Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Mehdi Valipour"'
Autor:
Mehdi Valipour, Zahra Zakeri, Kaveh Kiadaliry, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Mohammad Shokati Sayyad, Mohammad Seyedabadi, Majid Ghasemian, Seyedeh Mahdieh Hashemi, Hamid Irannejad
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 12, Iss , Pp 100207- (2024)
Type 2 diabetes is a common condition that causes the level of glucose in the blood to become too high and α-glucosidase inhibitors are therapeutic agents in managing type 2 diabetes. In the present study, we report a new series of 3-aceto(benzo)hyd
Externí odkaz:
https://doaj.org/article/3a15142535f74b009bfc0fa2c9c502f6
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2619 (2023)
Ongoing viral research, essential for public health due to evolving viruses, gains significance owing to emerging viral infections such as the SARS-CoV-2 pandemic. Marine and plant alkaloids show promise as novel potential pharmacological strategies.
Externí odkaz:
https://doaj.org/article/8f20a29974944b8b92f975d3654b8edb
Publikováno v:
Journal of Mazandaran University of Medical Sciences, Vol 31, Iss 201, Pp 192-212 (2021)
Background and purpose: Liver is a vital organ in the body that plays key roles in metabolism and secreting enzymes. A better understanding of this vital organ for better care has always been of interest to researchers. Carbon tetrachloride (CCl4) is
Externí odkaz:
https://doaj.org/article/c54f9703a585463abad4be52b0038576
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8789 (2023)
Previous studies indicated that natural-based chalcones have significant inhibitory effects on the coronavirus enzymes 3CLpro and PLpro as well as modulation of some host-based antiviral targets (HBATs). In this study, a comprehensive computational a
Externí odkaz:
https://doaj.org/article/b59aeb6a86644944bcf644a5026de0a1
Autor:
Mehdi Valipour, Hamid Irannejad
Publikováno v:
Journal of Mazandaran University of Medical Sciences, Vol 29, Iss 172, Pp 188-206 (2019)
Epilepsy is a neurological condition characterized by recurrent seizures influencing about 1% of the worldwide population. Despite much progress in understanding the pathogenesis of epilepsy, the molecular basis of human epilepsy still remains unclea
Externí odkaz:
https://doaj.org/article/df433be6273849faaddff7fa2ba1a75a
Publikováno v:
Phytotherapy Research. 37:2168-2186
Publikováno v:
Cell cycle (Georgetown, Tex.). 21(22)
Emetine is one of the most highly potent anti-SARS-CoV-2 agents ever identified. In addition to having strong anti-SARS-CoV-2 activities, emetine has other valuable therapeutic effects such as strong anti-inflammatory and anti-arterial pulmonary hype
Autor:
Mehdi Valipour
Publikováno v:
Phytotherapy Research. 36:4477-4490
Chalcone is an interesting scaffold found in the structure of many naturally occurring molecules. Medicinal chemists are commonly interested in designing new chalcone-based structures because of having the α, β-unsaturated ketone functional group,
Publikováno v:
Letters in Drug Design & Discovery. 20
background: Shikonin and alkannin derivatives have various pharmacological activities with unknown mechanisms of action. Sirtuins are key intracellular enzymes involved in the cell cycle and metabolism and are ideal targets of therapeutic agents. The
Publikováno v:
Cell Cycle
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Multifunctional nature of phytochemicals and their chemical diversity has attracted attention to develop leads originated from nature to fight COVID-19. Pharmacological activities of chelerythrine and its congeners have been studied and reported in t