Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mehmet Zeynel Cilek"'
Autor:
Mehmet Zeynel Cilek, Kazuo Kaneko, Muneaki Ishijima, Yasunori Okada, Satsuki Mochizuki, Miyuki Chijiiwa, Susana de Vega, J. Shiozawa, Chiho Yoshinaga, Yuka Miyamae, Haruka Kaneko, Masatoshi Ito
Publikováno v:
Laboratory Investigation. 102:102-111
The ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family includes nine members with aggrecan-degrading activity, i.e., ADAMTS1, 4, 5, 8, 9, 15, 16, 18, and 20. However, their systematic expression profile in knee osteoarthri
Autor:
Tomomi Nakamura, Chiho Yoshinaga, Yasunori Okada, Mehmet Zeynel Cilek, Muneaki Ishijima, Haruka Kaneko, Susana de Vega, Hiroyuki Yoshida, Kazuo Kaneko, Shinya Kasamatsu, J. Shiozawa
Publikováno v:
The American Journal of Pathology. 190:1046-1058
Cell migration-inducing hyaluronidase 1 (CEMIP), also known as hyaluronan (HA)-binding protein involved in HA depolymerization (HYBID), plays a role in HA degradation. CEMIP2, also known as transmembrane protein 2 (TMEM2), possessing a sequence simil
Autor:
Mehmet Zeynel, Cilek, Susana, de Vega, Jun, Shiozawa, Chiho, Yoshinaga, Yuka, Miyamae, Miyuki, Chijiiwa, Satsuki, Mochizuki, Masatoshi, Ito, Haruka, Kaneko, Kazuo, Kaneko, Muneaki, Ishijima, Yasunori, Okada
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 102(1)
The ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family includes nine members with aggrecan-degrading activity, i.e., ADAMTS1, 4, 5, 8, 9, 15, 16, 18, and 20. However, their systematic expression profile in knee osteoarthri
Autor:
Akira Shinaoka, Toshitaka Oohashi, Mehmet Zeynel Cilek, Satoshi Hirohata, Omer Faruk Hatipoglu, Keiichiro Nishida, Keiichi Asano, Kanae Kumagishi-Shinaoka, Junko Inagaki, Issei Komatsubara, Takashi Ohtsuki
Publikováno v:
Journal of Orthopaedic Research®. 36:3247-3255
Hyaluronan (HA) is an extracellular matrix (ECM) component of articular cartilage and has been used to treat patients with osteoarthritis (OA). A disintegrin and metalloproteinases with thrombospondin motifs (ADAMTSs) play an important role in cartil
Autor:
Yasunori Okada, Mika Aoki, Tetsuya Sayo, Yoshito Takahashi, Hiroyuki Yoshida, Mehmet Zeynel Cilek, Kohei Yamazaki, Shinya Kasamatsu, Aya Komiya, T. Murata
Publikováno v:
International journal of cosmetic science. 41(1)
Hyaluronan (HA), an important constituent of extracellular matrix in the skin, has many biological activities such as hydration that contributes to firmness and bounciness of the skin. We have reported that reduction in HA in the papillary dermis and
Autor:
M. Ito, Kazuo Kaneko, Yuka Miyamae, Yohei Okada, J. Shiozawa, Satsuki Mochizuki, Haruka Kaneko, Muneaki Ishijima, S. de Vega, Mehmet Zeynel Cilek
Publikováno v:
Osteoarthritis and Cartilage. 27:S196
Autor:
Mehmet Zeynel Cilek, Toru Miyoshi, Shozo Kusachi, Takashi Ohtsuki, Satoshi Hirohata, Hiroshi Harada, Omer Faruk Hatipoglu, Hiroko Ogawa, Shigeshi Kamikawa, Junko Inagaki, Yoshifumi Ninomiya
Publikováno v:
Cell Biology International. 35:1-8
ADAMTS1 (a disintegrin and metalloproteinase with thrombospondin motifs 1) is an early immediate gene. We have previously reported that ADAMTS1 was strongly induced by hypoxia. In this study, we investigated whether ADAMTS1 promoter-driven reporter s
Autor:
Noboru Yamanaka, Mehmet Gunduz, Yoshifumi Ninomiya, Levent Bekir Beder, Kenji Shimizu, Hitoshi Nagatsuka, Beyhan Cengiz, Satoshi Hirohata, Mehmet Zeynel Cilek, Esra Gunduz, Kadir Demircan
Publikováno v:
Head & Neck. 31:793-801
Background. Although contribution of matrix metalloproteinases in cancer progression and dissemination is now well known, roles of recently discovered metalloproteinases, a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS), in can
Autor:
Mahmoud A L Sheikh Ali, Hitoshi Nagatsuka, Silvia Susana Borkosky, Mehmet Gunduz, Levent Bekir Beder, Mehmet Zeynel Cilek, Esra Gunduz, Susumu Tominaga, Kenji Shimizu, Noboru Yamanaka, Noriyuki Nagai, Andrea Paola Rodriguez
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 135:703-713
Loss of heterozygosity (LOH) in the ING family members has been shown in head and neck squamous cell carcinoma (HNSCC) except for ING2. Like all the other members of ING family, ING2, which is located at chromosome 4q35.1, is a promising tumor suppre
Autor:
Mehmet Zeynel Cilek, Takashi Ohtsuki, Shozo Kusachi, Masanari Obika, Satoshi Hirohata, Junko Inagaki, Matthias Hofmann, Keiichi Asano, Omer Faruk Hatipoglu, Hiroko Ogawa, Katsuyuki Takahashi, Yoshifumi Ninomiya
Publikováno v:
Experimental cell research. 323(2)
Angiogenesis and lymphangiogenesis play roles in malignant tumor progression, dissemination, and metastasis. ADAMTS1, a member of the matrix metalloproteinase family, is known to inhibit angiogenesis. Recombinant ADAMTS1 was shown to strongly inhibit