Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Mehdi Gharghabi"'
Autor:
Dongju Park, Mehdi Gharghabi, Colleen R. Reczek, Rebecca Plow, Charles Yungvirt, C. Marcelo Aldaz, Kay Huebner
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3729 (2022)
Wwox-deficient human cells show elevated homologous recombination, leading to resistance to killing by double-strand break-inducing agents. Human Wwox binds to the Brca1 981-PPLF-984 Wwox-binding motif, likely blocking the pChk2 phosphorylation site
Externí odkaz:
https://doaj.org/article/cb7f36b8adc34394bccd8ce9ac2ad57e
Publikováno v:
Biomolecules, Vol 11, Iss 2, p 218 (2021)
Arrestins are a small family of four proteins in most vertebrates that bind hundreds of different G protein-coupled receptors (GPCRs). Arrestin binding to a GPCR has at least three functions: precluding further receptor coupling to G proteins, facili
Externí odkaz:
https://doaj.org/article/d0bce2dadd474cc686686acf1355f95e
Autor:
Pu, Zhang, Lindsey T, Brinton, Mehdi, Gharghabi, Steven, Sher, Katie, Williams, Matthew, Cannon, Janek S, Walker, Daniel, Canfield, Larry, Beaver, Casey B, Cempre, Hannah, Phillips, Xuyong, Chen, Pearlly, Yan, Amy, Lehman, Peggy, Scherle, Min, Wang, Kris, Vaddi, Robert, Baiocchi, Ruoning, Wang, Deepa, Sampath, Lapo, Alinari, James S, Blachly, Rosa, Lapalombella
Publikováno v:
Science advances. 8(37)
Using a genome-wide CRISPR screen, we identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::927a146276cb83381867913e3224e499
https://pubmed.ncbi.nlm.nih.gov/36112677
https://pubmed.ncbi.nlm.nih.gov/36112677
Autor:
Mehdi Ghasemi, Zohreh Abdolmaleki, Ramtin Gholizadeh, Mehdi Gharghabi, Ahmad Reza Dehpour, Taraneh Bahremand
Publikováno v:
Journal of Epilepsy Research
Background and Purpose: Licofelone is a dual 5-lipoxygenase/cyclooxygenase inhibitor, with well-documented anti-inflammatory and analgesic effects, which is used for treatment of osteoarthritis. Recent preclinical studies have also suggested neuropro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60880483fb32f66aafe1294c370e1a90
https://doi.org/10.14581/jer.21003
https://doi.org/10.14581/jer.21003
Autor:
Steven Sher, Pu Zhang, Lindsey Brinton, Mehdi Gharghabi, Katie Williams, Matthew Cannon, Janek S. Walker, Daniel Canfield, Larry Beaver, Casey B. Cempre, Hannah Phillips, Xuyong Chen, Pearlly S. Yan, Amy M. Lehman, Peggy Scherle, Min Wang, Kris Vaddi, Robert A. Baiocchi, Ruoning Wang, Deepa Sampath, Lapo Alinari, James S. Blachly, Rosa Lapalombella
Publikováno v:
Blood. 140:681-682
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03f23d71c51a15d3e653befe6c6c75e9
https://doi.org/10.1182/blood-2022-165573
https://doi.org/10.1182/blood-2022-165573
Publikováno v:
Trends Biochem Sci
Three classes of G-protein-coupled receptor (GPCR) partners - G proteins, GPCR kinases, and arrestins - preferentially bind active GPCRs. Our analysis suggests that the structures of GPCRs bound to these interaction partners available today do not re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198f3e9abca8083845695aff859da1f9
https://pubmed.ncbi.nlm.nih.gov/35396120
https://pubmed.ncbi.nlm.nih.gov/35396120
Autor:
Ghorban Taghizadeh, Gelareh Vakilzadeh, Tina Khorshidahmad, Mehdi Gharghabi, Mehdi Sanati, Mehdi Aghsami, Mohammad Sharifzadeh, Shervin Gholizadeh, Hajar Mehdizadeh, Rojin Sharif
Publikováno v:
Behavioural Brain Research. 316:115-124
Oxidative stress and mitochondrial dysfunction play indispensable role in memory and learning impairment. Growing evidences have shed light on anti-oxidative role for melatonin in memory deficit. We have previously reported that inhibition of protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad221488e85205b4c1d010fafa5430d2
https://doi.org/10.1016/j.bbr.2016.08.040
https://doi.org/10.1016/j.bbr.2016.08.040
Autor:
Ameneh, Eslamparast, Reza, Abbasgholizadeh, Seyed Nasser, Ostad, Mehdi, Gharghabi, Mohammad Hossein, Ghahremani
Publikováno v:
Iranian Journal of Pharmaceutical Research : IJPR
Fragile histidine triad (FHIT) serves a critical function as a tumor suppressor that inhibits p53 degradation by mouse double minute 2 (MDM2). The functional domains of FHIT involved in tumor inhibition was interpreted. In-silico screening data were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::40272202fa6146931ba00e00d7499f1a
https://pubmed.ncbi.nlm.nih.gov/31089360
https://pubmed.ncbi.nlm.nih.gov/31089360
Publikováno v:
Biomolecules
Biomolecules, Vol 11, Iss 218, p 218 (2021)
Biomolecules, Vol 11, Iss 218, p 218 (2021)
Arrestins are a small family of four proteins in most vertebrates that bind hundreds of different G protein-coupled receptors (GPCRs). Arrestin binding to a GPCR has at least three functions: precluding further receptor coupling to G proteins, facili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb37c19cff76b3c202205fffa7327f59
https://doi.org/10.3390/biom11020218
https://doi.org/10.3390/biom11020218
Autor:
Mohammad Hossein Ghahremani, Seyed Nasser Ostad, Hamed Montazeri, Homa Mohseni kouchesfehani, Mehdi Gharghabi, Fereshteh Mir Mohammadrezaei
Publikováno v:
Cellular Signalling. 25:126-132
FHIT (Fragile Histidin Triad) is a tumor suppressor gene involved in regulating cell death during DNA damage conditions. The exact mechanism of DNA damage-induced FHIT signaling is not well understood. It is known that p38 kinase and CHK2 kinase are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca341ab5dcc5eb715c8db2ab6672a7d8
https://doi.org/10.1016/j.cellsig.2012.09.019
https://doi.org/10.1016/j.cellsig.2012.09.019