Breastfeeding and Neonatal Age Influence Neutrophil-Driven Ontogeny of Blood Cell Populations in the First Week of Human Life

Autor: Sebastiano Montante, Rym Ben-Othman, Nelly Amenyogbe, Asimenia Angelidou, Anita van den Biggelaar, Bing Cai, Yixuan Chen, Alansana Darboe, Joann Diray-Arce, Rebecca Ford, Olubukola Idoko, Amy Lee, Mandy Lo, Kerry McEnaney, Mehrnoush Malek, David Martino, Geraldine Masiria, Oludare A. Odumade, William Pomat, Casey Shannon, Kinga Smolen, The EPIC Consortium, Al Ozonoff, Peter Richmond, Scott Tebbutt, Ofer Levy, Beate Kampmann, Ryan Brinkman, Tobias Kollmann

Publikováno v: Journal of Immunology Research, Vol 2024 (2024)

The first few days of life are characterized by rapid external and internal changes that require substantial immune system adaptations. Despite growing evidence of the impact of this period on lifelong immune health, this period remains largely uncha

Externí odkaz: https://doaj.org/article/3ad7341bf7814ea7b8cbe60b995dd7c0

Dynamic molecular changes during the first week of human life follow a robust developmental trajectory

Autor: Tue Tb Bennike, Tobias R. Kollmann, Alansana Darboe, Peter Richmond, Hanno Steen, Ofer Levy, Asimenia Angelidou, Mehrnoush Malek, Casey P. Shannon, Daniel He, Anita Ahj van den Biggelaar, Guzman Sanchez-Schmitz, Ahwon Lee, Cai Bing, Elishia Roberts, Kim-Anh Lê Cao, Jorjoh Ndure, Joann Diray-Arce, Davide Ferrari, Reza Falsafi, Jainaba Njie-Jobe, Kinga K. Smolen, Momoudou Cox, Geraldine Masiria, William Ws Pomat, Rym Ben-Othman, Amrit Singh, Ryan Rr Brinkman, Erin E. Gill, John Paul Matlam, Scott Sj Tebbutt, Nelly Amenyogbe, Samuel Sj Hinshaw, Rebecca Ford, Robert E. W. Hancock, Daniel Dj Harbeson, G Saleu, Simon Sd van Haren, Matthew Ma Pettengill, Al Ozonoff, Olubukola Ot Idoko, Beate Kampmann, Wendy Kirarock

Publikováno v: Lee, A H, Shannon, C P, Amenyogbe, N, Bennike, T B, Diray-Arce, J, Idoko, O T, Gill, E E, Ben-Othman, R, Pomat, W S, van Haren, S D, Cao, K A L, Cox, M, Darboe, A, Falsafi, R, Ferrari, D, Harbeson, D J, He, D, Bing, C, Hinshaw, S J, Ndure, J, Njie-Jobe, J, Pettengill, M A, Richmond, P C, Ford, R, Saleu, G, Masiria, G, Matlam, J P, Kirarock, W, Roberts, E, Malek, M, Sanchez-Schmitz, G, Singh, A, Angelidou, A, Smolen, K K, The EPIC Consortium, Brinkman, R R, Ozonoff, A, Hancock, R E W, van den Biggelaar, A H J, Steen, H, Tebbutt, S J, Kampmann, B, Levy, O & Kollmann, T R 2019, ' Dynamic molecular changes during the first week of human life follow a robust developmental trajectory ', Nature Communications, vol. 10, no. 1, 1092 . https://doi.org/10.1038/s41467-019-08794-x
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature communications, 10 (1

Systems biology can unravel complex biology but has not been extensively applied to human newborns, a group highly vulnerable to a wide range of diseases. We optimized methods to extract transcriptomic, proteomic, metabolomic, cytokine/chemokine, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2932549b71532d1598206a46d8ed0bad
https://vbn.aau.dk/da/publications/a883a18f-2630-4edf-a9b4-aa008fca0d0c

Implementation and Validation of an Automated Flow Cytometry Analysis Pipeline for Human Immune Profiling

Autor: Mehrnoush Malek, Yoshinobu Koguchi, Christopher Dubay, Valerie Conrad, Ryan R. Brinkman, William L. Redmond

Publikováno v: Cytometry. Part A : the journal of the International Society for Analytical Cytology. 95(2)

Automated reagent preparation, sample processing, and data acquisition have increased the rate at which flow cytometry data can be generated. Furthermore, advances in technology and flow cytometry instrumentation continually increase the complexity a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5475ea44c7d924006800bddb3e2dd8c
https://pubmed.ncbi.nlm.nih.gov/30549412

A benchmark for evaluation of algorithms for identification of cellular correlates of clinical outcomes

Autor: Greg Finak, Geoffrey J. McLachlan, Sofie Van Gassen, Raphael Gottardo, Celine Vens, Peng Qiu, Pratip K. Chattopadhyay, Dong Tong, Maria Chikina, Kui Wang, Miron B. Kursa, Garry P. Nolan, Nima Aghaeepour, Tom Dhaene, Richard H. Scheuermann, Yvan Saeys, Yu Qian, Slawomir Walkowiak, Mehrnoush Malek, Bart N. Lambrecht, Rick Stanton, Ryan R. Brinkman, Tim R. Mosmann

Publikováno v: Cytometry Part A. 89:16-21

The Flow Cytometry: Critical Assessment of Population Identification Methods (FlowCAP) challenges were established to compare the performance of computational methods for identifying cell populations in multidimensional flow cytometry data. Here we r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4e8bde5267c7673d4aad17ba9ca0b851
https://doi.org/10.1002/cyto.a.22732

A benchmark for evaluation of algorithms for identification of cellular correlates of clinical outcomes

Autor: Nima, Aghaeepour, Pratip, Chattopadhyay, Maria, Chikina, Tom, Dhaene, Sofie, Van Gassen, Miron, Kursa, Bart N, Lambrecht, Mehrnoush, Malek, G J, McLachlan, Yu, Qian, Peng, Qiu, Yvan, Saeys, Rick, Stanton, Dong, Tong, Celine, Vens, Sławomir, Walkowiak, Kui, Wang, Greg, Finak, Raphael, Gottardo, Tim, Mosmann, Garry P, Nolan, Richard H, Scheuermann, Ryan R, Brinkman

Publikováno v: Cytometry. Part A : the journal of the International Society for Analytical Cytology. 89(1)

The Flow Cytometry: Critical Assessment of Population Identification Methods (FlowCAP) challenges were established to compare the performance of computational methods for identifying cell populations in multidimensional flow cytometry data. Here we r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::224b2d8ffa29e77638928367f1c649f7
https://pubmed.ncbi.nlm.nih.gov/26447924