Zobrazeno 1 - 10
of 384
pro vyhledávání: '"Mehrdad Nikfarjam"'
Autor:
Lin Li, Jessica Kasza, Ariadna Recasens, Liane Ioannou, Elysia Greenhill, Neil Merrett, David Cavallucci, Samantha Ellis, Helen Madgwick, Hyun Soo Ko, Lorraine Chantrill, Benjamin Loveday, Mehrdad Nikfarjam, Daniel Croagh, Jessica Yang, Andrew Dwyer, John Zalcberg, Charles Pilgrim, SCANPatient Authorship Group
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background Complete surgical removal of pancreatic ductal adenocarcinoma (PDAC) is central to all curative treatment approaches for this aggressive disease, yet this is only possible in patients technically amenable to resection. Hence, an a
Externí odkaz:
https://doaj.org/article/8155d023b1684df7b7f5d68e3d09af14
Autor:
Yi Ma, Chelsea Dumesny, Li Dong, Ching-Seng Ang, Khashayar Asadi, Yifan Zhan, Mehrdad Nikfarjam, Hong He
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal types of cancer, and KRAS oncogene occurs in over 90% of cases. P21-activated kinases (PAK), containing six members (PAK1 to 6), function downstream of KRAS. PAK1 an
Externí odkaz:
https://doaj.org/article/9e0cfb4ddaad4b95964ffbedda73cc71
Autor:
Angelica Armellini, Shaun Chew, Samuel Johnston, Vijayaragavan Muralidharan, Mehrdad Nikfarjam, Laurence Weinberg
Publikováno v:
BMC Research Notes, Vol 17, Iss 1, Pp 1-7 (2024)
Abstract Objective Postoperative complications following major abdominal surgeries is a pressing concern for hospital care and health economics. Given the paucity of available cost data for patients undergoing major abdominal surgery, we evaluated th
Externí odkaz:
https://doaj.org/article/7ca78ee9bfeb47e892319398afbab0f6
Autor:
Bradly Carp, Laurence Weinberg, Luke R. Fletcher, Jake V. Hinton, Adam Cohen, Hugh Slifirski, Peter Le, Stephen Woodford, Shervin Tosif, David Liu, Vijaragavan Muralidharan, Marcos V. Perini, Mehrdad Nikfarjam, Dong-Kyu Lee
Publikováno v:
Frontiers in Surgery, Vol 11 (2024)
BackgroundThe concept of a “textbook outcome” is emerging as a metric for ideal surgical outcomes. We aimed to evaluate the impact of an advanced haemodynamic monitoring (AHDM) algorithm on achieving a textbook outcome in patients undergoing hepa
Externí odkaz:
https://doaj.org/article/b2fc5e02fd4741a9a6ba33c1fc5e2a86
Publikováno v:
Cells, Vol 12, Iss 23, p 2692 (2023)
Angiogenesis has been associated with numbers of solid tumours. Anti-angiogenesis drugs starve tumours of nutrients and oxygen but also make it difficult for a chemo reagent to distribute into a tumour, leading to aggressive tumour growth. Anti-angio
Externí odkaz:
https://doaj.org/article/ba2cb889f6a34c8493cf2eb9b7d59786
Autor:
Vidhura Ratnasekara, Laurence Weinberg, Samuel Anthony Johnston, Luke Fletcher, Patrick Nugraha, Daniel Robert Anthony Cox, Raymond Hu, Ilonka Meyer, Osamu Yoshino, Marcos Vinius Perini, Vijayaragavan Muralidharan, Mehrdad Nikfarjam, Dong-Kyu Lee
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0291108 (2023)
IntroductionThe optimal analgesic modality for patients undergoing hepato-pancreato-biliary (HPB) surgery remains unknown. The analgesic effects of a multimodal intrathecal analgesia (MITA) technique of intrathecal morphine (ITM) in combination with
Externí odkaz:
https://doaj.org/article/d47a8e94d069420dae58762326f9472f
Publikováno v:
BMJ Open, Vol 12, Iss 12 (2022)
Introduction Despite advances in achieving low mortality rates with pancreaticoduodenectomy (PD), morbidity remains high. A key contributor to this morbidity is delayed gastric emptying (DGE) occurring with an incidence of up to 30%. The utility of a
Externí odkaz:
https://doaj.org/article/a950c182d5214fbe93e871e53c85df54
Autor:
Krithika Murali, Tanya M. Dwarte, Mehrdad Nikfarjam, Katherine M. Tucker, Rhys B. Vaughan, Marios Efthymiou, Allison Collins, Allan D. Spigelman, Lucinda Salmon, Amber L. Johns, David B. Williams, Martin B. Delatycki, Thomas John, Alina Stoita
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background The Australian Pancreatic Cancer Screening Program (APCSP) offers endoscopic ultrasound surveillance for individuals at increased risk of pancreatic ductal adenocarcinoma (PDAC) with all participants requiring assessment by a Fami
Externí odkaz:
https://doaj.org/article/268bc6e6fb0d40b4bc97db44e48c0587
Autor:
Laurence Weinberg, Vidhura Ratnasekara, Anthony T. Tran, Peter Kaldas, Tom Neal-Williams, Michael R. D’Silva, Jackson Hua, Sean Yip, Patryck Lloyd-Donald, Luke Fletcher, Ronald Ma, Marcos V. Perini, Mehrdad Nikfarjam, Dong-Kyu Lee
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
BackgroundUnderstanding the financial implications associated with the complications post-distal pancreatectomy (DP) may be beneficial for the future optimisation of postoperative care pathways and improved cost-efficiency. The primary outcome of thi
Externí odkaz:
https://doaj.org/article/fc1841cf57634b6b840f6d4022f711e3
Publikováno v:
Translational Oncology, Vol 16, Iss , Pp 101329- (2022)
Over 95% of Pancreatic ductal adenocarcinomas (PDA) carry mutations in the oncogene KRas which has been proven to be a difficult drug target. P21-activated kinase 4 (PAK4), acts downstream of KRas, and is overexpressed in PDA contributing to its grow
Externí odkaz:
https://doaj.org/article/15508468749e41bbadc73419c2427e86