Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mehtap Kılıç Eren"'
Publikováno v:
Tıpta Yenilikçi Yaklaşımlar Dergisi. 1:1-10
Chemotherapeutic agents that cause DNA damage also induce cellular senescence known as therapy-induced senescence (TIS). Cells undergoing senescence may exert detrimental effects by promoting tumor progression in healthy cells or supporting metastase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44be965ad2bbcda655ae0c4354d32bab
https://doi.org/10.29329/jiam.2020.299.1
https://doi.org/10.29329/jiam.2020.299.1
Autor:
Mehtap Kılıç Eren
Publikováno v:
International Journal of Innovative Approaches in Science Research. 4:191-204
Healthy cells maintain genome integrity by activating a conserved DNA damage response (DDR) pathway that halts the progression of the cell cycle and activates DNA repair. Molecular disorders preventing DDR functioning properly often predispose to can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a7c81655e37bb178c5ae6ce3d5284c3
https://doi.org/10.29329/ijiasr.2020.312.7
https://doi.org/10.29329/ijiasr.2020.312.7
Autor:
Nur Betül Kartal, Mehtap Kılıç Eren
Publikováno v:
International Journal of Innovative Approaches in Science Research. 3:83-97
Saglikli hucreler genom butunlugunu, hucre dongusundeki ilerleyisi erteleyen/durduran ve DNA tamirini devreye sokan korunmus bir DNA hasari yaniti yolagini aktive ederek surdururler. Bu sinyal yolaginin duzgun olarak calismasini engelleyen molekuler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::722382b56b6e49e2abbeb8ad529ae8eb
https://doi.org/10.29329/ijiasr.2019.213.2
https://doi.org/10.29329/ijiasr.2019.213.2
Publikováno v:
International Journal of Innovative Approaches in Science Research. 2:152-161
Dogal oldurucu hucreler (Natural Killer: NK) bircok aktivator ve inhibitor reseptorlere sahip olan CD3- CD56+ lenfositlerdir. NK hucrelerinin kanser tedavisine yonelik olarak otolog ve allojenik kullanimlari soz konusudur. Bunun yani sira ticari olar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::834d95494ee80b8795b1bdf69fe262e1
https://doi.org/10.29329/ijiasr.2018.173.4
https://doi.org/10.29329/ijiasr.2018.173.4
Publikováno v:
International Journal of Innovative Approaches in Science Research. 2:25-40
Cancer stem cells (CSCs) are a collection of small numbers of cells that have the potential to induce all cell types within the tumor mass and have self-renewal capacity. Today, the reasons for the failure of conventional cancer therapies lie in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ee2f62591405d6142b82b64aff387b9
https://doi.org/10.29329/ijiasr.2018.132.3
https://doi.org/10.29329/ijiasr.2018.132.3
Autor:
Mehtap Kılıç Eren
Publikováno v:
International Journal of Innovative Approaches in Science Research. 1:9-19
Kanser kok hucreleri, bir tumor icindeki nadir olumsuz hucrelerdir ve bolunerek kendiliginden yenilenebilir ve tumoru olusturan bircok hucre turune koken olusturabilir. Bu hucreler cesitli insan tumorlerinde bulunmaktadir ve kanser tedavisi icin hede
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6f70ad863d067cf678861ca7afa2257
https://doi.org/10.29329/ijiasr.2017.99.2
https://doi.org/10.29329/ijiasr.2017.99.2
Autor:
Rauf Onur Ek, Gokhan Cesur, Ferhat Şirinyıldız, Kemal Ergin, Mehtap Kılıç Eren, Umut Gök Balcı, Yuksel Yildiz, Kurtuluş Öngel, Erdal Eren
Publikováno v:
Hormone Molecular Biology and Clinical Investigation. 36
PurposeThe aim of the study was to evaluate the effects of prenatal hypothyroidism on neonatal rats by the way of activity-dependent neuroprotective factor (ADNF) expression.MethodsTwenty-one Wistar albino neonatal rats were divided into two subgroup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b53e83e3a2e53b58dbc7f63e262489c1
https://doi.org/10.1515/hmbci-2017-0069
https://doi.org/10.1515/hmbci-2017-0069
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124837 (2015)
PLoS ONE
PLoS ONE
The natural polyphenolic compound resveratrol (3,4,5-trihydroxy-trans-stilbene) has broad spectrum health beneficial activities including antioxidant, anti-inflammatory, anti-aging, anti-cancer, cardioprotective, and neuroprotective effects. Remarkab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a150f4c5185692db810c300dc1e25f
http://europepmc.org/articles/PMC4414559?pdf=render
http://europepmc.org/articles/PMC4414559?pdf=render
Autor:
Mehtap Kılıç Eren, Vedrana Tabor
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 7, p e101064 (2014)
PLoS ONE, Vol 9, Iss 7, p e101064 (2014)
Oncogene induced senescence (OIS) is a sustained anti-proliferative response acutely induced in primary cells via activation of mitogenic oncogenes such as Ras/BRAF. This mechanism acts as an initial barrier preventing normal cells transformation int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c55deea687df05a0fa8ae5d0acaabca
https://doi.org/10.1371/journal.pone.0101064
https://doi.org/10.1371/journal.pone.0101064
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124837 (2015)
The natural polyphenolic compound resveratrol (3,4,5-trihydroxy-trans-stilbene) has broad spectrum health beneficial activities including antioxidant, anti-inflammatory, anti-aging, anti-cancer, cardioprotective, and neuroprotective effects. Remarkab
Externí odkaz:
https://doaj.org/article/0ad8c11c021d434cb458b218ef2e41ea