Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Mehrnaz Jafarian-Tehrani"'
Autor:
Gemma Llufriu-Dabén, Alex Carrete, Elena Chierto, Jo Mailleux, Emeline Camand, Anne Simon, Tim Vanmierlo, Christiane Rose, Bernadette Allinquant, Jerome J.A. Hendriks, Charbel Massaad, Delphine Meffre, Mehrnaz Jafarian-Tehrani
Publikováno v:
Neurobiology of Disease, Vol 109, Iss , Pp 11-24 (2018)
Remyelination is an endogenous regenerative process of myelin repair in the central nervous system (CNS) with limited efficacy in demyelinating disorders. As strategies enhancing endogenous remyelination become a therapeutic challenge, we have focuse
Externí odkaz:
https://doaj.org/article/c262bbe9326f41d4820553374b0a7fec
Publikováno v:
Neuroscience. 455
Demyelination is a well-known pathological process in CNS disorders such as multiple sclerosis (MS). It provokes progressive axonal degeneration and functional impairments and no efficient therapy is presently available to combat such insults. Recent
Autor:
Mehrnaz Jafarian-Tehrani, Delphine Meffre, Francesca Sapone, Giulia Cristinziano, Elena Chierto
Publikováno v:
Reactive Oxygen Species.
Oligodendrocytes are the key cells for the myelin synthesis in the central nervous system (CNS). They are sensitive to oxidative stress because of their lipid-rich membranes and their limited antioxidant defense against an excessive production of rea
Autor:
Mehrnaz Jafarian-Tehrani, Anne Simon, Gemma Llufriu-Dabén, Christiane Rose, Jo Mailleux, Delphine Meffre, Emeline Camand, Bernadette Allinquant, Alex Carrete, Elena Chierto, Jerome J. A. Hendriks, Charbel Massaad, Tim Vanmierlo
Publikováno v:
Neurobiology of Disease, Vol 109, Iss, Pp 11-24 (2018)
Remyelination is an endogenous regenerative process of myelin repair in the central nervous system (CNS) with limited efficacy in demyelinating disorders. As strategies enhancing endogenous remyelination become a therapeutic challenge, we have focuse
Autor:
Didier Borderie, Mehrnaz Jafarian-Tehrani, Elena Chierto, Giulia Cristinziano, Delphine Meffre, Francesca Castoldi, François Etienne, Anne Simon, François Rannou, Barclay Morrison, Francesca Sapone, Charbel Massaad, Alex Carrete
Publikováno v:
Molecular Neurobiology
Increasing findings suggest that demyelination may play an important role in the pathophysiology of brain injury, but the exact mechanisms underlying such damage are not well known. Mechanical tensile strain of brain tissue occurs during traumatic br
Publikováno v:
Journal of neuroscience methods. 311
Background Traumatic brain injury (TBI) induces significant cognitive deficits correlated with white matter injury, involving both axonal and myelin damage. Several models of TBI ex vivo are available to mimic focal impact on brain tissue. However, n
Autor:
Eleni Siopi, Maria-Paz Viveros, Catherine Marchand-Leroux, Ana Belen Lopez-Rodriguez, Luis M. Garcia-Segura, David P. Finn, Mehrnaz Jafarian-Tehrani
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Traumatic brain injury (TBI) and its consequences represent one of the leading causes of death in young adults. This lesion mediates glial activation and the release of harmful molecules and causes brain edema, axonal injury, and functional impairmen
Autor:
Mehrnaz Jafarian-Tehrani, Michel Plotkine, Gemma Llufriu-Dabén, Catherine Marchand-Leroux, Francesca Fanucchi, Eleni Siopi
Publikováno v:
Neuroscience Letters. 511:110-115
Comorbidity of cognitive and stress disorders is a common clinical sequel of traumatic brain injury (TBI) that is essentially determined by the site and severity of the insult, but also by the extent of the ensuing neuroinflammatory response. The pre
Autor:
Mehrnaz Jafarian-Tehrani, Michel Plotkine, Eleni Siopi, Silvia Calabria, Catherine Marchand-Leroux
Publikováno v:
Journal of Neurotrauma. 29:354-361
Permanent olfactory dysfunction can often arise after traumatic brain injury (TBI) and while one of the main causes is the immediate loss of neurons in the olfactory bulb (OB), the emergent neuroinflammatory environment following TBI may further prom
Autor:
Eleni Siopi, Mehrnaz Jafarian-Tehrani, Angelo H. Cho, Michel Plotkine, Nicole Croci, Catherine Marchand-Leroux, Shadi Homsi
Publikováno v:
Journal of Neurotrauma. 28:2135-2143
Traumatic brain injury (TBI) induces both focal and diffuse lesions that are concurrently responsible for the ensuing morbidity and mortality and for which no established treatment is available. It has been recently reported that an endogenous neurop