Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Mehrdad Khajavi"'
Autor:
Mehrdad Khajavi, Yi Zhou, Amy E Birsner, Lauren Bazinet, Amanda Rosa Di Sant, Alex J Schiffer, Michael S Rogers, Subrahmanian Tarakkad Krishnaji, Bella Hu, Vy Nguyen, Leonard Zon, Robert J D'Amato
Publikováno v:
PLoS Genetics, Vol 13, Iss 6, p e1006848 (2017)
Recent findings indicate that growth factor-driven angiogenesis is markedly influenced by genetic variation. This variation in angiogenic responsiveness may alter the susceptibility to a number of angiogenesis-dependent diseases. Here, we utilized th
Externí odkaz:
https://doaj.org/article/ba60a7546ddf43369a605e6c840ee0ac
Autor:
Anthony Antonellis, Megan Y Dennis, Grzegorz Burzynski, Jimmy Huynh, Valerie Maduro, Chani J Hodonsky, Mehrdad Khajavi, Kinga Szigeti, Sandeep Mukkamala, Seneca L Bessling, William J Pavan, Andrew S McCallion, James R Lupski, Eric D Green, NISC Comparative Sequencing Program
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14346 (2010)
Myelin protein zero (MPZ) is a critical structural component of myelin in the peripheral nervous system. The MPZ gene is regulated, in part, by the transcription factors SOX10 and EGR2. Mutations in MPZ, SOX10, and EGR2 have been implicated in demyel
Externí odkaz:
https://doaj.org/article/0911ef5b476045b4ab4871b2f20a088a
Autor:
John V. Heymach, Randa El-Zein, Bernhard Riedel, Robert Schier, Amado Zurita, Li Xu, Andrea Cortes, Hua Kang Wu, Tina Cascone, Zhiqiang Du, Mehrdad Khajavi, Monique Nilsson, Reza Mehran
PDF file - 104KB, Quantitative analysis of CTEC and CEC/CEP populations in mouse specimens by flow cytometry. Syto16 (DNA) gate used to exclude apoptotic, necrotic debris and cellular degraded fragments. CECs were characterized as CD31+CD45-VEGFR-2+C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b73a754888d05cc8a2fba58cd31182
https://doi.org/10.1158/0008-5472.22398968
https://doi.org/10.1158/0008-5472.22398968
Autor:
John V. Heymach, Randa El-Zein, Bernhard Riedel, Robert Schier, Amado Zurita, Li Xu, Andrea Cortes, Hua Kang Wu, Tina Cascone, Zhiqiang Du, Mehrdad Khajavi, Monique Nilsson, Reza Mehran
PDF file - 40KB, CECs and CEPs in peripheral blood of normal and tumor-bearing mice were evaluated using flow cytometry. CTECs were first identified based on the staining pattern of CECs and further characterized using CD276 and TEM7 antibodies. (A)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e0c0e43e7b47e00b0ee620d215fbed2
https://doi.org/10.1158/0008-5472.22398962.v1
https://doi.org/10.1158/0008-5472.22398962.v1
Autor:
John V. Heymach, Randa El-Zein, Bernhard Riedel, Robert Schier, Amado Zurita, Li Xu, Andrea Cortes, Hua Kang Wu, Tina Cascone, Zhiqiang Du, Mehrdad Khajavi, Monique Nilsson, Reza Mehran
PDF file - 59KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba67b3a81751cc2878fa11c8bb721ee
https://doi.org/10.1158/0008-5472.22398959.v1
https://doi.org/10.1158/0008-5472.22398959.v1
Autor:
John V. Heymach, Randa El-Zein, Bernhard Riedel, Robert Schier, Amado Zurita, Li Xu, Andrea Cortes, Hua Kang Wu, Tina Cascone, Zhiqiang Du, Mehrdad Khajavi, Monique Nilsson, Reza Mehran
PDF file - 86KB, Quantitative analysis of CTEC and CEC/CEP populations in human specimens by eight-color flow cytometry. A, Syto16 (DNA) gate used to exclude apoptotic, necrotic debris and cellular degraded fragments. Syto16-positive cells (red and b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::217a1521205b8129ea61cada0966e3f4
https://doi.org/10.1158/0008-5472.22398965.v1
https://doi.org/10.1158/0008-5472.22398965.v1
Angiogenic responses in a 3D micro-engineered environment of primary endothelial cells and pericytes
Autor:
Jing Bai, Lauren Bazinet, Lufei Sui, Roger D. Kamm, Mehrdad Khajavi, Amy E. Birsner, Haojie Fu, Robert J. D'Amato, Subrahmanian Tarakkad Krishnaji
Publikováno v:
Springer Netherlands
Angiogenesis plays a key role in the pathology of diseases such as cancer, diabetic retinopathy, and age-related macular degeneration. Understanding the driving forces of endothelial cell migration and organization, as well as the time frame of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f2c077c70f5553022a4764bef2d78b9
https://doi.org/10.1007/s10456-020-09746-6
https://doi.org/10.1007/s10456-020-09746-6
Autor:
Lauren Bazinet, Yi Zhou, Amy E. Birsner, Robert J. D'Amato, Leonard I. Zon, Mehrdad Khajavi, Alex J. Schiffer
Publikováno v:
FASEB J
We have previously used the genetic diversity available in common inbred mouse strains to identify quantitative trait loci (QTLs) responsible for the differences in angiogenic response using the corneal micropocket neovascularization (CoNV) assay. Em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ebfe57997248164b89a25697cd2835
https://doi.org/10.1096/fj.202001936rrr
https://doi.org/10.1096/fj.202001936rrr
Autor:
Ofra Benny, Ouri Schwob, Miriam Maoz, Dvir Dror, Adi Inbal, Rawnaq Esa, Aviad Zick, Mehrdad Khajavi, Eliana Steinberg, Yael Kinarty
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 14
International Journal of Molecular Sciences, Vol 21, Iss 5148, p 5148 (2020)
Volume 21
Issue 14
International Journal of Molecular Sciences, Vol 21, Iss 5148, p 5148 (2020)
During the metastasis process, tumor cells invade the blood circulatory system directly from venous capillaries or indirectly via lymphatic vessels. Understanding the relative contribution of each pathway and identifying the molecular targets that af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee4ecdf62886d6528cb8fec366f1677
http://europepmc.org/articles/PMC7403956
http://europepmc.org/articles/PMC7403956
Autor:
Mehrdad Khajavi, John V. Heymach, Samuel E. DePrimo, William Carley, Matthew H. Kulke, Heinz-Josef Lenz, Xin-Yun Huang, E. Lin, Hua-Kang Wu, Amado J. Zurita, Charles S. Harmon, Neal J. Meropol, X. Wang, L. Tye
Publikováno v:
British Journal of Cancer
Background: Sunitinib is approved worldwide for treatment of advanced pancreatic neuroendocrine tumours (pNET), but no validated markers exist to predict response. This analysis explored biomarkers associated with sunitinib activity and clinical bene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab861164abb78946d4c78ae1a0320881
https://doi.org/10.1038/bjc.2015.73
https://doi.org/10.1038/bjc.2015.73