Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Mehdi Masoomian"'
Autor:
Joseph Longo, Peter J. Mullen, Rosemary Yu, Jenna E. van Leeuwen, Mehdi Masoomian, Dixon T.S. Woon, Yuzhuo Wang, Eric X. Chen, Robert J. Hamilton, Joan M. Sweet, Theodorus H. van der Kwast, Neil E. Fleshner, Linda Z. Penn
Publikováno v:
Molecular Metabolism, Vol 25, Iss , Pp 119-130 (2019)
Objective: The statin family of cholesterol-lowering drugs has been shown to induce tumor-specific apoptosis by inhibiting the rate-limiting enzyme of the mevalonate (MVA) pathway, HMG-CoA reductase (HMGCR). Accumulating evidence suggests that statin
Externí odkaz:
https://doaj.org/article/f03d8eaff63e4e4990bc23cc62eb3734
Publikováno v:
Journal of Family and Reproductive Health, Vol 2, Iss 3 (2008)
Tuberculosis (TB) is the most common infectious cause of human death. After the lung, genitourinary tract is the most common site for TB infection. Pelvic tuberculosis should be considered in young women presented with pelvic mass, ascites, fever, an
Externí odkaz:
https://doaj.org/article/f0a5950d83dd45e99223bf803d733129
Autor:
George Zogopoulos, Steven Gallinger, Jennifer J. Knox, Sandra E. Fischer, Grainne M. O'Kane, Talia Golan, William D. Foulkes, Paz Polak, Celia M.T. Greenwood, James Biagi, David Valenti, Louis-Martin Boucher, Tatiana Cabrera, Nathaniel Bouganim, Jamil Asselah, Yasser Riazalhosseini, Zu-Hua Gao, Julie M. Wilson, John M.S. Bartlett, Ilinca M. Lungu, Mehdi Masoomian, Simeng Bu, Chani Stossel, Spring Holter, Ayelet Borgida, Robert C. Grant, Maria Raitses-Gurevich, Jean Monlong, Celine Domecq, Adeline Cuggia, Amy Zhang, Gun Ho Jang, Robert E. Denroche, Alain Pacis, Jin Yong Patrick Park, Yifan Wang
Supplementary Figure 1 shows the results of the Disambiguate algorithm used to assign the PDAC xenograft RNAseq reads to individual species
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2551ac02968df13e31c3e40f57529427
https://doi.org/10.1158/1078-0432.22476474
https://doi.org/10.1158/1078-0432.22476474
Autor:
Steven Gallinger, George Zogopoulos, Yifan Wang, Ashton Connor, Jennifer J. Knox, Julie M. Wilson, Grainne M. O'Kane, Susan J. Done, Pamela S. Ohashi, Faiyaz Notta, Tracy L. McGaha, Rama Khokha, Peter Bronsert, Foram Vyas, Dianne Chadwick, Sheng-Ben Liang, Sharon Dhaliwal, Niandong Li, Jing Xu, John M.S. Bartlett, Angela De Luca, Ilinca M. Lungu, Robert E. Denroche, Amy Zhang, Sandra E. Fischer, Mehdi Masoomian, Aaditeya Jhaveri, Prashant P. Bavi, Gun-Ho Jang, Barbara Grünwald, Joan M. Romero
Supplementary Figure 3: Association of chemokine expression with a T cell-inflamed phenotype was validated in a second independent PDAC patient cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c2148a577fe64176830f0b01dcfd519
https://doi.org/10.1158/1078-0432.22477580
https://doi.org/10.1158/1078-0432.22477580
Autor:
George Zogopoulos, Steven Gallinger, Jennifer J. Knox, Sandra E. Fischer, Grainne M. O'Kane, Talia Golan, William D. Foulkes, Paz Polak, Celia M.T. Greenwood, James Biagi, David Valenti, Louis-Martin Boucher, Tatiana Cabrera, Nathaniel Bouganim, Jamil Asselah, Yasser Riazalhosseini, Zu-Hua Gao, Julie M. Wilson, John M.S. Bartlett, Ilinca M. Lungu, Mehdi Masoomian, Simeng Bu, Chani Stossel, Spring Holter, Ayelet Borgida, Robert C. Grant, Maria Raitses-Gurevich, Jean Monlong, Celine Domecq, Adeline Cuggia, Amy Zhang, Gun Ho Jang, Robert E. Denroche, Alain Pacis, Jin Yong Patrick Park, Yifan Wang
Supplementary Figure 9 shows the Cox proportional hazards model, integrating Moffitt transcriptomic subtype, tumour ploidy, stage and age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027feb79416c28565c2b063c69ff94c5
https://doi.org/10.1158/1078-0432.22476441.v1
https://doi.org/10.1158/1078-0432.22476441.v1
Autor:
Steven Gallinger, George Zogopoulos, Yifan Wang, Ashton Connor, Jennifer J. Knox, Julie M. Wilson, Grainne M. O'Kane, Susan J. Done, Pamela S. Ohashi, Faiyaz Notta, Tracy L. McGaha, Rama Khokha, Peter Bronsert, Foram Vyas, Dianne Chadwick, Sheng-Ben Liang, Sharon Dhaliwal, Niandong Li, Jing Xu, John M.S. Bartlett, Angela De Luca, Ilinca M. Lungu, Robert E. Denroche, Amy Zhang, Sandra E. Fischer, Mehdi Masoomian, Aaditeya Jhaveri, Prashant P. Bavi, Gun-Ho Jang, Barbara Grünwald, Joan M. Romero
