jacques Simard, Rob Martinus van Dam, Cheng-Har Yip, Nur Aishah Mohd Taib, Mikael Hartman, Douglas F. Easton, Soo-Hwang Teo, Antonis C. Antoniou
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Polygenic risk scores predict the likelihood that an individual will develop a certain cancer, however these are often specific for a given population. Here, the authors show that a risk score developed to assess the risk of breast cancer in European
Externí odkaz:
https://doaj.org/article/c4e3ab2174674348a51d28c57a00ccd1
Autor:
Subrata Sen, Ann M. Killary, Randall E. Brand, Anirban Maitra, Cristian Coarfa, Kimberly S. Kirkwood, Pamela L. Paris, Mark W. Hurd, Christine DeCapite, Gary Longton, Ying Huang, Kimal Rajapakshe, Mei Chee Tai, Suyu Liu, Rachel L. Dittmar
Supplementary Table #1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867fd9cc4ee7be096e0b5f05339f6df1
https://doi.org/10.1158/1940-6207.22533355.v1
https://doi.org/10.1158/1940-6207.22533355.v1
Autor:
Subrata Sen, Ann M. Killary, Randall E. Brand, Anirban Maitra, Cristian Coarfa, Kimberly S. Kirkwood, Pamela L. Paris, Mark W. Hurd, Christine DeCapite, Gary Longton, Ying Huang, Kimal Rajapakshe, Mei Chee Tai, Suyu Liu, Rachel L. Dittmar
Early detection of pancreatic ductal adenocarcinoma (PDAC) is key to improving patient outcomes; however, PDAC is usually diagnosed late. Therefore, blood-based minimally invasive biomarker assays for limited volume clinical samples are urgently need
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::421c59b3ca6b058d9ed07898352f8e55
https://doi.org/10.1158/1940-6207.c.6547039.v1
https://doi.org/10.1158/1940-6207.c.6547039.v1
Autor:
Subrata Sen, Ann M. Killary, Randall E. Brand, Anirban Maitra, Cristian Coarfa, Kimberly S. Kirkwood, Pamela L. Paris, Mark W. Hurd, Christine DeCapite, Gary Longton, Ying Huang, Kimal Rajapakshe, Mei Chee Tai, Suyu Liu, Rachel L. Dittmar
Supplemental Figure #1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::104b7760e3f4a72868cffea51315ea59
https://doi.org/10.1158/1940-6207.22533361.v1
https://doi.org/10.1158/1940-6207.22533361.v1
Predicting the Likelihood of Carrying a BRCA1 or BRCA2 Mutation in Asian Patients With Breast Cancer
Autor:
Boon Hong Ang, Weang Kee Ho, Eldarina Wijaya, Pui Yoke Kwan, Pei Sze Ng, Sook Yee Yoon, Siti Norhidayu Hasan, Joanna M.C. Lim, Tiara Hassan, Mei-Chee Tai, Jamie Allen, Andrew Lee, Nur Aishah Mohd Taib, Cheng Har Yip, Mikael Hartman, Swee Ho Lim, Ern Yu Tan, Benita K.T. Tan, Su-Ming Tan, Veronique K.M. Tan, Peh Joo Ho, Alexis J. Khng, Alison M. Dunning, Jingmei Li, Douglas F. Easton, Antonis C. Antoniou, Soo Hwang Teo
Publikováno v:
Journal of Clinical Oncology. 40:1542-1551
PURPOSE With the development of poly (ADP-ribose) polymerase inhibitors for treatment of patients with cancer with an altered BRCA1 or BRCA2 gene, there is an urgent need to ensure that there are appropriate strategies for identifying mutation carrie
Autor:
Weang-Kee Ho, Mei-Chee Tai, Joe Dennis, Xiang Shu, Jingmei Li, Peh Joo Ho, Iona Y. Millwood, Kuang Lin, Yon-Ho Jee, Su-Hyun Lee, Nasim Mavaddat, Manjeet K. Bolla, Qin Wang, Kyriaki Michailidou, Jirong Long, Eldarina Azfar Wijaya, Tiara Hassan, Kartini Rahmat, Veronique Kiak Mien Tan, Benita Kiat Tee Tan, Su Ming Tan, Ern Yu Tan, Swee Ho Lim, Yu-Tang Gao, Ying Zheng, Daehee Kang, Ji-Yeob Choi, Wonshik Han, Han-Byoel Lee, Michiki Kubo, Yukinori Okada, Shinichi Namba, Sue K. Park, Sung-Won Kim, Chen-Yang Shen, Pei-Ei Wu, Boyoung Park, Kenneth R. Muir, Artitaya Lophatananon, Anna H. Wu, Chiu-Chen Tseng, Keitaro Matsuo, Hidemi Ito, Ava Kwong, Tsun L. Chan, Esther M. John, Allison W. Kurian, Motoki Iwasaki, Taiki Yamaji, Sun-Seog Kweon, Kristan J. Aronson, Rachel A. Murphy, Woon-Puay Koh, Chiea-Chuen Khor, Jian-Min Yuan, Rajkumar Dorajoo, Robin G. Walters, Zhengming Chen, Liming Li, Jun Lv, Keum-Ji Jung, Peter Kraft, Paul D.B. Pharoah, Alison M. Dunning, Jacques Simard, Xiao-Ou Shu, Cheng-Har Yip, Nur Aishah Mohd Taib, Antonis C. Antoniou, Wei Zheng, Mikael Hartman, Douglas F. Easton, Soo-Hwang Teo
Publikováno v:
Genetics in Medicine. 24:586-600
Purpose Non-European populations are under-represented in genetics studies, hindering clinical implementation of breast cancer polygenic risk scores (PRSs). We aimed to develop PRSs using the largest available studies of Asian ancestry and to assess
Autor:
Mei-Chee Tai, Leonidas E. Bantis, Gargy Parhy, Taketo Kato, Ichidai Tanaka, Chi-Wan Chow, Junya Fujimoto, Carmen Behrens, Tetsunari Hase, Koji Kawaguchi, Johannes F. Fahrmann, Edwin Ostrin, Kohei Yokoi, Toyofumi F. Chen-Yoshikawa, Yoshinori Hasegawa, Samir M. Hanash, Ignacio I. Wistuba, Ayumu Taguchi
Publikováno v:
Cancer Research. 83:3744-3744
Background: Early-stage lung adenocarcinoma (LUAD) patients have substantial risk for recurrence and disease-related death. Cisplatin-based adjuvant chemotherapy remains the standard for care of LUAD patients who have undergone surgical resection wit