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Akademický článek

Palladium supported magnetic Fucus Vesiculosus extract as a natural and novel catalyst for the synthesis of N-alkyl-2-(4-methyl-1-oxoisoquinolin-2(1H)-yl)-2-phenylacetamide derivatives

Autor: Faeze Yousefnejad, Saeed Bahadorikhalili, Maryam Esmkhani, Mehdi Adib, Shahrzad Javanshir, Samanehsadat Hosseini, Bagher Larijani, Mohammad Mahdavi

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)

Abstract In this paper, a novel catalyst is introduced based on the immobilization of palladium onto magnetic Fucus Vesiculosus extract (Pd@mFuVe catalyst). For the synthesis of Pd@mFuVe catalyst, Fucus Vesiculosus extract is obtained from the plant

Externí odkaz: https://doaj.org/article/f73a21f423f34b2689ca469909d43449

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Akademický článek

Design, synthesis, in vitro α-glucosidase inhibition, docking, and molecular dynamics of new phthalimide-benzenesulfonamide hybrids for targeting type 2 diabetes

Autor: Mohammad Askarzadeh, Homa Azizian, Mehdi Adib, Maryam Mohammadi-Khanaposhtani, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Sayed Mahmoud Sajjadi-Jazi, Bagher Larijani, Haleh Hamedifar, Mohammad Mahdavi

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)

Abstract In the present work, a new series of 14 novel phthalimide-benzenesulfonamide derivatives 4a–n were synthesized, and their inhibitory activity against yeast α-glucosidase was screened. The obtained results indicated that most of the newly

Externí odkaz: https://doaj.org/article/a1591543e29a4767b4e1c86e24a91d29

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Structure-based drug discovery and antimicrobial activity of ciprofloxacin‐grafted Ugi adducts

Autor: Behnam, Tahmasebi, Aida, Iraji, Maedeh, Sherafati, Ali, Moazzam, Seyed Alireza, Akhlagh, Mehdi, Adib, Mohammad, Mahdavi

Publikováno v: Journal of Biomolecular Structure and Dynamics. :1-10

A new series of ciprofloxacin-derived Ugi adducts were rationally designed and synthesized. The synthesized molecules were explored for their potential antimicrobial activities against four pathogenic microorganisms. Among these derivatives, compound

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea6ed4db45ed008284e5a593cbd9cb58
https://doi.org/10.1080/07391102.2022.2130985

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A Facile and Efficient One-Pot Procedure for the Synthesis of Novel 2-Substituted 3-Thioxoisoindolin-1-one Derivatives

Autor: Mohammad Mahdavi, Mehdi Adib, Fatemeh Gholami, Ali Moazzam, Saeed Bahadorikhalili, Samanesadat Hosseini, Bagher Larijani

Publikováno v: Synlett. 33:1729-1732

In this paper, a novel and efficient method is reported for the synthesis of novel 2-substituted 3-thioxoisoindolin-1-one derivatives. The method is based on the solvent-free reaction of 2-carboxybenzaldehyde with aliphatic amines and sulfur at 100 �

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::89d207fbc1b402a95a641c83b65dd39f
https://doi.org/10.1055/a-1912-2293

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Sulfonamide-phosphonate hybrids as new carbonic anhydrase inhibitors: In vitro enzymatic inhibition, molecular modeling, and ADMET prediction

Autor: Samira Zareei, Maryam Mohammadi-Khanaposhtani, Mehdi Adib, Mohammad Mahdavi, Parham Taslimi

Publikováno v: Journal of Molecular Structure

In the presented work, we report the synthesis of a new series of sulfonamide-phosphonate hybrids 4a-m. These newly synthesized compounds were assessed for their inhibitory effects toward two human carbonic anhydrase isoforms I and II (hCA I and II).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca373ab908cf47bfd77749fc5f94e063
http://hdl.handle.net/11772/11097

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Copper Supported Imidazolylpyridine Modified SPION as an Efficient Catalyst for Eco-friendly, One-Pot and Green Synthesis of Novel (3-Cyanothiophen-2-yl)-N-(arylsulfonyl)acetimidamide Derivatives

Autor: Mohammad Mahdavi, Mehdi Adib, Mohammad Askarzadeh

Publikováno v: Current organic synthesis.

Background: In this paper, a novel catalyst is synthesized and characterized by immobilizing copper onto imidazopyridine-modified superparamagnetic iron oxide nanoparticles (SPION). Methods: The catalyst is characterized by several methods, including

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::757fcfc64edf45b7055fc190133b3ee7
https://pubmed.ncbi.nlm.nih.gov/35748544

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