Anti-integrin αvβ6 Autoantibodies are Increased in Primary Sclerosing Cholangitis Patients With Concomitant Inflammatory Bowel Disease and Correlate With Liver Disease Severity.

Autor: Bloemen H; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York., Livanos AE; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address: alexandra.livanos@mountsinai.org., Martins A; Schiff Center for Liver Diseases, University of Miami Leonard M. Miller School of Medicine, Miami, Florida., Dean R; Division of Gastroenterology and Hepatology, University of California Davis School of Medicine, Sacramento, California., Bravo AC; Division of Gastroenterology, Hospital Beatriz Ângelo, Loures, Portugal., Bourgonje AR; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York., Tankelevich M; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York., Herb J; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York., Cho J; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York., Santos AA; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Lisbon, Portugal., Rodrigues CMP; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Lisbon, Portugal., Petralia F; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York., Colombel JF; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York., Bowlus CL; Division of Gastroenterology and Hepatology, University of California Davis School of Medicine, Sacramento, California., Schiano T; Recanati/Miller Transplantation Institute, Division of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York., Torres J; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York; Division of Gastroenterology, Hospital Beatriz Ângelo, Loures, Portugal; Faculty of Medicine, Universidade de Lisboa, Lisbon, Portugal; Division of Gastroenterology, Hospital da Luz, Lisbon, Portugal., Levy C; Schiff Center for Liver Diseases, University of Miami Leonard M. Miller School of Medicine, Miami, Florida; Division of Digestive Health and Liver Diseases, University of Miami Miller School of Medicine, Miami, Florida. Electronic address: clevy@med.miami.edu., Mehandru S; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address: saurabh.mehandru@mssm.edu.

Publikováno v: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association [Clin Gastroenterol Hepatol] 2024 Oct 25. Date of Electronic Publication: 2024 Oct 25.

Unravelling the Oral-Gut Axis: Interconnection Between Periodontitis and Inflammatory Bowel Disease, Current Challenges, and Future Perspective.

Autor: Tanwar H; Division of Periodontology, University of Maryland School of Dentistry, Baltimore, MD, USA., Gnanasekaran JM; Division of Periodontology, University of Maryland School of Dentistry, Baltimore, MD, USA., Allison D; Division of Periodontology, University of Maryland School of Dentistry, Baltimore, MD, USA., Chuang LS; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., He X; Department of Microbiology, The Forsyth Institute, Cambridge, MA, USA., Aimetti M; Department of Surgical Sciences, C.I.R. Dental School, University of Turin, Turin, Italy., Baima G; Department of Surgical Sciences, C.I.R. Dental School, University of Turin, Turin, Italy., Costalonga M; Department of Diagnostic and Biological Sciences, School of Dentistry, University of Minnesota, Minneapolis, MN, USA., Cross RK; Division of Gastroenterology & Hepatology, University of Maryland School of Medicine, Baltimore, MD, USA., Sears C; Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Mehandru S; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Cho J; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Colombel JF; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Raufman JP; Division of Gastroenterology & Hepatology, University of Maryland School of Medicine, Baltimore, MD, USA., Thumbigere-Math V; Division of Periodontology, University of Maryland School of Dentistry, Baltimore, MD, USA.; National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD, USA.

Publikováno v: Journal of Crohn's & colitis [J Crohns Colitis] 2024 Aug 14; Vol. 18 (8), pp. 1319-1341.

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Gut-associated lymphoid tissue attrition associates with response to anti-α4β7 therapy in ulcerative colitis.

Autor: Canales-Herrerias P; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Uzzan M; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Paris Est Créteil University UPEC, Assistance Publique-Hôpitaux de Paris (AP-HP), Henri Mondor Hospital, Gastroenterology Department, Fédération Hospitalo-Universitaire TRUE (InnovaTive theRapy for immUne disordErs), Créteil F-94010, France., Seki A; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Czepielewski RS; Department of Pathology, Washington University School of Medicine, St. Louis, MO, USA., Verstockt B; Department of Gastroenterology and Hepatology, University Hospitals Leuven, Leuven, Belgium.; Translational Research in Gastrointestinal Disorders, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium., Livanos AE; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Raso F; Department of Pathology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Dunn A; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Dai D; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Wang A; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Al-Taie Z; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Martin J; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Nantes Université, CHU Nantes, Inserm, Centre de Recherche Translationelle en Transplantation et Immunologie, UMR 1064, Nantes, France.; CHU Nantes, Nantes Université, Laboratoire d'Immunologie, CIMNA, Nantes, France., Laurent T; Nantes Université, CHU Nantes, Inserm, Centre de Recherche Translationelle en Transplantation et Immunologie, UMR 1064, Nantes, France.; CHU Nantes, Nantes Université, Laboratoire d'Immunologie, CIMNA, Nantes, France., Ko HM; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Tokuyama M; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Tankelevich M; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Meringer H; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Cossarini F; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Jha D; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Krek A; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Paulsen JD; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Taylor MD; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Nakadar MZ; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Wong J; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Erlich EC; Department of Pathology, Washington University School of Medicine, St. Louis, MO, USA., Mintz RL; Department of Pathology, Washington University School of Medicine, St. Louis, MO, USA., Onufer EJ; Division of Pediatric Surgery, Department of Surgery, St. Louis Children's Hospital, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Helmink BA; Department of Surgery, Section of Surgical Oncology, Washington University School of Medicine, St. Louis, MO, USA., Sharma K; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Rosenstein A; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Ganjian D; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Chung G; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Dawson T; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Juarez J; Takeda Pharmaceuticals, Cambridge, MA, USA., Yajnik V; Takeda Pharmaceuticals, Cambridge, MA, USA., Cerutti A; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Translational Clinical Research Program, Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain.; Catalan Institute for Research and Advanced Studies (ICREA), Barcelona, Spain., Faith JJ; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Suarez-Farinas M; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Argmann C; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Petralia F; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Randolph GJ; Department of Pathology, Washington University School of Medicine, St. Louis, MO, USA., Polydorides AD; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Reboldi A; Department of Pathology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Colombel JF; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Mehandru S; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Publikováno v: Science immunology [Sci Immunol] 2024 Apr 19; Vol. 9 (94), pp. eadg7549. Date of Electronic Publication: 2024 Apr 19.

Phenotype and function of nasal dendritic cells

Autor: Lee, H, Ruane, D, Law, K, Ho, Y, Garg, A, Rahman, A, Esterházy, D, Cheong, C, Goljo, E, Sikora, A G, Mucida, D, Chen, B K, Govindraj, S, Breton, G, Mehandru, S

Publikováno v: In Mucosal Immunology September 2015 8(5):1083-1098