Supplementary Table 1: Top 99 genes associating with CD8+ TIL counts in primary resected cases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9ad799ac3e5f88e9b54d93aa5a0fd99
https://doi.org/10.1158/1078-0432.22477568.v1
https://doi.org/10.1158/1078-0432.22477568.v1
Autor:
George Zogopoulos, Steven Gallinger, Jennifer J. Knox, Sandra E. Fischer, Grainne M. O'Kane, Talia Golan, William D. Foulkes, Paz Polak, Celia M.T. Greenwood, James Biagi, David Valenti, Louis-Martin Boucher, Tatiana Cabrera, Nathaniel Bouganim, Jamil Asselah, Yasser Riazalhosseini, Zu-Hua Gao, Julie M. Wilson, John M.S. Bartlett, Ilinca M. Lungu, Mehdi Masoomian, Simeng Bu, Chani Stossel, Spring Holter, Ayelet Borgida, Robert C. Grant, Maria Raitses-Gurevich, Jean Monlong, Celine Domecq, Adeline Cuggia, Amy Zhang, Gun Ho Jang, Robert E. Denroche, Alain Pacis, Jin Yong Patrick Park, Yifan Wang
Supplementary Figure 5 shows the immunohistochemical analysis of apoptotic activity in xenografts treated with gemcitabine mono- and combination therapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197507ab9b4c49f538d54d071829146c
https://doi.org/10.1158/1078-0432.22476456.v1
https://doi.org/10.1158/1078-0432.22476456.v1
Autor:
George Zogopoulos, Steven Gallinger, Jennifer J. Knox, Sandra E. Fischer, Grainne M. O'Kane, Talia Golan, William D. Foulkes, Paz Polak, Celia M.T. Greenwood, James Biagi, David Valenti, Louis-Martin Boucher, Tatiana Cabrera, Nathaniel Bouganim, Jamil Asselah, Yasser Riazalhosseini, Zu-Hua Gao, Julie M. Wilson, John M.S. Bartlett, Ilinca M. Lungu, Mehdi Masoomian, Simeng Bu, Chani Stossel, Spring Holter, Ayelet Borgida, Robert C. Grant, Maria Raitses-Gurevich, Jean Monlong, Celine Domecq, Adeline Cuggia, Amy Zhang, Gun Ho Jang, Robert E. Denroche, Alain Pacis, Jin Yong Patrick Park, Yifan Wang
Supplementary Figure 7 shows the comparison of COSMIC SBS mutational signatures between untreated parent xenografts vs. xenografts treated with gemcitabine-cisplatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4195d070bec976a49c8d7035e042733
https://doi.org/10.1158/1078-0432.22476450.v1
https://doi.org/10.1158/1078-0432.22476450.v1
Autor:
George Zogopoulos, Steven Gallinger, Jennifer J. Knox, Sandra E. Fischer, Grainne M. O'Kane, Talia Golan, William D. Foulkes, Paz Polak, Celia M.T. Greenwood, James Biagi, David Valenti, Louis-Martin Boucher, Tatiana Cabrera, Nathaniel Bouganim, Jamil Asselah, Yasser Riazalhosseini, Zu-Hua Gao, Julie M. Wilson, John M.S. Bartlett, Ilinca M. Lungu, Mehdi Masoomian, Simeng Bu, Chani Stossel, Spring Holter, Ayelet Borgida, Robert C. Grant, Maria Raitses-Gurevich, Jean Monlong, Celine Domecq, Adeline Cuggia, Amy Zhang, Gun Ho Jang, Robert E. Denroche, Alain Pacis, Jin Yong Patrick Park, Yifan Wang
Supplementary Figure 3 shows the histological analysis of the xenografts evaluated in the preclinical trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856666aa84c679ca3fae5d8132682588
https://doi.org/10.1158/1078-0432.22476465.v1
https://doi.org/10.1158/1078-0432.22476465.v1
Autor:
George Zogopoulos, Steven Gallinger, Jennifer J. Knox, Sandra E. Fischer, Grainne M. O'Kane, Talia Golan, William D. Foulkes, Paz Polak, Celia M.T. Greenwood, James Biagi, David Valenti, Louis-Martin Boucher, Tatiana Cabrera, Nathaniel Bouganim, Jamil Asselah, Yasser Riazalhosseini, Zu-Hua Gao, Julie M. Wilson, John M.S. Bartlett, Ilinca M. Lungu, Mehdi Masoomian, Simeng Bu, Chani Stossel, Spring Holter, Ayelet Borgida, Robert C. Grant, Maria Raitses-Gurevich, Jean Monlong, Celine Domecq, Adeline Cuggia, Amy Zhang, Gun Ho Jang, Robert E. Denroche, Alain Pacis, Jin Yong Patrick Park, Yifan Wang
Supplementary Figure 6 shows the tumour ploidy analysis of xenografts evaluated in the preclinical trial that were not whole genome sequenced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05daacfc10d63a452d0b93bf46da3313
https://doi.org/10.1158/1078-0432.22476453
https://doi.org/10.1158/1078-0432.22476453