Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Mehrdad Rakaee"'
Autor:
Erna-Elise Paulsen, Sigve Andersen, Mehrdad Rakaee, Mona Irene Pedersen, Ana Paola Lombardi, Mette Pøhl, Thomas Kilvaer, Lill-Tove Busund, Francesco Pezzella, Tom Donnem
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionNon-small cell lung carcinomas (NSCLC) exhibit different microvessel patterns (MVPs). Basal (BA), diffuse (DA) and papillary (PA) patterns show signs of angiogenesis (new blood vessels), while an alveolar pattern indicates that tumors are
Externí odkaz:
https://doaj.org/article/5be10fff34704cc99defbb4c7f28bedd
Autor:
Lorenzo Nibid, Carlo Greco, Ermanno Cordelli, Giovanna Sabarese, Michele Fiore, Charles Z. Liu, Edy Ippolito, Rosa Sicilia, Marianna Miele, Matteo Tortora, Chiara Taffon, Mehrdad Rakaee, Paolo Soda, Sara Ramella, Giuseppe Perrone
Publikováno v:
PLoS ONE, Vol 18, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/a159c855732e4e1682f97826fbed86ef
Autor:
Thomas Karsten Kilvaer, Mehrdad Rakaee, Turid Hellevik, Jørg Vik, Luigi De Petris, Tom Donnem, Carina Strell, Arne Ostman, Lill-Tove Rasmussen Busund, Inigo Martinez-Zubiaurre
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract Preclinical evidence suggests that stromal expression of platelet-derived growth factor receptors (PDGFRs) stimulates tumor development and diminishes intratumoral drug uptake. In non-small cell lung cancer (NSCLC), the clinical relevance of
Externí odkaz:
https://doaj.org/article/41323426fa774eeb847449f5998643f9
Autor:
Mehrdad Rakaee, Lill-Tove Rasmussen Busund, Simin Jamaly, Erna-Elise Paulsen, Elin Richardsen, Sigve Andersen, Samer Al-Saad, Roy M. Bremnes, Tom Donnem, Thomas K. Kilvaer
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 3, Pp 282-293 (2019)
Macrophages are important inflammatory cells that regulate innate and adaptive immunity in cancer. Tumor-associated macrophages (TAMs) are thought to differentiate into two main phenotypes: proinflammatory M1 and protumorigenic M2. Currently, the pro
Externí odkaz:
https://doaj.org/article/53a89b2d5db84ad78ed21820aac99571
Autor:
Thomas Karsten Kilvaer, Mehrdad Rakaee, Turid Hellevik, Arne Østman, Carina Strell, Roy M Bremnes, Lill-Tove Busund, Tom Dønnem, Inigo Martinez-Zubiaurre
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192157 (2018)
Selective targeting of cancer-associated fibroblasts (CAFs) has been proposed to synergize with immune-checkpoint inhibitors. While the roles of CAFs in cancer development are well described, their immune-regulatory properties remain incompletely und
Externí odkaz:
https://doaj.org/article/8cf7b39f00194f3a90cd9c5174b52d63
Autor:
Erna-Elise Paulsen, Thomas Kilvaer, Mehrdad Rakaee Khanehkenari, Ramona Johansen Maurseth, Samer Al-Saad, Sigurd M. Hald, Khalid Al-Shibli, Sigve Andersen, Elin Richardsen, Lill-Tove Busund, Roy Bremnes, Tom Donnem
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 11, Pp 839-848 (2015)
Tumor-infiltrating lymphocytes (TILs) are vital in limiting cancer progression and may supplement the TNM classification. CD45RO+ memory TILs show major prognostic impact in various malignancies but have not been extensively explored in non–small c
Externí odkaz:
https://doaj.org/article/a838926a79934471a1af49ed71ea4c6d
Autor:
Elin Richardsen, Sigve Andersen, Samer Al-Saad, Mehrdad Rakaee, Yngve Nordby, Mona Irene Pedersen, Nora Ness, Thea Grindstad, Ingeborg Movik, Tom Dønnem, Roy Bremnes, Lill-Tove Busund
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0186852 (2017)
The tumor proliferation index marker Ki-67 is strongly associated with tumor cell proliferation, growth and progression, and is widely used in routine clinicopathological investigation. Prostate cancer is a complex multifaceted and biologically heter
Externí odkaz:
https://doaj.org/article/bf8289c3f6944f8aa7c181bed2207d2a
Autor:
Sigve Andersen, Elin Richardsen, Mehrdad Rakaee, Helena Bertilsson, Roy Bremnes, Magne Børset, Lill-Tove Busund, Tobias Slørdahl
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0189000 (2017)
Prostate cancer (PC) stratification needs new prognostic tools to reduce overtreatment. Phosphatase of regenerating liver (PRL-3) is a phosphatase found at high levels in several cancer types, where its expression is associated with survival. A recen
Externí odkaz:
https://doaj.org/article/1cbfbcc1891e4ec1a1099e61a1ea74fb
Autor:
Thomas K Kilvaer, Mehrdad Rakaee Khanehkenari, Turid Hellevik, Samer Al-Saad, Erna-Elise Paulsen, Roy M Bremnes, Lill-Tove Busund, Tom Donnem, Inigo Z Martinez
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134965 (2015)
BackgroundCancer Associated Fibroblasts (CAFs) are thought to regulate tumor growth and metastasis. Fibroblast Activating Protein 1 (FAP-1) is a marker for fibroblast activation and by many recognized as the main marker of CAFs. Alpha Smooth Muscle A
Externí odkaz:
https://doaj.org/article/35c031e2621049f9999f832e29f6aaac
Autor:
Biagio Ricciuti, Arielle Elkrief, Joao Alessi, Xinan Wang, Yvonne Li, Hersh Gupta, Daniel M. Muldoon, Arrien A. Bertram, Federica Pecci, Giuseppe Lamberti, Alessandro Di Federico, Adriana Barrichello, Victor R. Vaz, Malini Gandhi, Elinton Lee, Geoffrey I. Shapiro, Hyesun Park, Mizuki Nishino, James Lindsay, Kristen D. Felt, Bijaya Sharma, Andrew D. Cherniack, Scott Rodig, Daniel R. Gomez, Narek Shaverdian, Mehrdad Rakaee, Chaitanya Bandlamudi, Marc Ladanyi, Pasi A. Janne, Adam J. Schoenfeld, Lynette M. Sholl, Mark M. Awad, Michael L. Cheng
Publikováno v:
Clinical Cancer Research. :OF1-OF11
Purpose: ATM is the most commonly mutated DNA damage and repair gene in non–small cell lung cancer (NSCLC); however, limited characterization has been pursued. Experimental Design: Clinicopathologic, genomic, and treatment data were collected for 5