Výsledky vyhledávání - "Mehdi Hammadi"

Akademický článek

TRPM8 as an Anti–Tumoral Target in Prostate Cancer Growth and Metastasis Dissemination

Autor: Guillaume P. Grolez, Giorgia Chinigò, Alexandre Barras, Mehdi Hammadi, Lucile Noyer, Kateryna Kondratska, Etmar Bulk, Thibauld Oullier, Séverine Marionneau-Lambot, Marilyne Le Mée, Stéphanie Rétif, Stéphanie Lerondel, Antonino Bongiovanni, Tullio Genova, Sébastien Roger, Rabah Boukherroub, Albrecht Schwab, Alessandra Fiorio Pla, Dimitra Gkika

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 12, p 6672 (2022)

In the fight against prostate cancer (PCa), TRPM8 is one of the most promising clinical targets. Indeed, several studies have highlighted that TRPM8 involvement is key in PCa progression because of its impact on cell proliferation, viability, and mig

Externí odkaz: https://doaj.org/article/a1a35eee302a42869d7e8ffa8b73694b

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WDM and DWDM based RoF system in Fiber Optic Communication Systems: A review

Autor: Duhaq Ehasn Mohsen, Ali Mehdi Hammadi, Ali J. Al-Askery

Publikováno v: International Journal of Communication Networks and Information Security (IJCNIS). 13

The utilization of Fiber Optic (FO) in 5G communication systems has achieved several advantages such as increasing the capacity and the bit rate with a reduction in the total implementation cost. Radio over Fiber (RoF) systems could form the basis fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::969e8dcc0e8b643595ef6ef6ca1bf8ac
https://doi.org/10.17762/ijcnis.v13i1.4887

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Epigenetic dysregulation of KCa3.1 channels induces poor prognosis in lung cancer

Autor: Andreas H. Jacobs, Antje Hascher, Christian Rohde, Halima Ouadid-Ahidouch, Nils H. Thoennissen, Albrecht Schwab, Martin Dugas, Rainer Wiewrodt, Etmar Bulk, Carsten Müller-Tidow, Hans-Ulrich Klein, Mehdi Hammadi, Ludger Hillejan, Sonja Schelhaas, Wolfgang E. Berdel, Anne-Sophie Ay, Eva Schmidt, Alessandro Marra

Publikováno v: International Journal of Cancer. 137:1306-1317

Epigenomic changes are an important feature of malignant tumors. How tumor aggressiveness is affected by DNA methylation of specific loci is largely unexplored. In genome-wide DNA methylation analyses, we identified the KCa 3.1 channel gene (KCNN4) p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::33460bc116d425932b3fd32db60bb901
https://doi.org/10.1002/ijc.29490

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CD95-Mediated Calcium Signaling

Autor: Thomas Ducret, Anne-Marie Vacher, Pierre Vacher, Vanessa Delcroix, Mehdi Hammadi

Publikováno v: Methods in Molecular Biology ISBN: 9781493967780

Intracellular calcium signals regulate cell function and cell survival by controlling many processes. CD95 engagement results in distinct intracellular calcium signals that control the cell fate, apoptosis, or survival, depending on the ligand (membr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::43f83543249e621c1ac4783d22226575
https://doi.org/10.1007/978-1-4939-6780-3_8

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The apoptotic members CD95, BclxL, and Bcl-2 cooperate to promote cell migration by inducing Ca(2+) flux from the endoplasmic reticulum to mitochondria

Autor: Pierre Vacher, Marine Malleter, Yves Gouriou, Chi Li, L. Debure, Patrick Legembre, E. Lepvrier, Vanessa Delcroix, Amélie Fouqué, Mehdi Hammadi, Michel Ovize, Thomas Ducret

Publikováno v: Cell Death and Differentiation
Cell Death and Differentiation, Nature Publishing Group, 2016, 23 (10), pp.1702-1716. ⟨10.1038/cdd.2016.61⟩
Cell Death and Differentiation, 2016, 23 (10), pp.1702-1716. ⟨10.1038/cdd.2016.61⟩

