Výsledky vyhledávání - "Mehdi Sabzichi"

Akademický článek

Sphingosine 1-phosphate interacts with Survivin pathway to enhance tumorigenesis in cancer cells

Autor: Maryam Tabasinezhad, Hamid Ghaedi, Parisa Qanbari, Mahsa Mohseni, Mehdi Sabzichi, Nasser Samadi

Publikováno v: Iranian Journal of Basic Medical Sciences, Vol 18, Iss 8, Pp 813-821 (2015)

Objective(s):Degradation of sphingosine 1-phosphate (S1P), as a bioactive lipid, or deregulation of its production involves in tumor progression, metastasis and chemoresistance. Since the tumor progression effects of S1P and its mechanism in chronic

Externí odkaz: https://doaj.org/article/fe200351c52f4e31b77a23047f00e164

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Zoledronic acid-loaded lipidic nanoparticles enhance apoptosis and attenuate invasiveness by inhibiting epithelial to mesenchymal transition (EMT) in HepG2 cancer cells

Autor: Marjan Ghorbani, Alireza Mardomi, Mohsen Rashidi, Mahla Hosseinzadeh, Mehdi Sabzichi, Omolbanin Oladpour, Jamal Mohammadian, Fatemeh Ramezani, Bahman Ramezani

Publikováno v: Naunyn-Schmiedeberg's Archives of Pharmacology. 394:2429-2439

The aim of this study was to evaluate the potential of zoledronic acid (ZOL)-loaded lipidic nanoparticles (ZOL-NLCs) in enhancing the efficiency of paclitaxel (Pac) in the context of cytotoxicity, apoptosis, and invasiveness of HepG2 hepatocellular c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c0155c0abe62a1c2a3f05b03601a678
https://doi.org/10.1007/s00210-021-02164-5

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Blockade of TGF-βR improves the efficacy of doxorubicin by modulating the tumor cell motility and affecting the immune cells in a melanoma model

Autor: Mahsa Panahi, Mohsen Korani, Mohammad Parsa-Kondelaji, Alireza Mardomi, Mehdi Sabzichi, Ali Salimi, Marzieh Ghollasi

Publikováno v: Naunyn-Schmiedeberg's Archives of Pharmacology. 394:2309-2322

TGF-β contributes to drug resistance and the invasiveness of tumor cells and weakens the anti-tumor immune responses. The present study aimed at examining the efficacy of the combination of SB431542, as a specific inhibitor of TGF-βR, and doxorubic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7355742ef1ecf8bed33ad1d9921895bc
https://doi.org/10.1007/s00210-021-02134-x

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Sensitization of A-549 lung cancer cells to Cisplatin by Quinacrine-loaded lipidic nanoparticles via suppressing Nrf2 mediated defense mechanism

Autor: Mohammadbagher Pirouzpanah, Mehdi Sabzichi, Mostafa Mohammadi, Shiva Mahmoudi, Marjan Ghorbani, Hossain Bijanpour, Jamal Mohammadian, Mohsen Rashidi, Fatemeh Ramezani, Shahram Ahmadian, Nazila Fathi Maroufi

Publikováno v: Naunyn-Schmiedeberg's Archives of Pharmacology. 394:1521-1528

Nuclear factor erythroid 2-related factor 2 (Nrf2) is believed to be responsible for the control mechanisms of cellular defense response and master regulator of antioxidant system by adjustment of endogenous antioxidants, phase II detoxifying enzymes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91294c2b2676c8cad9746b1c1301f1b8
https://doi.org/10.1007/s00210-021-02079-1

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Harnessing WYE-132 as an inhibitor of the mTOR signaling enriches the cytotoxicity effect of vinblastine in B16F10 melanoma cancer cells

Autor: Bahman Ramezani, Hamed Hamishehkar, Mehdi Sabzichi, Jamal Mohammadian, Fatemeh Khaki-Khatibi, Mahdi Zeinali

Publikováno v: Process Biochemistry. 99:123-130

This study aimed to evaluate the synergistic anticancer effect of vinblastine and WYE-132, a specific inhibitor of the mammalian target of rapamycin (mTOR), on B16F10 melanoma cancer cells. MTT assay, Annexin V, and DAPI staining along with Real-Time

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1d77edf8a6402027350425d8dc93f7e9
https://doi.org/10.1016/j.procbio.2020.08.026

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Formulation of Stattic as STAT3 inhibitor in nanostructured lipid carriers (NLCs) enhances efficacy of doxorubicin in melanoma cancer cells

Autor: Shiva Mahmoudi, Nazila Fathi Maroufi, Fatemeh Salehnia, Mehdi Sabzichi, Nasser Samadi, Pirouz Pourmohammad, Mohammad Bagher Pirouzpanah, Jamal Mohammadian

Publikováno v: Naunyn-Schmiedeberg's Archives of Pharmacology. 393:2315-2323

Nowadays, nanoparticle-based combination therapy has been emerging as huge innovation in cancer treatment. Here, we studied the effect of Stattic (STAT3 inhibitor) loaded in nanostructured lipid carriers (NLCs) on enhancing the efficacy, cytotoxicity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9cffacac4b14f46b0f8be6a419ea741
https://doi.org/10.1007/s00210-020-01942-x

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