Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Mehdi, Touat"'
Autor:
Vincent Jonchère, Hugo Montémont, Enora Le Scanf, Aurélie Siret, Quentin Letourneur, Emmanuel Tubacher, Christophe Battail, Assane Fall, Karim Labreche, Victor Renault, Toky Ratovomanana, Olivier Buhard, Ariane Jolly, Philippe Le Rouzic, Cody Feys, Emmanuelle Despras, Habib Zouali, Rémy Nicolle, Pascale Cervera, Magali Svrcek, Pierre Bourgoin, Hélène Blanché, Anne Boland, Jérémie Lefèvre, Yann Parc, Mehdi Touat, Franck Bielle, Danielle Arzur, Gwennina Cueff, Catherine Le Jossic-Corcos, Gaël Quéré, Gwendal Dujardin, Marc Blondel, Cédric Le Maréchal, Romain Cohen, Thierry André, Florence Coulet, Pierre de la Grange, Aurélien de Reyniès, Jean-François Fléjou, Florence Renaud, Agusti Alentorn, Laurent Corcos, Jean-François Deleuze, Ada Collura, Alex Duval
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-26 (2024)
Abstract Background Microsatellite instability (MSI) due to mismatch repair deficiency (dMMR) is common in colorectal cancer (CRC). These cancers are associated with somatic coding events, but the noncoding pathophysiological impact of this genomic i
Externí odkaz:
https://doaj.org/article/87efc7be65b6480c8bf4509103a6aab4
Autor:
Marine Baron, Karim Labreche, Marianne Veyri, Nathalie Désiré, Amira Bouzidi, Fatou Seck-Thiam, Frédéric Charlotte, Alice Rousseau, Véronique Morin, Cécilia Nakid-Cordero, Baptiste Abbar, Alberto Picca, Marie Le Cann, Noureddine Balegroune, Nicolas Gauthier, Ioannis Theodorou, Mehdi Touat, Véronique Morel, Franck Bielle, Assia Samri, Agusti Alentorn, Marc Sanson, Damien Roos-Weil, Corinne Haioun, Elsa Poullot, Anne Langlois de Septenville, Frédéric Davi, Amélie Guihot, Pierre-Yves Boelle, Véronique Leblond, Florence Coulet, Jean-Philippe Spano, Sylvain Choquet, Brigitte Autran, IDeATIon study group
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Non-Hodgkin lymphomas (NHL) commonly occur in immune-deficient (ID) patients, both HIV-infected and transplanted, and are often EBV-driven with cerebral localization, raising the question of tumor immunogenicity, a critical issue for treatment respon
Externí odkaz:
https://doaj.org/article/4ed12c460a174df8aed7d61d4a12e426
Autor:
Agostina Stradella, Francois Ghiringhelli, Ana Maia, Macarena Gonzalez, Cécile Gouttefangeas, Ulrich Herrlinger, David Reardon, Ahmed Idbaih, Patrick Wen, Ghazaleh Tabatabai, Wolfgang Wick, Mirjam Renovanz, Maria Vieito Villar, Christophe Bonny, Joao Gamelas Magalhaes, Hélène Toussaint, Jean-Michel Paillarse, Marta GilMartin, Iris Mildenberger, Michael C Burger, Alice Hervieu, Mehdi Touat, Antje Wick
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/b66bf531835946ef99e16b169d7cc47a
Autor:
Isaias Hernández-Verdin, Kadir C. Akdemir, Daniele Ramazzotti, Giulio Caravagna, Karim Labreche, Karima Mokhtari, Khê Hoang-Xuan, Matthieu Peyre, Franck Bielle, Mehdi Touat, Ahmed Idbaih, Alex Duval, Marc Sanson, Agustí Alentorn
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-14 (2022)
Abstract Activation-induced cytidine deaminase, AICDA or AID, is a driver of somatic hypermutation and class-switch recombination in immunoglobulins. In addition, this deaminase belonging to the APOBEC family may have off-target effects genome-wide,
Externí odkaz:
https://doaj.org/article/10e4ff93711e45efae0a1c2b4a7ff33b
Autor:
Shannon Coy, Shu Wang, Sylwia A. Stopka, Jia-Ren Lin, Clarence Yapp, Cecily C. Ritch, Lisa Salhi, Gregory J. Baker, Rumana Rashid, Gerard Baquer, Michael Regan, Prasidda Khadka, Kristina A. Cole, Jaeho Hwang, Patrick Y. Wen, Pratiti Bandopadhayay, Mariarita Santi, Thomas De Raedt, Keith L. Ligon, Nathalie Y. R. Agar, Peter K. Sorger, Mehdi Touat, Sandro Santagata
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-24 (2022)
The components of the glioma immune microenvironment and their roles in promoting tumourigenesis remain poorly understood. Here, the use of single-cell RNA sequencing and multiplexed tissue-imaging in adult and pediatric high-grade gliomas reveals th
Externí odkaz:
https://doaj.org/article/253b0fa0fb184487ac96b60cc93df6f3
Autor:
Marianne Gazzano, Christophe Parizot, Dimitri Psimaras, Aurore Vozy, Marine Baron, Baptiste Abbar, Vincent Fallet, Elena Litvinova, Anthony Canellas, Cristina Birzu, Valérie Pourcher, Mehdi Touat, Nicolas Weiss, Sophie Demeret, Damien Roos-Weil, Jean-Philippe Spano, Celeste Lebbe, Joe-Elie Salem, Jacques Cadranel, Baptiste Hervier, Guy Gorochov, Amélie Guihot
