Výsledky vyhledávání - "Mehrdad Matloubian"

Akademický článek

Using the technology acceptance model to assess clinician perceptions and experiences with a rheumatoid arthritis outcomes dashboard: qualitative study

Autor: Catherine Nasrallah, Cherish Wilson, Alicia Hamblin, Cammie Young, Lindsay Jacobsohn, Mary C. Nakamura, Andrew Gross, Mehrdad Matloubian, Judith Ashouri, Jinoos Yazdany, Gabriela Schmajuk

Publikováno v: BMC Medical Informatics and Decision Making, Vol 24, Iss 1, Pp 1-11 (2024)

Abstract Background Improving shared decision-making using a treat-to-target approach, including the use of clinical outcome measures, is important to providing high quality care for rheumatoid arthritis (RA). We developed an Electronic Health Record

Externí odkaz: https://doaj.org/article/a5af2647788e471483ba63a780c649d6

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Akademický článek

Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)

The oncoprotein c-Myc is often overexpressed in triple negative breast cancer and has a role in tumor progression and resistance to therapy. Here the authors show that elevated MYC expression is correlated with low immune infiltration, diminished MHC

Externí odkaz: https://doaj.org/article/5ba305a5a1f9497c9247af3f00c75bef

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Akademický článek

A simple point-of-care assay accurately detects anti-spike antibodies after SARS-CoV-2 vaccination

Autor: Sarah E. Greene, Yuefang Huang, Wooseob Kim, Mariel J. Liebeskind, Vinay Chandrasekaran, Zhuoming Liu, Parakkal Deepak, Michael A. Paley, Daphne Lew, Monica Yang, Mehrdad Matloubian, Lianne S. Gensler, Mary C. Nakamura, Jane A. O'Hallaran, Rachel M. Presti, Sean P.J. Whelan, William J. Buchser, Alfred H.J. Kim, Gary J. Weil

Publikováno v: Journal of Clinical Virology Plus, Vol 3, Iss 1, Pp 100135- (2023)

Objective: Lateral flow assays (LFA) are sensitive for detecting antibodies to SARS-CoV-2 proteins within weeks after infection. This study tested samples from immunocompetent adults, and those receiving treatments for chronic inflammatory diseases (

Externí odkaz: https://doaj.org/article/b66e64cea7a54f1a8f541b5f7c3ad1eb

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Akademický článek

Combined Single Cell Transcriptome and Surface Epitope Profiling Identifies Potential Biomarkers of Psoriatic Arthritis and Facilitates Diagnosis via Machine Learning

Autor: Jared Liu, Sugandh Kumar, Julie Hong, Zhi-Ming Huang, Diana Paez, Maria Castillo, Maria Calvo, Hsin-Wen Chang, Daniel D. Cummins, Mimi Chung, Samuel Yeroushalmi, Erin Bartholomew, Marwa Hakimi, Chun Jimmie Ye, Tina Bhutani, Mehrdad Matloubian, Lianne S. Gensler, Wilson Liao

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Early diagnosis of psoriatic arthritis (PSA) is important for successful therapeutic intervention but currently remains challenging due, in part, to the scarcity of non-invasive biomarkers. In this study, we performed single cell profiling of transcr

Externí odkaz: https://doaj.org/article/434161d42b6749f3aff3bfd04adb92e7

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Akademický článek

Perivascular Fibroblasts of the Developing Spleen Act as LTα1β2-Dependent Precursors of Both T and B Zone Organizer Cells

Autor: Karin Schaeuble, Mirjam R. Britschgi, Leo Scarpellino, Stéphanie Favre, Ying Xu, Ekaterina Koroleva, Tonje K.A. Lissandrin, Alexander Link, Mehrdad Matloubian, Carl F. Ware, Sergei A. Nedospasov, Alexei V. Tumanov, Jason G. Cyster, Sanjiv A. Luther

Publikováno v: Cell Reports, Vol 21, Iss 9, Pp 2500-2514 (2017)

T and B cell compartmentalization is a hallmark of secondary lymphoid organs and is maintained by chemokine-expressing stromal cells. How this stromal cell network initially develops and differentiates into two distinct subsets is poorly known, espec

Externí odkaz: https://doaj.org/article/c4368ff68f7f4f298c214ee6b02b6515

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Akademický článek

miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival

Publikováno v: Cell Reports, Vol 28, Iss 8, Pp 2169-2181.e4 (2019)

Summary: Coordinate control of T cell proliferation, survival, and differentiation are essential for host protection from pathogens and cancer. Long-lived memory cells, whose precursors are formed during the initial immunological insult, provide prot

Externí odkaz: https://doaj.org/article/a486a73611da46498ae2a935b948d107

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