Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mehal Churiwal"'
Autor:
Abigail H. Cleveland, Daniel Malawsky, Mehal Churiwal, Claudia Rodriguez, Frances Reed, Matthew Schniederjan, Jose E. Velazquez Vega, Ian Davis, Timothy R. Gershon
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-19 (2023)
Abstract We show that Polycomb Repressive Complex-2 (PRC2) components EED and EZH2 maintain neural identity in cerebellar granule neuron progenitors (CGNPs) and SHH-driven medulloblastoma, a cancer of CGNPs. Proliferating CGNPs and medulloblastoma ce
Externí odkaz:
https://doaj.org/article/da95e9bb36f24f898a4974b26fb6a823
Autor:
Judy Smith, Christopher Basham, Maureen Whittelsey, Jessica T. Lin, Tyler Rapp, Meredith S. Muller, Srijana Bhattarai Chhetri, Christy Litel, Kathleen Tompkins, Mehal Churiwal, Carla Cerami, Salman Khan, Lakshmanane Premkumar, Kelly Lin
Publikováno v:
The American Journal of Tropical Medicine and Hygiene
Point-of-care (POC) tests to detect SARS-CoV-2 antibodies offer quick assessment of serostatus after natural infection or vaccination. We compared the field performance of the BioMedomics COVID-19 IgM/IgG Rapid Antibody Test against an ELISA in 303 p
Autor:
Yong Yean Kim, Robert G. Hawley, Mehal Churiwal, Teresa S. Hawley, Christine N. Evans, Raj Chari, David Milewski, Ranuka Sinniah, Young K. Song, Hsien-Chao Chou, Xinyu Wen, Ying Pang, Jing Wu, Craig J. Thomas, Jun S. Wei, Michele Ceribelli, Javed Khan
Publikováno v:
Cancer Research. 83:3538-3538
Background: Oncogenic fusion genes are attractive therapeutic targets due to their tumor-specific expression and driver roles in cancers. PAX3-FOXO1 (P3F) is the dominant oncogenic driver of fusion-positive rhabdomyosarcoma (FP-RMS) with no targeted
Autor:
Kimberly A. Powers, Katie R. Mollan, Jonathan J. Juliano, Srijana Bhattarai Chhetri, Christopher Basham, Maureen Whittelsey, Kathleen Tompkins, Rebecca Rubinstein, Carla Cerami, Lakshmanane Premkumar, Judy Smith, Haoming Zhang, Tyler Rapp, Kelly Lin, Meredith S. Muller, Zachary R Popkin-Hall, Christy Litel, Feng-Chang Lin, David A. Wohl, Jessica T. Lin, Mehal Churiwal, Salman Khan, Faith Claman
Background Households are hot spots for severe acute respiratory syndrome coronavirus 2 transmission. Methods This prospective study enrolled 100 coronavirus disease 2019 (COVID-19) cases and 208 of their household members in North Carolina though Oc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c564c5d6c319aa6896a73811916b25
https://researchonline.lshtm.ac.uk/id/eprint/4662404/7/Cerami_etal_2021_Household-transmission-of-SARS-CoV-2.pdf
https://researchonline.lshtm.ac.uk/id/eprint/4662404/7/Cerami_etal_2021_Household-transmission-of-SARS-CoV-2.pdf
Autor:
Yong Yean Kim, Girma Woldemichael, Berkley Gryder, Silvia Pomella, Ranuka Sinniah, Josh Kowalczyk, Young Song, Mehal Churiwal, Joseph Barchi, John Schneekloth, Xinyu Wen, Hsein-Chao Chou, Barry Okeefe, John Shern, Robert Hawley, Javed Khan
Publikováno v:
Cancer Research. 82:703-703
BACKGROUND: The PAX3/7-FOXO1 (P3F) fusion transcription factor is the oncogenic driver in fusion-positive rhabdomyosarcoma (FP-RMS). P3F drives oncogenesis in FP-RMS through transcriptional modulation of downstream target genes. Thus, P3F represents
Autor:
Judy Smith, Jonathan J. Juliano, Jessica T. Lin, Tyler Rapp, Srijana Bhattarai Chhetri, David A. Wohl, Christy Litel, Meredith S. Muller, Christopher Basham, Maureen Whittelsey, Feng-Chang Lin, Mehal Churiwal, Carla Cerami, Kathleen Tompkins, Salman Khan, Faith Claman, Haoming Zhang, Rebecca Rubinstein, Lakshmanane Premkumar, Katie R. Mollan, Kelly Lin
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
BackgroundFew prospective studies of SARS-CoV-2 transmission within households have been reported from the United States, where COVID-19 cases are the highest in the world and the pandemic has had disproportionate impact on communities of color.Metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc5cc3f9a735553b529ee2c8a7d05f1
https://doi.org/10.1101/2021.03.10.21253173
https://doi.org/10.1101/2021.03.10.21253173
Publikováno v:
Neuro-Oncology
Hyperactivation of Sonic Hedgehog (SHH) signaling pathway drives tumor progression in the largest medulloblastoma subgroup. During cerebellar development, promoters of SHH target genes show inhibitory trimethylation of histone H3 at lysine 27 (H3K27m