International audience; Metalloprotease-processed CD95L (cl-CD95L) is a soluble cytokine that implements a PI3K/Ca 2+ signaling pathway in triple-negative breast cancer (TNBC) cells. Accordingly, high levels of cl-CD95L in TNBC women correlate with p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39cd4ba433ea04f7dd7ec841dc8ecc28
https://hal.archives-ouvertes.fr/hal-02378072/document

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The antidepressant fluoxetine induces necrosis by energy depletion and mitochondrial calcium overload

Autor: Thomas Ducret, Vanessa Delcroix, Paula Nunes, Mehdi Hammadi, Philippe Kischel, Emilie Charles, Anne-Marie Vacher, Anne Devin, Pierre Vacher, Cyril Castelbout, Nicolas Demaurex

Publikováno v: Oncotarget (2016)
Oncotarget
Oncotarget, 2017, 8 (2), pp.3181-3196. ⟨10.18632/oncotarget.13689⟩

International audience; Selective Serotonin Reuptake Inhibitor antidepressants, such as fluoxetine (Prozac), have been shown to induce cell death in cancer cells, paving the way for their potential use as cancer therapy. These compounds are able to i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82bca7cf49b3e2d938502b5e2e0571ce
https://archive-ouverte.unige.ch/unige:93334

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Epigenetic dysregulation of KCa 3.1 channels induces poor prognosis in lung cancer

Autor: Etmar, Bulk, Anne-Sophie, Ay, Mehdi, Hammadi, Halima, Ouadid-Ahidouch, Sonja, Schelhaas, Antje, Hascher, Christian, Rohde, Nils H, Thoennissen, Rainer, Wiewrodt, Eva, Schmidt, Alessandro, Marra, Ludger, Hillejan, Andreas H, Jacobs, Hans-Ulrich, Klein, Martin, Dugas, Wolfgang E, Berdel, Carsten, Müller-Tidow, Albrecht, Schwab

Publikováno v: International journal of cancer. 137(6)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4793200e5c6dd7de5f71dfb86748e4f7
https://pubmed.ncbi.nlm.nih.gov/25704182

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Modulation of ER stress and apoptosis by endoplasmic reticulum calcium leak via translocon during unfolded protein response: involvement of GRP78

Autor: Morad Roudbaraki, Florian Gackière, Sylvie Ducreux, Etienne Dewailly, Philippe Delcourt, Sabine Lotteau, Natalia Prevarskaya, Mehdi Hammadi, Maria Katsogiannou, Christian Slomianny, Agathe Oulidi, Fabien Van Coppenolle, Gilbert Lepage

Publikováno v: FASEB Journal
FASEB Journal, 2012, 27 (4), pp.1600-1609. ⟨10.1096/fj.12-218875⟩

International audience; The endoplasmic reticulum (ER) is involved in many cellular functions, including protein folding and Ca2+ homeostasis. The ability of cells to respond to the ER stress is critical for cell survival, and disruption in such regu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e1012c49c451548480519a679b3b6e4
https://hal.science/hal-03884827

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Human ether à-gogo K(+) channel 1 (hEag1) regulates MDA-MB-231 breast cancer cell migration through Orai1-dependent calcium entry

Autor: Fabrice Matifat, Maud Chasseraud, Valérie Chopin, Halima Ouadid-Ahidouch, Henri Sevestre, Isabelle Dhennin-Duthille, Mehdi Hammadi

Publikováno v: Journal of cellular physiology. 227(12)

Breast cancer (BC) has a poor prognosis due to its strong metastatic ability. Accumulating data present ether a go-go (hEag1) K+ channels as relevant player in controlling cell cycle and proliferation of non-invasive BC cells. However, the role of hE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3099208d2e956912b3f9a61df20917
https://pubmed.ncbi.nlm.nih.gov/22495877

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