Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Mehmet O. Kilinc"'
Supplementary Figure 1 from Central Role of IFNγ–Indoleamine 2,3-Dioxygenase Axis in Regulation of Interleukin-12–Mediated Antitumor Immunity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3874968bcc57ef289ed4aeecd395251
https://doi.org/10.1158/0008-5472.22382061
https://doi.org/10.1158/0008-5472.22382061
Supplementary Figure 2 from Central Role of IFNγ–Indoleamine 2,3-Dioxygenase Axis in Regulation of Interleukin-12–Mediated Antitumor Immunity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37444b235c887b2873e73cfb2472302
https://doi.org/10.1158/0008-5472.22382058
https://doi.org/10.1158/0008-5472.22382058
Supplementary Figure 3 from Central Role of IFNγ–Indoleamine 2,3-Dioxygenase Axis in Regulation of Interleukin-12–Mediated Antitumor Immunity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d95dfc986ae3f600d63cd2e2ff3e53c
https://doi.org/10.1158/0008-5472.22382055.v1
https://doi.org/10.1158/0008-5472.22382055.v1
Sustained intratumoral delivery of interleukin-12 (IL-12) and granulocyte macrophage colony-stimulating factor induces tumor regression via restoration of tumor-resident CD8+ T-effector/memory cell cytotoxicity and subsequent repriming of a secondary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9c7085eb54f328e4720ad78bf850685
https://doi.org/10.1158/0008-5472.c.6500082.v1
https://doi.org/10.1158/0008-5472.c.6500082.v1
Autor:
Dobrin Draganov, Elliot B Lander, Ivelina Minev, Ivan Petrov, Antonio F. Santidrian, Duong Nguyen, Boris Minev, Aladar A. Szalay, Mehmet O. Kilinc, Mark Berman, Anna Vyalkova
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb470224cbaa9b2a826cc87175099eba
https://doi.org/10.1186/s12967-021-02866-7
https://doi.org/10.1186/s12967-021-02866-7
Autor:
Mark Berman, Antonio F. Santidrian, Aladar A. Szalay, Duong Nguyen, Ivelina Minev, Mehmet O. Kilinc, Elliot B Lander, Boris Minev, Ivan Petrov, Dobrin Draganov, Anna Vyalkova
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-22 (2019)
Journal of Translational Medicine
Journal of Translational Medicine
Background Previous studies have identified IFNγ as an important early barrier to oncolytic viruses including vaccinia. The existing innate and adaptive immune barriers restricting oncolytic virotherapy, however, can be overcome using autologous or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e5b3ee66e5f9e19568a5de89c1389a
http://link.springer.com/article/10.1186/s12967-019-1829-z
http://link.springer.com/article/10.1186/s12967-019-1829-z
Autor:
Duong Nguyen, Mark Berman, Mehmet O. Kilinc, Boris Minev, Robert Toth, Elliot B Lander, Aladar A. Szalay, Ivelina Minev, Antonio F. Santidrian, Dobrin Draganov
Publikováno v:
Clinical and Translational Medicine, Vol 7, Iss 1, Pp 1-20 (2018)
Clinical and Translational Medicine
Clinical and Translational Medicine
Background Stromal vascular fraction (SVF) represents an attractive source of adult stem cells and progenitors, holding great promise for numerous cell therapy approaches. In 2017, it was reported that 1524 patients received autologous SVF following
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6471cbd148adae19e321ec2a42dffad
http://link.springer.com/article/10.1186/s40169-018-0183-8
http://link.springer.com/article/10.1186/s40169-018-0183-8
Autor:
Nejat K. Egilmez, Mehmet O. Kilinc
Publikováno v:
Archivum Immunologiae et Therapiae Experimentalis. 58:399-405
Tumor-resident T cells display a functionally impaired effector/memory (Tem) phenotype. Sustained intratumoral administration of IL-12, on the other hand, can restore cytolytic function to pre-existing CD8+ Tem, resulting in effective tumor kill. Whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c02267bd06b60fb6b87d0cbf9b1b02
https://doi.org/10.1007/s00005-010-0097-7
https://doi.org/10.1007/s00005-010-0097-7
Publikováno v:
Cancer Research. 70:129-138
Sustained intratumoral delivery of interleukin-12 (IL-12) and granulocyte macrophage colony-stimulating factor induces tumor regression via restoration of tumor-resident CD8+ T-effector/memory cell cytotoxicity and subsequent repriming of a secondary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::679f9687a6b69e483ea9141cd089d663
https://doi.org/10.1158/0008-5472.can-09-3170
https://doi.org/10.1158/0008-5472.can-09-3170
Publikováno v:
The Journal of Immunology. 183:7656-7660
Tumor-resident CD8+ T cells display a quiescent effector/memory phenotype that is maintained in part by infiltrating CD4+ CD25+ Foxp3+ T-suppressor cells. Intratumoral delivery of IL-12, in contrast, can restore cytotoxic function to tumor-associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4d213bdc154ffbd6eb9b1463e20611
https://doi.org/10.4049/jimmunol.0902625
https://doi.org/10.4049/jimmunol.0902625