Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Mehrshad Pakdel"'
Publikováno v:
Bio-Protocol, Vol 11, Iss 5 (2021)
Monitoring vesicle trafficking is an excellent tool for the evaluation of protein dynamics in living cells. Such study is key for the understanding of protein sorting and secretion. Recent developments in microscopy, as well as new methodologies deve
Externí odkaz:
https://doaj.org/article/2e0538274cd34beea795a08e2fd81e40
Publikováno v:
Bio-Protocol, Vol 11, Iss 6 (2021)
More than 30% of the total amount of proteins synthesized in mammalian cells follow the secretory pathway in order to mature and be properly sorted to their final destinations. Among several methodologies that describe live-cell monitoring of vesicle
Externí odkaz:
https://doaj.org/article/5dcbdf9489a6439c95d4bdefca5da5d7
Autor:
Manuel Alonso Y Adell, Simona M Migliano, Srigokul Upadhyayula, Yury S Bykov, Simon Sprenger, Mehrshad Pakdel, Georg F Vogel, Gloria Jih, Wesley Skillern, Reza Behrouzi, Markus Babst, Oliver Schmidt, Michael W Hess, John AG Briggs, Tomas Kirchhausen, David Teis
Publikováno v:
eLife, Vol 6 (2017)
The ESCRT machinery mediates reverse membrane scission. By quantitative fluorescence lattice light-sheet microscopy, we have shown that ESCRT-III subunits polymerize rapidly on yeast endosomes, together with the recruitment of at least two Vps4 hexam
Externí odkaz:
https://doaj.org/article/bfacb53d082646339785a5fcad761fe0
Publikováno v:
Bio Protoc
More than 30% of the total amount of proteins synthesized in mammalian cells follow the secretory pathway in order to mature and be properly sorted to their final destinations. Among several methodologies that describe live-cell monitoring of vesicle
Publikováno v:
Bio Protoc
Monitoring vesicle trafficking is an excellent tool for the evaluation of protein dynamics in living cells. Such study is key for the understanding of protein sorting and secretion. Recent developments in microscopy, as well as new methodologies deve
Autor:
Tobias Karl Heinz Hecht, Renate Gautsch, Ismael Sánchez-González, Mehrshad Pakdel, Julia von Blume, Birgit Blank, Natalia Pacheco-Fernandez, Angelika Hausser, Kathrin Weber, Franck Perez, Gisela Beck, Stefan Linder, Mai Ly Tran
Publikováno v:
The Journal of Cell Biology : JCB
Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2020, 219, ⟨10.1083/jcb.201907058⟩
The Journal of Cell Biology
Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2020, 219, ⟨10.1083/jcb.201907058⟩
The Journal of Cell Biology
Trafficking of matrix metalloproteinases (MMPs) through the Golgi remains enigmatic in the field. Pacheco-Fernandez et al. find that nucleobindin-1 (NUCB1), a cis-Golgi localized Ca2+-binding protein, plays a major role in this process by binding to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db30940044611ea100bc860a4e2adc15
https://hdl.handle.net/21.11116/0000-0007-4BE7-121.11116/0000-0007-4BE9-F
https://hdl.handle.net/21.11116/0000-0007-4BE7-121.11116/0000-0007-4BE9-F
Autor:
Julia von Blume, Mehrshad Pakdel
Publikováno v:
Molecular Biology of the Cell. 29:235-240
Sorting of soluble proteins for transport to intracellular compartments and for secretion from cells is essential for cell and tissue homeostasis. The trans-Golgi network (TGN) is a major sorting station that sorts secretory proteins into specific ca
Autor:
Bianca Habermann, Alvaro H. Crevenna, Julia von Blume, Andreas Maiser, Gisela Beck, Jens Prescher, Don C. Lamb, Christine Kienzle, Kira Bartnik, Derya Emin, Heinrich Leonhardt, Mehrshad Pakdel, Birgit Blank
Publikováno v:
The Journal of Cell Biology
Crevenna et al. examine the mechanism by which secretory cargoes are segregated at the trans-Golgi network (TGN) for release into the extracellular space. The authors demonstrate that Ca2+-dependent changes in Cab45 oligomerization mediate sorting of
Autor:
Mehrshad, Pakdel, Julia, von Blume
Publikováno v:
Molecular Biology of the Cell
Sorting of soluble proteins for transport to intracellular compartments and for secretion from cells is essential for cell and tissue homeostasis. The trans-Golgi network (TGN) is a major sorting station that sorts secretory proteins into specific ca
Autor:
David Teis, Martin Müller, Georg F. Vogel, Herbert Lindner, Michael W. Hess, Mehrshad Pakdel, Manuel Alonso Y Adell
Publikováno v:
The Journal of Cell Biology
Vps4 both recycles ESCRT-III subunits and cooperates with ESCRT-III to drive distinct membrane remodeling steps that lead to efficient membrane scission during the biogenesis of multivesicular bodies.
Five endosomal sorting complexes required fo
Five endosomal sorting complexes required fo