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immune checkpoint inhibitors (ICI) widely improved the treatment of solid and hematologic malignancies. Yet, a remarkable proportion of patients receiving ICI develop immune related adverse events (irAEs) which are difficult to define as treatment-re
Externí odkaz:
https://doaj.org/article/1eac44753a3647478311d1fe3020e8f6
Autor:
Marion Opatowski, Christian Brun-Buisson, Mehdi Touat, Jérôme Salomon, Didier Guillemot, Philippe Tuppin, Laurence Watier
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Antibiotic resistance is increasing among urinary pathogens, resulting in worse clinical and economic outcomes. We analysed factors associated with antibiotic-resistant bacteria (ARB) in patients hospitalized for urinary tract inf
Externí odkaz:
https://doaj.org/article/addc63f98cca4f1e84a14d0900f7b482
Autor:
Max A. Stockslager, Seth Malinowski, Mehdi Touat, Jennifer C. Yoon, Jack Geduldig, Mahnoor Mirza, Annette S. Kim, Patrick Y. Wen, Kin-Hoe Chow, Keith L. Ligon, Scott R. Manalis
Publikováno v:
Cell Reports, Vol 37, Iss 1, Pp 109788- (2021)
Summary: Functional precision medicine aims to match individual cancer patients to optimal treatment through ex vivo drug susceptibility testing on patient-derived cells. However, few functional diagnostic assays have been validated against patient o
Externí odkaz:
https://doaj.org/article/e91ca42247b7413da4ad84cd61fab80b
Autor:
Amira Bouzidi, Karim Labreche, Marine Baron, Marianne Veyri, Jérôme Alexandre Denis, Mehdi Touat, Marc Sanson, Frédéric Davi, Erell Guillerm, Stéphanie Jouannet, Frédéric Charlotte, Franck Bielle, Sylvain Choquet, Pierre-Yves Boëlle, Jacques Cadranel, Véronique Leblond, Brigitte Autran, Jean-Marc Lacorte, Jean-Philippe Spano, Florence Coulet, the IDEATION study group, Ahmed Idbaih, Noureddine Balegroune, Amélie Guihot, Ioannis Theodorou, Agusti Alentorn, Isabelle Brocheriou, Anne-Geneviève, Damien Roos Weil, Alberto Picca
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Cell-free DNA (cfDNA) analysis is a minimally invasive method that can be used to detect genomic abnormalities by directly testing a blood sample. This method is particularly useful for immunosuppressed patients, who are at high risk of complications
Externí odkaz:
https://doaj.org/article/d60de3ac6cae402cb2bbc555becfa333
Autor:
David Capper, Guido Reifenberger, Pim J French, Leonille Schweizer, Michael Weller, Mehdi Touat, Simone P Niclou, Philipp Euskirchen, Christine Haberler, Monika E Hegi, Sebastian Brandner, Emilie Le Rhun, Roberta Rudà, Marc Sanson, Ghazaleh Tabatabai, Felix Sahm, Patrick Y Wen, Pieter Wesseling, Matthias Preusser, Martin J van den Bent
Publikováno v:
Neuro-Oncology, 25(5), 813-826. Oxford University Press
Capper, D, Reifenberger, G, French, P J, Schweizer, L, Weller, M, Touat, M, Niclou, S P, Euskirchen, P, Haberler, C, Hegi, M E, Brandner, S, le Rhun, E, Rudà, R, Sanson, M, Tabatabai, G, Sahm, F, Wen, P Y, Wesseling, P, Preusser, M & van den Bent, M J 2023, ' EANO guideline on rational molecular testing of gliomas, glioneuronal, and neuronal tumors in adults for targeted therapy selection ', Neuro-Oncology, vol. 25, no. 5, pp. 813-826 . https://doi.org/10.1093/neuonc/noad008
Capper, D, Reifenberger, G, French, P J, Schweizer, L, Weller, M, Touat, M, Niclou, S P, Euskirchen, P, Haberler, C, Hegi, M E, Brandner, S, le Rhun, E, Rudà, R, Sanson, M, Tabatabai, G, Sahm, F, Wen, P Y, Wesseling, P, Preusser, M & van den Bent, M J 2023, ' EANO guideline on rational molecular testing of gliomas, glioneuronal, and neuronal tumors in adults for targeted therapy selection ', Neuro-Oncology, vol. 25, no. 5, pp. 813-826 . https://doi.org/10.1093/neuonc/noad008
The mainstay of treatment for adult patients with gliomas, glioneuronal and neuronal tumors consists of combinations of surgery, radiotherapy, and chemotherapy. For many systemic cancers, targeted treatments are a part of the standard of care, howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2437b564180c61f575afa7e4b837d6e
https://doi.org/10.1093/neuonc/noad008
https://doi.org/10.1093/neuonc/noad008